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SCN11A Antibody

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Immunohistochemistry-Paraffin: SCN11A Antibody [NBP1-82600] - Staining of human rectum shows moderate cytoplasmic and membranous positivity in glandular cells.
Immunohistochemistry-Paraffin: SCN11A Antibody [NBP1-82600] - Staining of human rectum shows moderate cytoplasmic and membranous positivity in glandular cells.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

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SCN11A Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: EERNGNLEGEARKTKVQLALDRFRRAFCFVRHTLEHFCHKWCRKQNLPQQKEVAGGCAAQSKDIIPLVME
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SCN11A
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:20 - 1:50
  • Immunohistochemistry-Paraffin 1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
SCN11A Protein (NBP1-82600PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for SCN11A Antibody

  • hNaN
  • NaN
  • NAV1.9
  • Peripheral nerve sodium channel 5
  • PN5
  • SCN11A
  • SCN12A
  • SNS2
  • SNS-2
  • sodium channel, voltage-gated, type XI, alpha polypeptide
  • sodium channel, voltage-gated, type XI, alpha subunit
  • sodium channel, voltage-gated, type XII, alpha
  • voltage-gated sodium channel Nav1.9
  • Voltage-gated sodium channel subunit alpha Nav1.9
  • voltage-gated, type XII, alpha polypeptide

Background

Voltage-gated sodium channels are membrane protein complexes that play a fundamental role in generating and transmitting action potentials in neuronal cells. SCN11A (Sodium channel, voltage-gated, type XI, alpha subunit) mediates the voltage-dependent sodium ion permeability and conductance. It forms the pore of the sodium-selective channel through which sodium ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-resistant sodium channel isoform.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol SCN11A