ROR gamma/RORC/NR1F3 Antibody (4G419) [DyLight 650] Summary
Description |
This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet. |
Immunogen |
A portion of amino acids 1-50 of human ROR gamma was used as the immunogen. |
Predicted Species |
Primate (96%). Backed by our 100% Guarantee. |
Isotype |
IgG1 Kappa |
Clonality |
Monoclonal |
Host |
Mouse |
Gene |
RORC |
Purity |
Immunogen affinity purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Flow Cytometry
- Western Blot
|
Application Notes |
Optimal dilution of this antibody should be experimentally determined. |
Reactivity Notes
Rat reactivity reported in scientific literature (PMID: 22110656).
Packaging, Storage & Formulations
Storage |
Store at 4C in the dark. |
Buffer |
50mM Sodium Borate |
Preservative |
0.05% Sodium Azide |
Purity |
Immunogen affinity purified |
Notes
DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.
Alternate Names for ROR gamma/RORC/NR1F3 Antibody (4G419) [DyLight 650]
Background
ROR gamma/RORC/NR1F3, aka RAR Orphan Receptor gamma, is a Nuclear Receptor 1 Thyroid Hormone-Like receptor containing a short A-T rich sequence follow by a single core motif half-site 5'-AGGTCA-3'. RORC is a key regulator of thymopoiesis, bone metabolism, T-cell apoptosis, and lymphoid organogenesis. NR1F3 regulates intrinsic transcriptional functions. Unlike other major nuclear receptors, RORC binds as a monomer to hormone response elements and is documented in mouse thymus, adipose, bone, skeletal muscle, liver, kidney, and human skeletal muscle. An N-terminal isoform of ROR gamma, ROR gamma T, inhibits Fas ligand expression and cytokine secretion in immature thymocytes.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Publications for ROR gamma/RORC/NR1F3 Antibody (NBP2-24449C) (0)
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Product General Protocols
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Video Protocols
FAQs for ROR gamma/RORC/NR1F3 Antibody (NBP2-24449C). (Showing 1 - 3 of 3 FAQ).
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Does ROR gamma/RORC/NR1F3 antibodies comes in lyophilized form?
- Yes, we have 3 RORC antibodies delivere in lyophilized form: MAB61091, MAB61092, MAB6109.
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What the theoretical molecular weight for ROR gamma/RORC/NR1F3 antibodies?
- The TMW of ROR gamma/RORC/NR1F3 antibodies is approximately 56 - 60.
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What is the immunogen sequence of this ROR gamma/RORC/NR1F3 antibody?
- A sequence from amino acids 1 - 50 of Human ROR gamma.
Secondary Antibodies
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Isotype Controls
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