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Serpin A8/Angiotensinogen Antibody

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Immunohistochemistry: Serpin A8/Angiotensinogen Antibody [NBP3-35581] - Immunohistochemistry analysis of paraffin-embedded Human liver cancer using Serpin A8/Angiotensinogen Rabbit pAb at dilution of 1:100 (40x lens). ...read more
Immunohistochemistry: Serpin A8/Angiotensinogen Antibody [NBP3-35581] - Immunohistochemistry analysis of paraffin-embedded Human placenta using Serpin A8/Angiotensinogen Rabbit pAb at dilution of 1:100 (40x lens). ...read more
Western Blot: Serpin A8/Angiotensinogen Antibody [NBP3-35581] - Western blot analysis of various lysates using Serpin A8/Angiotensinogen Rabbit pAb at 1:1000 dilution.Secondary antibody: HRP-conjugated Goat anti-Rabbit ...read more
Immunocytochemistry/ Immunofluorescence: Serpin A8/Angiotensinogen Antibody [NBP3-35581] - Immunofluorescence analysis of HepG2 cells using Serpin A8/Angiotensinogen Rabbit pAb at dilution of 1:200 (40x lens). Secondary ...read more

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

Serpin A8/Angiotensinogen Antibody Summary

Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 35-485 of human Serpin A8/Angiotensinogen (NP_000020.1).

Sequence:
RVYIHPFHLVIHNESTCEQLAKANAGKPKDPTFIPAPIQAKTSPVDEKALQDQLVLVAAKLDTEDKLRAAMVGMLANFLGFRIYGMHSELWGVVHGATVLSPTAVFGTLASLYLGALDHTADRLQAILGVPWKDKNCTSRLDAHKVLSALQAVQGLLVAQGRADSQAQLLLSTVVGVFTAPGLHLKQPFVQGLALYTPVVLPRSLDFTELDVAAEKIDRFMQAVTGWKTGCSLMGASVDSTLAFNTYVHFQ
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
AGT
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Immunocytochemistry/ Immunofluorescence 1:50 - 1:100
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1:50 - 1:100
  • Western Blot 1:500 - 1:1000
Theoretical MW
53 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.3), 50% glycerol
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for Serpin A8/Angiotensinogen Antibody

  • AGT
  • alpha-1 antiproteinase, antitrypsin
  • Angiotensin II
  • angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
  • Angiotensinogen
  • ANHU
  • Aogen
  • FLJ92595
  • FLJ97926
  • PAT
  • pre-angiotensinogen
  • serine (or cysteine) proteinase inhibitor
  • Serpin A8
  • SERPINA8angiotensin I

Background

Angiotensin II is encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol AGT