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ROR gamma/RORC/NR1F3 Antibody (4G419) [Allophycocyanin]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, Flow
Clone
4G419
Clonality
Monoclonal
Host
Mouse
Conjugate
Allophycocyanin

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-24449AF350
Alexa Fluor 405
NBP2-24449AF405
Alexa Fluor 488
NBP2-24449AF488
Alexa Fluor 532
NBP2-24449AF532
Alexa Fluor 594
NBP2-24449AF594
Alexa Fluor 647
NBP2-24449AF647
Alexa Fluor 700
NBP2-24449AF700
Alexa Fluor 750
NBP2-24449AF750
Allophycocyanin
NBP2-24451
Biotin
NBP2-24449B
DyLight 350
NBP2-24449UV
DyLight 405
NBP2-24449V
DyLight 488
NBP2-24449G
DyLight 550
NBP2-24449R
DyLight 594
NBP2-24449DL594
DyLight 650
NBP2-24449C
DyLight 680
NBP2-24449FR
DyLight 755
NBP2-24449IR
FITC
NBP2-24449F
FITC
NBP2-24447
HRP
NBP2-24449H
Janelia Fluor 549
NBP2-24449JF549
Janelia Fluor 646
NBP2-24449JF646
PE
NBP2-24452
PE
NBP2-24449PE
PerCP
NBP2-24449PCP
Unconjugated
NBP2-24449
mFluor Violet 450 SE
NBP2-24449MFV450
mFluor Violet 500 SE
NBP2-24449MFV500
mFluor Violet 610 SE
NBP2-24449MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-24449
BSA Free
NBP2-24449
BSA Free
NBP2-24449SS
Azide and BSA Free
NBP2-80930
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ROR gamma/RORC/NR1F3 Antibody (4G419) [Allophycocyanin] Summary

Immunogen
A portion of amino acids 1-50 of human ROR gamma was used as the immunogen.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
RORC
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Rat reactivity reported in scientific literature (PMID: 22110656).

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Alternate Names for ROR gamma/RORC/NR1F3 Antibody (4G419) [Allophycocyanin]

  • MGC129539
  • NR1F3
  • Nuclear receptor ROR gamma
  • Nuclear receptor ROR-gamma
  • Nuclear receptor RZR gamma
  • Nuclear receptor RZR-gamma
  • Nuclear receptor subfamily 1 group F member 3
  • RAR-Related Orphan Nuclear Receptor Variant 2
  • RAR-related orphan receptor C
  • RAR-related orphan receptor gamma
  • retinoic acid-binding receptor gamma
  • retinoid-related orphan receptor gamma
  • Retinoid-related orphan receptor-gamma
  • ROR gamma
  • RORC
  • RORG
  • RORGMGC129539
  • RZRG
  • RZRGRZR-GAMMA
  • TOR

Background

ROR gamma/RORC/NR1F3, aka RAR Orphan Receptor gamma, is a Nuclear Receptor 1 Thyroid Hormone-Like receptor containing a short A-T rich sequence follow by a single core motif half-site 5'-AGGTCA-3'. RORC is a key regulator of thymopoiesis, bone metabolism, T-cell apoptosis, and lymphoid organogenesis. NR1F3 regulates intrinsic transcriptional functions. Unlike other major nuclear receptors, RORC binds as a monomer to hormone response elements and is documented in mouse thymus, adipose, bone, skeletal muscle, liver, kidney, and human skeletal muscle. An N-terminal isoform of ROR gamma, ROR gamma T, inhibits Fas ligand expression and cytokine secretion in immature thymocytes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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NBP2-24449APC
ROR gamma/RORC/NR1F3 Antibody (4G419) [Allophycocyanin]
Species: Hu, Mu, Rt
Applications: WB, Flow
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FAQs for ROR gamma/RORC/NR1F3 Antibody (NBP2-24449APC). (Showing 1 - 2 of 2 FAQ).

  1. Does ROR gamma/RORC/NR1F3 antibodies comes in lyophilized form?
    • Yes, we have 3 RORC antibodies delivere in lyophilized form: MAB61091, MAB61092, MAB6109.
  2. What the theoretical molecular weight for ROR gamma/RORC/NR1F3 antibodies?
    • The TMW of ROR gamma/RORC/NR1F3 antibodies is approximately 56 - 60.

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Bioinformatics

Gene Symbol RORC