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Seipin/BSCL2 Antibody (1G4)

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Sandwich ELISA: Seipin/BSCL2 Antibody (1G4) [H00026580-M01] - Detection limit for recombinant GST tagged BSCL2 is approximately 0.1ng/ml as a capture antibody.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clone
1G4
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

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Seipin/BSCL2 Antibody (1G4) Summary

Immunogen
BSCL2 (NP_116056, 259 a.a. ~ 357 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. WGGIWPRHRFSLQVNIRKRDNSRKEVQRRISAHQPGPEGQEESTPQSDVTEDGESPEDPSGTEGQLSEEEKPDQQPLSGEEELEPEASDGSGSWEDAAL
Specificity
BSCL2 - Bernardinelli-Seip congenital lipodystrophy 2 (seipin)
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
BSCL2
Purity
IgG purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Sandwich ELISA
  • Western Blot 1:500
Application Notes
Antibody reactive against recombinant protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control.

Reactivity Notes

Human. Other species not tested.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
In 1x PBS, pH 7.4
Preservative
No Preservative
Purity
IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Seipin/BSCL2 Antibody (1G4)

  • Berardinelli-Seip congenital lipodystrophy 2 (seipin)
  • Bernardinelli-Seip congenital lipodystrophy 2 (seipin)
  • Bernardinelli-Seip congenital lipodystrophy type 2 protein
  • BSCL2
  • FLJ16651
  • GNG3LG
  • HMN5
  • MGC4694
  • Seipin
  • spastic paraplegia 17 (Silver syndrome)
  • SPG17

Background

This gene encodes protein seipin, which is located in the endoplasmic reticulum and may be important for lipid droplet morphology. Mutations in this gene have been associated with congenital generalized lipodystrophy type 2 or Berardinelli-Seip syndrome, a rare autosomal recessive disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol BSCL2
Entrez
OMIM
Uniprot