SH3BP2 Antibody (1E9)

This product is produced by and distributed for Abnova, a company based in Taiwan.

The protein encoded by the SH3BP2 gene has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases , and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism. Multiple transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Showing Publications 1 - 3 of 3.

Publications using H00006452-M01	Applications	Species
Kyoko K, Tomoyuki M, Masanori I et al. SH3BP2 Deficiency Ameliorates Murine Systemic Lupus Erythematosus. Int J Mol Sci. 2021-04-17 [PMID: 33920631]
Kittaka M, Yoshimoto T, Schlosser C et al. Alveolar bone protection by targeting the SH3BP2-SYK axis in osteoclasts. J Bone Miner Res. 2019-10-24 [PMID: 31613396]
Matsumoto Y, La Rose J, Kent OA et al. Reciprocal stabilization of ABL and TAZ regulates osteoblastogenesis through transcription factor RUNX2. J Clin Invest 2016-12-01 [PMID: 27797343]

Array H00006452-M01

• SH3BP2 Antibodies
• SH3BP2 ELISA Kits
• SH3BP2 Lysates
• SH3BP2 Protein