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Sirtuin 1/SIRT1 Antibody (1F3) [Janelia Fluor® 646]

Name: Sirtuin 1/SIRT1 Antibody (1F3) [Janelia Fluor&#174; 646]
Brand: Novus Biologicals
SKU: NBP1-51641JF646
Price: 499 USD

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Product Details

Summary

Reactivity	Hu, Mu, Rt, Pm, RbSpecies Glossary
Applications	WB, ELISA, Flow, ICC/IF, IHC, IHC
Clone	1F3
Clonality	Monoclonal
Host	Mouse
Conjugate	Janelia Fluor 646

Order Details

View Available Conjugates

Catalog# & Conjugate	Size	Price
Alexa Fluor 350 NBP1-51641AF350

Alexa Fluor 405 NBP1-51641AF405

Alexa Fluor 488 NBP1-51641AF488

Alexa Fluor 532 NBP1-51641AF532

Alexa Fluor 594 NBP1-51641AF594

Alexa Fluor 647 NBP1-51641AF647

Alexa Fluor 700 NBP1-51641AF700

Alexa Fluor 750 NBP1-51641AF750

Allophycocyanin NBP1-51641APC

Biotin NBP1-51641B

DyLight 350 NBP1-51641UV

DyLight 405 NBP1-51641V

DyLight 488 NBP1-51641G

DyLight 550 NBP1-51641R

DyLight 594 NBP1-51641DL594

DyLight 650 NBP1-51641C

DyLight 680 NBP1-51641FR

DyLight 755 NBP1-51641IR

FITC NBP1-51641F

HRP NBP1-51641H

Janelia Fluor 549 NBP1-51641JF549

PE NBP1-51641PE

PerCP NBP1-51641PCP

Unconjugated NBP1-51641

mFluor Violet 450 SE NBP1-51641MFV450

mFluor Violet 500 SE NBP1-51641MFV500

mFluor Violet 610 SE NBP1-51641MFV610

View Available Formulations

Catalog# & Formulation	Size	Price
Standard Formulation NBP1-51641

BSA Free NBP1-51641

BSA Free NBP1-51641SS

Azide and BSA Free NBP2-80949

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Conjugate	Catalog #	Availability	Size	Price
Alexa Fluor 350	NBP1-51641AF350
Alexa Fluor 405	NBP1-51641AF405
Alexa Fluor 488	NBP1-51641AF488
Alexa Fluor 532	NBP1-51641AF532
Alexa Fluor 594	NBP1-51641AF594
Alexa Fluor 647	NBP1-51641AF647
Alexa Fluor 700	NBP1-51641AF700
Alexa Fluor 750	NBP1-51641AF750
Allophycocyanin	NBP1-51641APC
Biotin	NBP1-51641B
DyLight 350	NBP1-51641UV
DyLight 405	NBP1-51641V
DyLight 488	NBP1-51641G
DyLight 550	NBP1-51641R
DyLight 594	NBP1-51641DL594
DyLight 650	NBP1-51641C
DyLight 680	NBP1-51641FR
DyLight 755	NBP1-51641IR
FITC	NBP1-51641F
HRP	NBP1-51641H
Janelia Fluor 549	NBP1-51641JF549
PE	NBP1-51641PE
PerCP	NBP1-51641PCP
Unconjugated	NBP1-51641
mFluor Violet 450 SE	NBP1-51641MFV450
mFluor Violet 500 SE	NBP1-51641MFV500
mFluor Violet 610 SE	NBP1-51641MFV610

Sirtuin 1/SIRT1 Antibody (1F3) [Janelia Fluor® 646] Summary

Immunogen	Purified recombinant fragment of human SIRT1 (amino acids: 265-452) expressed in E. coli. [UniProt# Q96EB6]
Isotype	IgG1
Clonality	Monoclonal
Host	Mouse
Gene	SIRT1
Purity	Ammonium sulfate precipitation
Innovator's Reward	Test in a species/application not listed above to receive a full credit towards a future purchase. Learn about the Innovator's Reward

Applications/Dilutions

Dilutions	ELISA Flow (Intracellular) Flow Cytometry Immunocytochemistry/ Immunofluorescence Immunohistochemistry Free-Floating Immunohistochemistry Immunohistochemistry-Paraffin Western Blot
Application Notes	Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Use in Rabbit reported in scientific literature (PMID:32179074).

