| Goeckel, ME;Lee, J;Levitas, A;Colijn, S;Mun, G;Burton, Z;Chintalapati, B;Yin, Y;Abello, J;Stratman, A; CXCR3-CXCL11 signaling restricts angiogenesis and promotes pericyte recruitment bioRxiv : the preprint server for biology 2023-09-17 [PMID: 37745440] (Cell Culture, Human) |
Cell Culture |
Human |
| AA Almad, L Garcia, A Takanohash, A Gagne, W Yang, J Ann McGuir, D French, A Vanderver Generation of three induced Pluripotent Stem Cell lines from individuals with Hypomyelination with Atrophy of Basal Ganglia and Cerebellum caused by a c.745G>A (p.D249N) autosomal dominant mutation in TUBB4A Stem Cell Research, 2023-03-26;69(0):103083. 2023-03-26 [PMID: 37003180] (Bioassay, Human) |
Bioassay |
Human |
| JR James, J Curd, JC Ashworth, M Abuhantash, M Grundy, CH Seedhouse, KP Arkill, AJ Wright, CLR Merry, A Thompson Hydrogel-Based Pre-Clinical Evaluation of Repurposed FDA-Approved Drugs for AML International Journal of Molecular Sciences, 2023-02-20;24(4):. 2023-02-20 [PMID: 36835644] (Bioassay, Human) |
Bioassay |
Human |
| L Feige, T Kozaki, G Dias de Me, V Guillemot, F Larrous, F Ginhoux, H Bourhy Susceptibilities of CNS Cells towards Rabies Virus Infection Is Linked to Cellular Innate Immune Responses Viruses, 2022-12-29;15(1):. 2022-12-29 [PMID: 36680128] (Bioassay, Human) |
Bioassay |
Human |
| S Takase, T Hiroyama, F Shirai, Y Maemoto, A Nakata, M Arata, S Matsuoka, T Sonoda, H Niwa, S Sato, T Umehara, M Shirouzu, Y Nishigaya, T Sumiya, N Hashimoto, R Namie, M Usui, T Ohishi, SI Ohba, M Kawada, Y Hayashi, H Harada, T Yamaguchi, Y Shinkai, Y Nakamura, M Yoshida, A Ito A specific G9a inhibitor unveils BGLT3 lncRNA as a universal mediator of chemically induced fetal globin gene expression Nature Communications, 2023-01-12;14(1):23. 2023-01-12 [PMID: 36635268] (Bioassay, Human) |
Bioassay |
Human |
| X Wang, S Cooper, HE Broxmeyer, R Kapur Transient regulation of RNA methylation in human hematopoietic stem cells promotes their homing and engraftment Leukemia, 2022-12-02;0(0):. 2022-12-02 [PMID: 36460765] (Cell Culture, Human) |
Cell Culture |
Human |
| PY Su, W Lee, J Zernant, SH Tsang, T Nagasaki, B Corneo, R Allikmets Establishment of the iPSC line CUIMCi005-A from a patient with Stargardt disease for retinal organoid culture Oncogene, 2022-11-14;65(0):102973. 2022-11-14 [PMID: 36455383] (Bioassay, Human) |
Bioassay |
Human |
| X Liu, N Sato, T Yabushita, J Li, Y Jia, M Tamura, S Asada, T Fujino, T Fukushima, T Yonezawa, Y Tanaka, T Fukuyama, A Tsuchiya, S Shikata, H Iwamura, C Kinouchi, K Komatsu, S Yamasaki, T Shibata, AT Sasaki, J Schibler, M Wunderlich, E O'Brien, B Mizukawa, JC Mulloy, Y Sugiura, H Takizawa, T Shibata, K Miyake, T Kitamura, S Goyama IMPDH inhibition activates TLR-VCAM1 pathway and suppresses the development of MLL-fusion leukemia Embo Molecular Medicine, 2022-12-01;0(0):e15631. 2022-12-01 [PMID: 36453131] (Cell Culture, Human) |
Cell Culture |
Human |
