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SARM1 Antibody

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Western Blot: SARM1 Antibody [NBP3-13023] - Whole cell extract (30 ug) was separated by 7.5% SDS-PAGE, and the membrane was blotted with SARM1 antibody (NBP3-13023) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG ...read more
Immunocytochemistry/ Immunofluorescence: SARM1 Antibody [NBP3-13023] - SARM1 antibody detects SARM1 protein at cytoplasm and nucleus by immunofluorescent analysis.Sample: 293T cells were fixed in 4% paraformaldehyde at ...read more

Product Details

Summary
Reactivity Hu, Dr, Mu, Rt, RMSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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SARM1 Antibody Summary

Description
Centrifuge briefly prior to opening.
Immunogen
Recombinant protein encompassing a sequence within the C-terminus region of human SARM1. The exact sequence is proprietary.
Predicted Species
Mouse (97%), Rat (95%), Rhesus Macaque (98%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SARM1
Purity
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7), 20% Glycerol
Preservative
0.025% Proclin 300
Purity
Antigen Affinity-purified

Alternate Names for SARM1 Antibody

  • KIAA0524SAM domain-containing protein 2
  • SAMD2
  • SAMD2sterile alpha and HEAT/Armadillo motif protein, ortholog of Drosophila
  • SARM1
  • SARMFLJ36296
  • Sterile alpha and Armadillo repeat protein
  • sterile alpha and TIR motif containing 1
  • sterile alpha and TIR motif-containing protein 1
  • Sterile alpha motif domain-containing protein 2
  • Tir-1 homolog

Background

Toll-like receptors (TLRs) play an essential role in the detection and elimination of invading microbes. They are type-1 transmembrane receptors, containing extracellular leucine rich repeats and an intracellular Toll/interleukin-1 receptor (TIR) domain. Upon stimulation, these receptors interact with specific TIR domain-containing adaptor proteins. Five such adaptors have been discovered to date, MyD88, Mal (MyD88 adaptor-like)/TIRAP (TIR domain-containing adaptor protein), Trif (TIR-domain-containing adaptor inducing interferon-beta), TRAM (Trif-related adaptor molecule) and SARM (SAM and ARM-containing protein). Different TLRs use different combinations of these adaptors, leading to the activation of common and unique pathways involved in the elimination of the invading microbe.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Array NBP3-13023

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Bioinformatics

Gene Symbol SARM1