Have any of your MRP8 antibodies been tested for use in neutralization, or blocking assays, on human samples?

Name: S100A8 Antibody (335806)
Brand: Novus Biologicals
SKU: MAB3059
Price: 479 USD

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Accepted Answer

Unfortunately at this time we have not tested, or received customer feedback on our MMP8 antibodies for use in blocking or neutralizing assays. If you were planning on testing any of our MMP8 antibodies for neutralizing or blocking capabilities, we would recommend our Innovator’s Reward Program. Under the terms of this program we would be happy to provide a credit for a free vial in exchange for new data on this previously untested or reported application. Please submit this data in the form of an online review. Additional Innovators Reward Program information can be found using this link.

At	=	A. thaliana	SyHa	=	Golden Syrian Hamster
All	=	All Species	Ha	=	Hamster
An	=	Animal	Hu	=	Human
ArHa	=	Armenian Hamster	I	=	Insect
Av	=	Avian	Ll	=	Llama
Bb	=	Baboon	Ma	=	Mammal
Ba	=	Bacteria	Mk	=	Monkey
Bv	=	Bovine	Mu	=	Mouse
Ca	=	Canine	Multi	=	Multi-species
Ce	=	C. Elegans	NA	=	Non-species specific
Ch	=	Chicken	Or	=	Orangutan
ChHa	=	Chinese Hamster	Pl	=	Plant
Cm	=	Cynomolgus Monkey	Pm	=	Primate
Do	=	Donkey	Po	=	Porcine
Dr	=	Drosophilia	Rb	=	Rabbit
Ec	=	E. Coli	Rt	=	Rat
Eq	=	Equine	RM	=	Rhesus Macaque
Fe	=	Feline	Sh	=	Sheep
Ft	=	Ferret	Vb	=	Vertebrate
Fi	=	Fish	Vi	=	Virus
Fu	=	Fungi	Xp	=	Xenopus
Ge	=	Gerbil	Ye	=	Yeast
GP	=	Guinea Pig	Ze	=	Zebrafish
Gt	=	Goat

Reactivity	MuSpecies Glossary
Applications	WB, ICC/IF
Clone	335806
Clonality	Monoclonal
Host	Rat
Conjugate	Unconjugated
Concentration	LYOPH

Catalog# & Formulation	Size	Price
Carrier Free MAB3059-SP

Immunogen	E. coli-derived recombinant mouse S100A8 Met1-Glu89 (predicted) Accession # P27005
Specificity	Detects mouse S100A8 in direct ELISAs and Western blots. In direct ELISAs and Western blots, 40% cross-reactivity with recombinant human (rh) S100A8 is observed and no cross-reactivity with recombinant mouse (rm) S100A4, rmS100A9, rmS100A10, rmS100A11, rhS100B, or rhS100P is observed.
Source	N/A
Isotype	IgG2b
Clonality	Monoclonal
Host	Rat
Gene	S100A8
Purity Statement	Protein A or G purified from hybridoma culture supernatant
Innovator's Reward	Test in a species/application not listed above to receive a full credit towards a future purchase. Learn about the Innovator's Reward

Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer	Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative	No Preservative
Concentration	LYOPH
Reconstitution Instructions	Reconstitute at 0.5 mg/mL in sterile PBS.

S100A8 Antibody (335806)

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Publications for S100A8 Antibody (MAB3059)(13)