| Kunitomi A, Hirohata R, Arreola V, Osawa M, Kato T, Nomura M, Kawaguchi J, Hara H, Kusano K, Takashima Y, Takahashi K, Fukuda K, Takasu N, Yamanaka S Improved Sendai viral system for reprogramming to naive pluripotency. Cell Rep Methods, 2022-10-17;2(11):100317. 2022-10-17 [PMID: 36447645] (Bioassay, Human) |
Bioassay |
Human |
| N Vilaplana-, V Cuminetti, R Almaghrabi, G Papatzikas, AK Rout, M Jeeves, E González, Y Alyahyawi, A Cunningham, A Erdem, F Schnütgen, M Raghavan, S Potluri, JB Cazier, JJ Schuringa, MAC Reed, L Arranz, UL Günther, P Garcia Crosstalk between AML and stromal cells triggers acetate secretion through the metabolic rewiring of stromal cells Elife, 2022-09-02;11(0):. 2022-09-02 [PMID: 36052997] (Bioassay, Human) |
Bioassay |
Human |
| YS Michaels, JM Edgar, MC Major, EL Castle, C Zimmerman, T Yin, A Hagner, C Lau, HH Hsu, MI Ibañez-Rio, LJ Durland, DJHF Knapp, PW Zandstra DLL4 and VCAM1 enhance the emergence of T cell-competent hematopoietic progenitors from human pluripotent stem cells Science Advances, 2022-08-24;8(34):eabn5522. 2022-08-24 [PMID: 36001668] (Bioassay, Human) |
Bioassay |
Human |
| BF Vahsen, E Gray, A Candalija, KML Cramb, J Scaber, R Dafinca, A Katsikoudi, Y Xu, L Farrimond, R Wade-Marti, WS James, MR Turner, SA Cowley, K Talbot Human iPSC co-culture model to investigate the interaction between microglia and motor neurons Scientific Reports, 2022-07-23;12(1):12606. 2022-07-23 [PMID: 35871163] (Bioassay, Human) |
Bioassay |
Human |
| IB Kim, T Lee, J Lee, J Kim, S Lee, IG Koh, JH Kim, JY An, H Lee, WK Kim, YS Ju, Y Cho, SJ Yu, SA Kim, M Oh, DW Han, E Kim, JK Choi, HJ Yoo, JH Lee Non-coding de novo mutations in chromatin interactions are implicated in autism spectrum disorder Oncogene, 2022-07-15;0(0):. 2022-07-15 [PMID: 35840799] (Bioassay, Human) |
Bioassay |
Human |
| S Wahlen, F Matthijsse, W Van Loocke, S Taveirne, L Kiekens, E Persyn, E Van Ammel, Z De Vos, S De Munter, P Matthys, F Van Nieuwe, T Taghon, B Vandekerck, P Van Vlierb, G Leclercq The transcription factor RUNX2 drives the generation of human NK cells and promotes tissue residency Elife, 2022-07-06;11(0):. 2022-07-06 [PMID: 35793229] (Bioassay, Human) |
Bioassay |
Human |
| L Liu, A Vujovic, NP Deshpande, S Sathe, G Anande, HTT Chen, J Xu, MD Minden, GW Yeo, A Unnikrishn, KJ Hope, Y Lu The splicing factor RBM17 drives leukemic stem cell maintenance by evading nonsense-mediated decay of pro-leukemic factors Nature Communications, 2022-07-04;13(1):3833. 2022-07-04 [PMID: 35781533] (Bioassay, Human) |
Bioassay |
Human |
| BA Krishna, AB Wass, EA Murphy, CM O'Connor Design of a US28 ORF Deletion Virus in a Temperature-Sensitive Cytomegalovirus Strain Fails to Promote Lytic Replication in Hematopoietic Cells Viruses, 2022-06-12;14(6):. 2022-06-12 [PMID: 35746751] (Bioassay, Human) |
Bioassay |
Human |
| Q Lian, K Zhang, Z Zhang, F Duan, L Guo, W Luo, BW Mok, A Thakur, X Ke, P Motallebne, V Nicolaescu, J Chen, CY Ma, X Zhou, S Han, T Han, W Zhang, AY Tan, T Zhang, X Wang, D Xu, J Xiang, A Xu, C Liao, FP Huang, YW Chen, J Na, G Randall, HF Tse, Z Chen, Y Chen, HJ Chen Differential effects of macrophage subtypes on SARS-CoV-2 infection in a human pluripotent stem cell-derived model Nature Communications, 2022-04-19;13(1):2028. 2022-04-19 [PMID: 35440562] (Bioassay, Human) |
