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SIRT6 Antibody (OTI1G3) [Janelia Fluor® 525]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ICC/IF
Clone
OTI1G3
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 525

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-74198AF350
Alexa Fluor 405
NBP2-74198AF405
Alexa Fluor 488
NBP2-74198AF488
Alexa Fluor 532
NBP2-74198AF532
Alexa Fluor 594
NBP2-74198AF594
Alexa Fluor 647
NBP2-74198AF647
Alexa Fluor 700
NBP2-74198AF700
Alexa Fluor 750
NBP2-74198AF750
Biotin
NBP2-74198B
CoraFluor 1
NBP2-74198CL1
DyLight 350
NBP2-74198UV
DyLight 405
NBP2-74198V
DyLight 488
NBP2-74198G
DyLight 550
NBP2-74198R
DyLight 594
NBP2-74198DL594
DyLight 650
NBP2-74198C
DyLight 680
NBP2-74198FR
DyLight 755
NBP2-74198IR
FITC
NBP2-74198F
HRP
NBP2-74198H
Janelia Fluor 549
NBP2-74198JF549
Janelia Fluor 585
NBP2-74198JF585
Janelia Fluor 635
NBP2-74198JF635
Janelia Fluor 646
NBP2-74198JF646
Janelia Fluor 669
NBP2-74198JF669
Unconjugated
NBP2-01310
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-01310
Azide and BSA Free
NBP2-74198
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SIRT6 Antibody (OTI1G3) [Janelia Fluor® 525] Summary

Immunogen
Human recombinant protein fragment corresponding to amino acids 88-352 of human SIRT6(NP_057623) produced in E.coli.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
SIRT6
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for SIRT6 Antibody (OTI1G3) [Janelia Fluor® 525]

  • EC 3.5.1.-
  • NAD-dependent deacetylase sirtuin-6
  • SIR2L6sir2-related protein type 6
  • SIR2-like protein 6
  • sirtuin (silent mating type information regulation 2 homolog) 6 (S. cerevisiae)
  • sirtuin (silent mating type information regulation 2, S. cerevisiae, homolog) 6
  • sirtuin 6
  • sirtuin type 6

Background

Sirtuins regulate epigenetic gene silencing. SIRT6 (Mono-ADP-ribosyltransferase sirtuin-6)--a mouse Sir2 homolog--is a chromatin-associated nuclear ADP-ribosyltransferase protein. It appears to be involved in DNA repair and may also play a role in the ageing process.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

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Bioinformatics

Gene Symbol SIRT6