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Bioinformatics

Publications using MAB3059	Applications	Species
Lindquist, KA;Shein, SA;Hovhannisyan, AH;Mecklenburg, J;Zou, Y;Lai, Z;Tumanov, AV;Akopian, AN; Associations of tissue damage induced inflammatory plasticity in masseter muscle with the resolution of chronic myalgia Scientific reports 2023-12-12 [PMID: 38086903] (Immunohistochemistry, Mouse, Transgenic Mouse)	Immunohistochemistry	Mouse, Transgenic Mouse
Zhao, N;Kabotyanski, EB;Saltzman, AB;Malovannaya, A;Yuan, X;Reineke, LC;Lieu, N;Gao, Y;Pedroza, DA;Calderon, SJ;Smith, AJ;Hamor, C;Safari, K;Savage, S;Zhang, B;Zhou, J;Solis, LM;Hilsenbeck, SG;Fan, C;Perou, CM;Rosen, JM; Targeting EIF4A triggers an interferon response to synergize with chemotherapy and suppress triple-negative breast cancer bioRxiv : the preprint server for biology 2023-09-28 [PMID: 37808840] (IHC, Human)	IHC	Human
Darya Pavlenko, Zeynep Todurga Todurga Seven, Lauren Bystrom, Anika Markan, Rebecca Verpile, Hirotake Ishida et al. Crisaborole Inhibits Itch and Pain by Preventing Neutrophil Infiltration in a Mouse Model of Atopic Dermatitis Acta Dermato-Venereologica 8/22/2023 [PMID: 37605895]
Mahnaz Janghorban, Yuchen Yang, Na Zhao, Clark Hamor, Tuan M. Nguyen, Xiang H.-F. Zhang et al. Single-Cell Analysis Unveils the Role of the Tumor Immune Microenvironment and Notch Signaling in Dormant Minimal Residual Disease Cancer Research 3/1/2022 [PMID: 34965936]
Z Shi, Y Mori-Akiya, W Du, R Fultz, Y Zhao, W Ruan, S Venable, MA Engevik, J Versalovic Loss of H2R signaling disrupts neutrophil homeostasis and promotes inflammation-associated colonic tumorigenesis in mice Cellular and Molecular Gastroenterology and Hepatology, 2021-11-13;0(0):. 11/13/2021 [PMID: 34781022]
VC Sinha, AL Rinkenbaug, M Xu, X Zhou, X Zhang, S Jeter-Jone, J Shao, Y Qi, JA Zebala, DY Maeda, F McAllister, H Piwnica-Wo Single-cell evaluation reveals shifts in the tumor-immune niches that shape and maintain aggressive lesions in the breast Nature Communications, 2021-08-18;12(1):5024. 2021-08-18 [PMID: 34408137] (ICC, Mouse)	ICC	Mouse
Laura M. Davison, Andres A. Alberto, Hardik A. Dand, Emma J. Keller, Madeline Patt, Ayesha Khan et al. S100a9 Protects Male Lupus-Prone NZBWF1 Mice From Disease Development Frontiers in Immunology 6/17/2021 [PMID: 34220829]
S. J. Kim, S. Garcia-Recio, C. J. Creighton, C. M. Perou, J. M. Rosen Alterations in Wnt- and/or STAT3 signaling pathways and the immune microenvironment during metastatic progression Oncogene 8/1/2019 [PMID: 31289359]
N Makthal, K Nguyen, H Do, M Gavagan, P Chandrangs, JD Helmann, RJ Olsen, M Kumaraswam A Critical Role of Zinc Importer AdcABC in Group A Streptococcus-Host Interactions During Infection and Its Implications for Vaccine Development EBioMedicine, 2017-06-02;0(0):. 2017-06-02 [PMID: 28596134] (Western Blot, Mouse)	Western Blot	Mouse
Sekimoto R, Fukuda S, Maeda N, Tsushima Y, Matsuda K, Mori T, Nakatsuji H, Nishizawa H, Kishida K, Kikuta J, Maijima Y, Funahashi T, Ishii M, Shimomura I Visualized macrophage dynamics and significance of S100A8 in obese fat. Proc Natl Acad Sci U S A, 2015-04-06;112(16):E2058-66. 2015-04-06 [PMID: 25848057] (Mouse)		Mouse
Dessing , Mark C, Tammaro , Alessand, Pulskens , Wilco P, Teske , Gwendoli, Butter , Loes M, Claessen , Nike, van Eijk , Marco, van der Poll , Tom, Vogl , Thomas, Roth , Johannes, Florquin , Sandrine, Leemans , Jaklien The calcium-binding protein complex S100A8/A9 has a crucial role in controlling macrophage-mediated renal repair following ischemia/reperfusion. Kidney Int, 2014-06-18;87(1):85-94. 2014-06-18 [PMID: 24940802] (IHC, Mouse)	IHC	Mouse
Yano , Junko, Kolls , Jay K, Happel , Kyle I, Wormley , Floyd, Wozniak , Karen L, Fidel , Paul L J The Acute Neutrophil Response Mediated by S100 Alarmins during Vaginal Candida Infections Is Independent of the Th17-Pathway. PLoS ONE, 2012-09-25;7(9):e46311. 2012-09-25 [PMID: 23050010] (ELISA Development, IHC-Fr, Mouse)	ELISA Development, IHC-Fr	Mouse
Dessing MC, Butter LM, Teske GJ S100A8/A9 is not involved in host defense against murine urinary tract infection. PLoS ONE, 2010-10-14;5(10):e13394. 2010-10-14 [PMID: 20976233] (IHC-P, Mouse)	IHC-P	Mouse
Show All 13 Publications. Collapse Publications.

Gene Symbol	S100A8
Uniprot	P27005()