Bioassay |
Human |
| Y Liu, Y Liu, Y Jia, J Lv, D Sun, Y Yin, N Liu, B Su, G Sun Generation of an induced pluripotent stem cell (iPSC) line from a diabetic patient with glucagon receptor (GCGR) p.W83X mutation Stem Cell Research, 2022-03-11;61(0):102745. 2022-03-11 [PMID: 35381520] (Bioassay, Human) |
Bioassay |
Human |
| AV Jacobsen, CL Pierotti, KN Lowes, AE Au, Y Zhang, N Etemadi, C Fitzgibbon, WJA Kersten, AL Samson, MF van Delft, DCS Huang, HJ Sabroux, G Lessene, J Silke, JM Murphy The Lck inhibitor, AMG-47a, blocks necroptosis and implicates RIPK1 in signalling downstream of MLKL Cell Death & Disease, 2022-04-01;13(4):291. 2022-04-01 [PMID: 35365636] (Cell Culture, Human) |
Cell Culture |
Human |
| G Iannello, A Patel, D Sirabella, B Corneo, VV Thaker Derivation and characterization of the induced pluripotent stem cell line CUIMCi004-A from a patient with a novel frameshift variant in exon 18a of OCRL Stem Cell Research, 2021-12-23;59(0):102635. 2021-12-23 [PMID: 35074682] (Bioassay, Human) |
Bioassay |
Human |
| Y Dong, X Li, W Fu, X Tian, G Guo, Y Peng, Y Zhai, J Zhao, Z Ding, X Zhao, J Dong Generation of an iPSC line (ZZUNEUi021-A) from a hypertrophic cardiomyopathy patient with TNNT2 mutation Stem Cell Research, 2021-12-11;58(0):102622. 2021-12-11 [PMID: 34929444] (Bioassay, Human) |
Bioassay |
Human |
| AF de Souza, FF Bressan, NCG Pieri, RC Botigelli, T Revay, SK Haddad, DT Covas, ES Ramos, WA King, FV Meirelles Generation of Primordial Germ Cell-like Cells from iPSCs Derived from Turner Syndrome Patients Cells, 2021-11-10;10(11):. 2021-11-10 [PMID: 34831322] |
|
|
| C Tipgomut, A Khuhapinan, MC Wilson, S Poldee, KJ Heesom, C Metheetrai, O Sripichai, C Mitrpant, J Frayne, K Trakarnsan MTAP-related increased erythroblast proliferation as a mechanism of polycythaemia vera Scientific Reports, 2021-11-18;11(1):22483. 2021-11-18 [PMID: 34795367] (Bioassay, Human) |
Bioassay |
Human |
| GB Schwartz, H Kubo, MM Laronda Generation of two human induced pluripotent stem cell lines from a patient with complete androgen insensitivity syndrome with a hemizygous single nucleotide variant in the androgen receptor (AR) gene Stem Cell Research, 2021-06-30;55(0):102441. 2021-06-30 [PMID: 34233262] (Bioassay, Human) |
Bioassay |
Human |
| G Iannello, A Patel, D Sirabella, B Corneo, V Thaker Generation of the iPSC line CUIMCi003-A derived from a patient with severe early onset obesity Stem Cell Research, 2021-06-21;54(0):102432. 2021-06-21 [PMID: 34214899] (Bioassay, Human) |
Bioassay |
Human |
| S Simón Serr, M Tavecchio, A Grönberg, W Sime, M Jemaà, S Moss, MA Gregory, P Gallay, E Elmér, MJ Hansson, R Massoumi Novel Cyclophilin Inhibitor Decreases Cell Proliferation and Tumor Growth in Models of Hepatocellular Carcinoma Cancers, 2021-06-18;13(12):. 2021-06-18 [PMID: 34207224] (Bioassay, Human) |
Bioassay |
