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SLC26A3 Antibody

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Western Blot: SLC26A3 Antibody [NBP1-84450] - Analysis in control (vector only transfected HEK293T lysate) and SLC26A3 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T ...read more
Immunohistochemistry-Paraffin: SLC26A3 Antibody [NBP1-84450] - Analysis in human colon and skeletal muscle tissues using NBP1-84450 antibody. Corresponding SLC26A3 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: SLC26A3 Antibody [NBP1-84450] - Staining of human colon shows moderate positivity in glandular cells of apical membrane.
Immunohistochemistry-Paraffin: SLC26A3 Antibody [NBP1-84450] - Staining of human skeletal muscle shows no positivity in myocytes as expected.
Immunohistochemistry-Paraffin: SLC26A3 Antibody [NBP1-84450] - Staining of human small intestine shows moderate to strong positivity in apical membrane in glandular cells.

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, IHC, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

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SLC26A3 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: DQPINTTDLPFHIDWNDDLPLNIEVPKISLHSLILDFSAVSFLDVSSVRGLKSILQEFIRIKVDVYIVGTDDDFIEKLNRYEFFDGEVKSSIFFLTIHDAVLHILMKKDYSTSKFNP
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SLC26A3
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry Whole-Mount Reported in scientific literature (PMID:31708126)
  • Immunohistochemistry 1:200 - 1:500
  • Immunohistochemistry-Paraffin 1:200 - 1:500
  • Western Blot 0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
SLC26A3 Protein (NBP1-84450PEP)
Publications
Read Publication using
NBP1-84450 in the following applications:

Reactivity Notes

Mouse reactivity reported in scientific literature (PMID: 31708126). Rat (85%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for SLC26A3 Antibody

  • chloride anion exchanger
  • CLD
  • congenital chloride diarrhea
  • down-regulated in adenoma protein
  • DRADown-regulated in adenoma
  • Protein DRA
  • Solute carrier family 26 member 3
  • solute carrier family 26, member 3

Background

SLC26A3 is encoded by this gene is a transmembrane glycoprotein that functions as a sulfate transporter. It is localized to the mucosa of the lower intestinal tract, particularly to the apical membrane of columnar epithelium and some goblet cells. Mutations in this gene have been associated with congenital chloride diarrhea.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for SLC26A3 Antibody (NBP1-84450)(1)

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 1 application: IHC-WhMt.


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IHC-WhMt
(1)
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Product General Protocols

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Video Protocols

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Secondary Antibodies

 

Isotype Controls

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Research Areas for SLC26A3 Antibody (NBP1-84450)

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Blogs on SLC26A3.

Next-Gen DNA Sequencing and SLC26A3 Research
The SLC26A3, also known as DRA (downregulated-in-adenoma) gene is a member of the sulphate anion transporter family, serving an important role in the exchange and transport of chloride, bicarbonate and sulphate ions at plasma membrane sites. We at Nov...  Read full blog post.

Antibody Therapies and the New Generation of DNA Sequencing
Our antibody database is primarily focused on protein-coding genes. Although they form only 1% of the total human genome, these important genes account for 85% of the mutations that lead to disease.DNA sequencing (defining the sequence of the 4 base...  Read full blog post.

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Bioinformatics

Gene Symbol SLC26A3