Packaging, Storage & Formulations

Storage	Store at 4C in the dark.
Buffer	50mM Sodium Borate
Preservative	0.05% Sodium Azide
Purity	Ammonium sulfate precipitation

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Sirtuin 1/SIRT1 Antibody (1F3) [Janelia Fluor® 646]

EC 3.5.1
S. cerevisiae, homolog) 1
SIR2alpha
SIR2L1
SIR2-like protein 1
SIRT1
Sirtuin 1

Background

The S. cerevisiae silent information regulator 2 (Sir2) protein is an NAD+-dependent histone deacetylase (HDACs) that plays a critical role in transcriptional silencing, genome stability, and longevity (1-2). Part of the Sirtuin family (Sir2, Sir3, Sir3), yeast Sir2 is the founding member of Class III HDACs. A human homologue of Sir2 , SIRT1, regulates the activity of the p53 tumor suppressor and inhibits apoptosis (3-4).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

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Bioinformatics

Gene Symbol

SIRT1

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At	=	A. thaliana	SyHa	=	Golden Syrian Hamster
All	=	All Species	Ha	=	Hamster
An	=	Animal	Hu	=	Human
ArHa	=	Armenian Hamster	I	=	Insect
Av	=	Avian	Ll	=	Llama
Bb	=	Baboon	Ma	=	Mammal
Ba	=	Bacteria	Mk	=	Monkey
Bv	=	Bovine	Mu	=	Mouse
Ca	=	Canine	Multi	=	Multi-species
Ce	=	C. Elegans	NA	=	Non-species specific
Ch	=	Chicken	Or	=	Orangutan
ChHa	=	Chinese Hamster	Pl	=	Plant
Cm	=	Cynomolgus Monkey	Pm	=	Primate
Do	=	Donkey	Po	=	Porcine
Dr	=	Drosophilia	Rb	=	Rabbit
Ec	=	E. Coli	Rt	=	Rat
Eq	=	Equine	RM	=	Rhesus Macaque
Fe	=	Feline	Sh	=	Sheep
Ft	=	Ferret	Vb	=	Vertebrate
Fi	=	Fish	Vi	=	Virus
Fu	=	Fungi	Xp	=	Xenopus
Ge	=	Gerbil	Ye	=	Yeast
GP	=	Guinea Pig	Ze	=	Zebrafish
Gt	=	Goat

Sirtuin 1/SIRT1 Antibody (1F3) [Janelia Fluor® 646]

Species Glossary

Images

Product Details

Order Details

Sirtuin 1/SIRT1 Antibody (1F3) [Janelia Fluor® 646] Summary

Applications/Dilutions

Reactivity Notes

Packaging, Storage & Formulations

Notes

Alternate Names for Sirtuin 1/SIRT1 Antibody (1F3) [Janelia Fluor® 646]

Background

Limitations

Customers Who Viewed This Item Also Viewed...

Publications for Sirtuin 1/SIRT1 Antibody (NBP1-51641JF646) (0)

Reviews for Sirtuin 1/SIRT1 Antibody (NBP1-51641JF646) (0)

Product General Protocols

Video Protocols

FAQs for Sirtuin 1/SIRT1 Antibody (NBP1-51641JF646) (0)

Secondary Antibodies

Isotype Controls

Additional Sirtuin 1/SIRT1 Products

Research Areas for Sirtuin 1/SIRT1 Antibody (NBP1-51641JF646)

Blogs on Sirtuin 1/SIRT1

Customers Who Bought This Also Bought

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