Human |
| GA Newby, JS Yen, KJ Woodard, T Mayuranath, CR Lazzarotto, Y Li, H Sheppard-T, SN Porter, Y Yao, K Mayberry, KA Everette, Y Jang, CJ Podracky, E Thaman, C Lechauve, A Sharma, JM Henderson, MF Richter, KT Zhao, SM Miller, T Wang, LW Koblan, AP McCaffrey, JF Tisdale, TA Kalfa, SM Pruett-Mil, SQ Tsai, MJ Weiss, DR Liu Base editing of haematopoietic stem cells rescues sickle cell disease in mice Nature, 2021-06-02;0(0):. 2021-06-02 [PMID: 34079130] (Bioassay, Human) |
Bioassay |
Human |
| J Borsoi, M Morato-Mar, F de Araújo, L Assis Pere, LE Farinha-Ar, R Delgado Sa, AB Alvarez Pe, L Veiga Pere Generation of two human induced pluripotent stem cell (hiPSC) lines derived from unrelated Marfan Syndrome patients Stem Cell Research, 2021-05-25;54(0):102407. 2021-05-25 [PMID: 34062330] (Bioassay, Human) |
Bioassay |
Human |
| S Matsuo, Y Nishinaka-, Y Kazuki, M Oshimura, T Nakahata, A Niwa, MK Saito Pluripotent stem cell model of early hematopoiesis in Down syndrome reveals quantitative effects of short-form GATA1 protein on lineage specification PLoS ONE, 2021-03-29;16(3):e0247595. 2021-03-29 [PMID: 33780474] (Bioassay, Human) |
Bioassay |
Human |
| S Jung, E Appleton, M Ali, GM Church, A Del Sol A computer-guided design tool to increase the efficiency of cellular conversions Nature Communications, 2021-03-12;12(1):1659. 2021-03-12 [PMID: 33712564] (Bioassay, Human) |
Bioassay |
Human |
| AL Kennedy, KC Myers, J Bowman, CJ Gibson, ND Camarda, E Furutani, GM Muscato, RH Klein, K Ballotti, S Liu, CE Harris, A Galvin, M Malsch, D Dale, JM Gansner, TA Nakano, A Bertuch, A Vlachos, JM Lipton, P Castillo, J Connelly, J Churpek, JR Edwards, N Hijiya, RH Ho, I Hofmann, JN Huang, S Keel, A Lamble, BW Lau, M Norkin, E Stieglitz, W Stock, K Walkovich, S Boettcher, C Brendel, MD Fleming, SM Davies, EA Weller, C Bahl, SL Carter, A Shimamura, RC Lindsley Distinct genetic pathways define pre-malignant versus compensatory clonal hematopoiesis in Shwachman-Diamond syndrome Nature Communications, 2021-02-26;12(1):1334. 2021-02-26 [PMID: 33637765] (Bioassay, Human) |
Bioassay |
Human |
| T Wang, AR Pine, AG Kotini, H Yuan, L Zamparo, DT Starczynow, C Leslie, EP Papapetrou Sequential CRISPR gene editing in human iPSCs charts the clonal evolution of myeloid leukemia and identifies early disease targets Cell Stem Cell, 2021-02-10;0(0):. 2021-02-10 [PMID: 33571445] (Bioassay, Human) |
Bioassay |
Human |
| P Gonzalez-M, M Romano, H Yan, R Deshmukh, J Papoin, L Oburoglu, M Daumur, AS Dumé, I Phadke, C Mongellaz, X Qu, PN Bories, M Fontenay, X An, V Dardalhon, M Sitbon, VS Zimmermann, PG Gallagher, S Tardito, L Blanc, N Mohandas, N Taylor, S Kinet An IDH1-vitamin C crosstalk drives human erythroid development by inhibiting pro-oxidant mitochondrial metabolism Cell Reports, 2021-02-02;34(5):108723. 2021-02-02 [PMID: 33535038] (Bioassay, Human) |
Bioassay |
Human |
