Serpin A5/Protein C Inhibitor Antibody (OTI2D10) Summary
Immunogen |
Full length human recombinant protein of human SERPINA5(NP_000615) produced in HEK293T cell. |
Isotype |
IgG1 |
Clonality |
Monoclonal |
Host |
Mouse |
Gene |
SERPINA5 |
Purity |
Immunogen affinity purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Flow Cytometry 1:100
- Immunocytochemistry/ Immunofluorescence 1:100
- Immunohistochemistry 1:150
- Immunohistochemistry-Paraffin 1:150
- Western Blot 1:2000
|
Theoretical MW |
45.5 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Packaging, Storage & Formulations
Storage |
Store at -20C. Avoid freeze-thaw cycles. |
Buffer |
PBS (pH 7.3), 1.0% BSA and 50% Glycerol |
Preservative |
0.02% Sodium Azide |
Concentration |
0.75 mg/ml |
Purity |
Immunogen affinity purified |
Alternate Names for Serpin A5/Protein C Inhibitor Antibody (OTI2D10)
Background
PAI-1, PAI-2 and PAI-3 (plasminogen activator inhibitor-1, -2 and -3) are members of the serpin serine proteinase inhibitor family. PAI-1 and PAI-2 regulate uPA (urokinase-type plasminogen activator) and TPA (tissue plasminogen activator), resulting in the inhibition of proteolytic activity. Members of the serpin family generally complex with their target proteinases, then disassociate slowly into cleaved species that fold into stable inactive forms. PAI-1 can fold into the inactive state without cleavage resulting in the latent form of PAI-1. Activity can be restored to the latent form of PAI-1 through denaturation and renaturation. PAI-2 occurs in secreted and cytosolic forms through facultative polypeptide translocation. PAI-3 inhibits plasminogen activators as well as activated protein C. PAI-3 is secreted in plasma, but is also expressed in liver.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Product General Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
Video Protocols
FAQs for Serpin A5/Protein C Inhibitor Antibody (NBP2-01833). (Showing 1 - 2 of 2 FAQ).
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I would like to know if your Serpin A5/Protein C Inhibitor Antibody (2D10) is it the same antibody required for plasma serine protease inhibitor.
- Our Serpin A5/Protein C Inhibitor antibody (2D10) with catalogue number NBP2-01833 was raised against full length recombinant human SERPINA5. SERPINA5 is also known as plasma serine protease inhibitor.
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Can I please have a concentration of NBP2-01833, Serpin A5/Protein C Inhibitor Antibody (2D10) 0.1 ml, lot# A01.
Secondary Antibodies
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Isotype Controls
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