| S Chen, L Yang, B Nilsson-Pa, Y Han, F Jaffré, J Zhu, P Wang, T Zhang, D Redmond, S Houghton, R Møller, D Hoagland, S Horiuchi, J Acklin, J Lim, Y Bram, C Richardson, V Chandar, A Borczuk, Y Huang, J Xiang, D Ho, R Schwartz, B tenOever, T Evans SARS-CoV-2 Infected Cardiomyocytes Recruit Monocytes by Secreting CCL2 Res Sq, 2020-11-17;0(0):. 2020-11-17 [PMID: 33236003] (Bioassay, Human) |
Bioassay |
Human |
| K Trakarnsan, C Tipgomut, C Metheetrai, M Wattanapan, A Khuhapinan, S Poldee, R Kurita, Y Nakamura, C Srisawat, J Frayne Generation of an immortalised erythroid cell line from haematopoietic stem cells of a haemoglobin E/&beta-thalassemia patient Sci Rep, 2020-10-08;10(1):16798. 2020-10-08 [PMID: 33033327] (Bioassay, Human) |
Bioassay |
Human |
| R Leylek, M Alcántara-, JM Granja, M Chavez, K Perez, OR Diaz, R Li, AT Satpathy, HY Chang, J Idoyaga Chromatin Landscape Underpinning Human Dendritic Cell Heterogeneity Cell Rep, 2020-09-22;32(12):108180. 2020-09-22 [PMID: 32966789] (Bioassay, Human) |
Bioassay |
Human |
| S Riccetti, A Sinigaglia, G Desole, N Nowotny, M Trevisan, L Barzon Modelling West Nile Virus and Usutu Virus Pathogenicity in Human Neural Stem Cells Viruses, 2020-08-12;12(8):. 2020-08-12 [PMID: 32806715] (Bioassay, Human) |
Bioassay |
Human |
| BA Krishna, AB Wass, CM O'Connor Activator protein-1 transactivation of the major immediate early locus is a determinant of cytomegalovirus reactivation from latency Proc. Natl. Acad. Sci. U.S.A., 2020-08-11;117(34):20860-20867. 2020-08-11 [PMID: 32788362] (Bioassay, Human) |
Bioassay |
Human |
| N Thornton, V Karamatic, L Tilley, CA Green, CL Tay, RE Griffiths, BK Singleton, F Spring, P Walser, AG Alattar, B Jones, R Laundy, JR Storry, M Möller, L Wall, R Charlewood, CM Westhoff, C Lomas-Fran, V Yahalom, U Feick, A Seltsam, B Mayer, ML Olsson, DJ Anstee Disruption of the tumour-associated EMP3 enhances erythroid proliferation and causes the MAM-negative phenotype Nat Commun, 2020-07-16;11(1):3569. 2020-07-16 [PMID: 32678083] (Bioassay, Human) |
Bioassay |
Human |
| L Yang, Y Han, BE Nilsson-Pa, V Gupta, P Wang, X Duan, X Tang, J Zhu, Z Zhao, F Jaffré, T Zhang, TW Kim, O Harschnitz, D Redmond, S Houghton, C Liu, A Naji, G Ciceri, S Guttikonda, Y Bram, DT Nguyen, M Cioffi, V Chandar, DA Hoagland, Y Huang, J Xiang, H Wang, D Lyden, A Borczuk, HJ Chen, L Studer, FC Pan, DD Ho, BR tenOever, T Evans, RE Schwartz, S Chen A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids Cell Stem Cell, 2020;27(1):125-136.e7. 2020 [PMID: 32579880] (Bioassay, Human) |
Bioassay |
Human |
| L Yang, Y Han, BE Nilsson-Pa, V Gupta, P Wang, X Duan, X Tang, J Zhu, Z Zhao, F Jaffré, T Zhang, TW Kim, O Harschnitz, D Redmond, S Houghton, C Liu, A Naji, G Ciceri, S Guttikonda, Y Bram, DT Nguyen, M Cioffi, V Chandar, DA Hoagland, Y Huang, J Xiang, H Wang, D Lyden, A Borczuk, HJ Chen, L Studer, FC Pan, DD Ho, BR tenOever, T Evans, RE Schwartz, S Chen A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids Cell Stem Cell, 2020-06-19;27(1):125-136.e7. 2020-06-19 [PMID: 32579880] (Bioassay, Human) |
Bioassay |
Human |
| PR Norden, Z Sun, GE Davis Control of endothelial tubulogenesis by Rab and Ral GTPases, and apical targeting of caveolin-1-labeled vacuoles PLoS ONE, 2020-06-22;15(6):e0235116. 2020-06-22 [PMID: 32569321] (Bioassay, Human) |
Bioassay |
Human |
| X Xiao, P Liu, D Li, Z Xia, P Wang, X Zhang, M Liu, L Liao, B Jiao, R Ren Combination therapy of BCR-ABL-positive B cell acute lymphoblastic leukemia by tyrosine kinase inhibitor dasatinib and c-JUN N-terminal kinase inhibition J Hematol Oncol, 2020-06-18;13(1):80. 2020-06-18 [PMID: 32552902] (Bioassay, Human) |
Bioassay |
Human |
| J Wesely, AG Kotini, F Izzo, H Luo, H Yuan, J Sun, M Georgomano, A Zviran, AG Deslaurier, N Dusaj, SD Nimer, C Leslie, DA Landau, MG Kharas, EP Papapetrou Acute Myeloid Leukemia iPSCs Reveal a Role for RUNX1 in the Maintenance of Human Leukemia Stem Cells Cell Rep, 2020-06-02;31(9):107688. 2020-06-02 [PMID: 32492433] (Cell Culture, Human) |
Cell Culture |
Human |
| M Meinders, D Shoemark, JGG Dobbe, GJ Streekstra, J Frayne, AM Toye Expression and Retention of Thymidine Phosphorylase in Cultured Reticulocytes as a Novel Treatment for MNGIE Mol Ther Methods Clin Dev, 2020-04-01;17(0):822-830. 2020-04-01 [PMID: 32368563] (Cell Culture, Human) |
Cell Culture |
Human |
| MAE Rab, BA van Oirsch, PA Kosinski, J Hixon, K Johnson, V Chubukov, L Dang, G Pasterkamp, S van Straat, WW van Soling, EJ van Beers, C Kung, R van Wijk AG-348 (Mitapivat), an allosteric activator of red blood cell pyruvate kinase, increases enzymatic activity, protein stability, and ATP levels over a broad range of PKLR genotypes Haematologica, 2021-01-01;0(0):. 2021-01-01 [PMID: 31974203] (Cell Culture, Human) |
Cell Culture |
Human |
| CD Lemke-Milt, SE Blackwell, C Yin, AE Krug, AJ Morris, AM Krieg, GJ Weiner Antibody Opsonization of a TLR9 Agonist-Containing Virus-like Particle Enhances In Situ Immunization J. Immunol., 2020-01-17;204(5):1386-1394. 2020-01-17 [PMID: 31953355] (Bioassay, Human) |
Bioassay |
Human |
| R Leylek, M Alcántara-, Z Lanzar, A Lüdtke, OA Perez, B Reizis, J Idoyaga Integrated Cross-Species Analysis Identifies a Conserved Transitional Dendritic Cell Population Cell Rep, 2019-12-10;29(11):3736-3750.e8. 2019-12-10 [PMID: 31825848] (Cell Culture, Human) |
Cell Culture |
Human |
| VA Balaji Rag, M Anwar, MZ Akhter, A Chavez, Y Mao, V Natarajan, S Lakshmikan, M Chrzanowsk, AZ Dudek, L Claesson-W, JK Kitajewski, KK Wary, AB Malik, D Mehta Sphingosine-1-Phosphate Receptor 1 Activity Promotes Tumor Growth by Amplifying VEGF-VEGFR2 Angiogenic Signaling Cell Rep, 2019-12-10;29(11):3472-3487.e4. 2019-12-10 [PMID: 31825830] (Human) |
|
Human |
| AT Stefka, D Johnson, S Rosebeck, JH Park, Y Nakamura, AJ Jakubowiak Potent anti-myeloma activity of the TOPK inhibitor OTS514 in pre-clinical models Cancer Med, 2019-11-12;0(0):. 2019-11-12 [PMID: 31714026] (Cell Culture, Human) |
Cell Culture |
Human |
| JP Ruiz, G Chen, JJ Haro Mora, K Keyvanfar, C Liu, J Zou, J Beers, H Bloomer, H Qanash, N Uchida, JF Tisdale, M Boehm, A Larochelle Robust generation of erythroid and multilineage hematopoietic progenitors from human iPSCs using a scalable monolayer culture system Stem Cell Res, 2019-10-15;41(0):101600. 2019-10-15 [PMID: 31710911] (Cell Culture, Mouse) |
Cell Culture |
Mouse |
| J Grajcarek, J Monlong, Y Nishinaka-, M Nakamura, M Nagai, S Matsuo, D Lougheed, H Sakurai, MK Saito, G Bourque, K Woltjen Genome-wide microhomologies enable precise template-free editing of biologically relevant deletion mutations Nat Commun, 2019-10-24;10(1):4856. 2019-10-24 [PMID: 31649251] (Bioassay, Human) |
Bioassay |
Human |
| WR Proto, SV Siegel, S Dankwa, W Liu, A Kemp, S Marsden, ZA Zenonos, S Unwin, PM Sharp, GJ Wright, BH Hahn, MT Duraisingh, JC Rayner Adaptation of Plasmodium falciparum to humans involved the loss of an ape-specific erythrocyte invasion ligand Nat Commun, 2019-10-04;10(1):4512. 2019-10-04 [PMID: 31586047] (Cell Culture, Human) |
Cell Culture |
Human |
| N Uchida, MM Hsieh, L Raines, JJ Haro-Mora, S Demirci, AC Bonifacino, AE Krouse, ME Metzger, RE Donahue, JF Tisdale Development of a forward-oriented therapeutic lentiviral vector for hemoglobin disorders Nat Commun, 2019-10-02;10(1):4479. 2019-10-02 [PMID: 31578323] (Cell Culture, Human) |
Cell Culture |
Human |
| M Ly, S Rentas, A Vujovic, N Wong, S Moreira, J Xu, N Holzapfel, S Bhatia, D Tran, MD Minden, JS Draper, KJ Hope Diminished AHR signaling drives human acute myeloid leukemia stem cell maintenance Cancer Res., 2019-09-13;0(0):. 2019-09-13 [PMID: 31519687] (Bioassay, Human) |
Bioassay |
Human |
| MD McKenzie, M Ghisi, EP Oxley, S Ngo, L Cimmino, C Esnault, R Liu, JM Salmon, CC Bell, N Ahmed, M Erlichster, MT Witkowski, GJ Liu, M Chopin, A Dakic, E Simankowic, G Pomilio, T Vu, P Krsmanovic, S Su, L Tian, TM Baldwin, DA Zalcenstei, L DiRago, S Wang, D Metcalf, RW Johnstone, BA Croker, GI Lancaster, AJ Murphy, SH Naik, SL Nutt, V Pospisil, T Schroeder, M Wall, MA Dawson, AH Wei, H de Thé, ME Ritchie, J Zuber, RA Dickins Interconversion between Tumorigenic and Differentiated States in Acute Myeloid Leukemia Cell Stem Cell, 2019-08-01;25(2):258-272.e9. 2019-08-01 [PMID: 31374198] (Cell Culture, Human) |
Cell Culture |
Human |
| M Nasri, M Ritter, P Mir, B Dannenmann, N Aghaallaei, D Amend, V Makaryan, Y Xu, B Fletcher, R Bernhard, I Steiert, K Hahnel, J Berger, I Koch, B Sailer, K Hipp, C Zeidler, M Klimiankou, B Bajoghli, DC Dale, K Welte, J Skokowa CRISPR/Cas9 mediated ELANE knockout enables neutrophilic maturation of primary hematopoietic stem and progenitor cells and induced pluripotent stem cells of severe congenital neutropenia patients Haematologica, 2019-06-27;0(0):. 2019-06-27 [PMID: 31248972] (Bioassay, Human) |
Bioassay |
Human |
| YL Chang, Z Wang, S Igawa, JE Choi, T Werbel, A Di Nardo Lipocalin 2: A New Antimicrobial in Mast Cells Int J Mol Sci, 2019-05-14;20(10):. 2019-05-14 [PMID: 31091692] (Cell Culture, Human) |
Cell Culture |
Human |
| M Ruiz-Gutie, ÖV Bölükba??, G Alexe, AG Kotini, K Ballotti, CE Joyce, DW Russell, K Stegmaier, K Myers, CD Novina, EP Papapetrou, A Shimamura Therapeutic discovery for marrow failure with MDS predisposition using pluripotent stem cells JCI Insight, 2019-04-30;5(0):. 2019-04-30 [PMID: 31039138] (Cell Culture, Human) |
Cell Culture |
Human |
| K Trakarnsan, D Ferguson, DE Daniels, RE Griffiths, MC Wilson, KE Mordue, A Gartner, TN Andrienko, A Calvert, A Condie, A McCahill, JC Mountford, AM Toye, DJ Anstee, J Frayne Vimentin expression is retained in erythroid cells differentiated from human iPSC and ESC and indicates dysregulation in these cells early in differentiation Stem Cell Res Ther, 2019-04-29;10(1):130. 2019-04-29 [PMID: 31036072] (Bioassay, Human) |
Bioassay |
Human |
| B Mair, J Tomic, SN Masud, P Tonge, A Weiss, M Usaj, AHY Tong, JJ Kwan, KR Brown, E Titus, M Atkins, KSK Chan, L Munsie, A Habsid, H Han, M Kennedy, B Cohen, G Keller, J Moffat Essential Gene Profiles for Human Pluripotent Stem Cells Identify Uncharacterized Genes and Substrate Dependencies Cell Rep, 2019-04-09;27(2):599-615.e12. 2019-04-09 [PMID: 30970261] (Differentiation, Differentiation, Human) |
Differentiation, Differentiation |
Human |
| AK Seneviratn, M Xu, JJA Henao, VA Fajardo, Z Hao, V Voisin, GW Xu, R Hurren, S Kim, N MacLean, X Wang, M Gronda, D Jeyaraju, Y Jitkova, T Ketela, M Mullokando, D Sharon, G Thomas, R Chouinard-, JR Hawley, C Schafer, HL Yau, Z Khuchua, A Aman, R Al-Awar, A Gross, SM Claypool, R Bazinet, M Lupien, S Chan, DD De Carvalh, MD Minden, GD Bader, KD Stark, P LeBlanc, AD Schimmer The Mitochondrial Transacylase, Tafazzin, Regulates for AML Stemness by Modulating Intracellular Levels of Phospholipids Cell Stem Cell, 2019-03-28;0(0):. 2019-03-28 [PMID: 30930145] (Bioassay, Human) |
Bioassay |
Human |
| H Xu, B Wang, M Ono, A Kagita, K Fujii, N Sasakawa, T Ueda, P Gee, M Nishikawa, M Nomura, F Kitaoka, T Takahashi, K Okita, Y Yoshida, S Kaneko, A Hotta Targeted Disruption of HLA Genes via CRISPR-Cas9 Generates iPSCs with Enhanced Immune Compatibility Cell Stem Cell, 2019-03-07;0(0):. 2019-03-07 [PMID: 30853558] (Bioassay, Human) |
Bioassay |
Human |
| M Suga, T Kondo, K Imamura, R Shibukawa, Y Okanishi, Y Sagara, K Tsukita, T Enami, M Furujo, K Saijo, Y Nakamura, M Osawa, MK Saito, S Yamanaka, H Inoue Generation of a human induced pluripotent stem cell line, BRCi001-A, derived from a patient with mucopolysaccharidosis type I Stem Cell Res, 2019-02-12;36(0):101406. 2019-02-12 [PMID: 30849633] (Bioassay, Human) |
Bioassay |
Human |
| SL Taylor, J Hogwood, W Guo, EA Yates, JE Turnbull By-Products of Heparin Production Provide a Diverse Source of Heparin-like and Heparan Sulfate Glycosaminoglycans Sci Rep, 2019-02-25;9(1):2679. 2019-02-25 [PMID: 30804383] (Bioassay, Mouse) |
Bioassay |
Mouse |
| S Vangeti, J Gertow, M Yu, S Liu, F Baharom, S Scholz, D Friberg, M Starkhamma, A Ahlberg, A Smed-Sören Human Blood and Tonsil Plasmacytoid Dendritic Cells Display Similar Gene Expression Profiles but Exhibit Differential Type I IFN Responses to Influenza A Virus Infection J. Immunol., 2019-02-13;0(0):. 2019-02-13 [PMID: 30760619] (Bioassay, Human) |
Bioassay |
Human |
| P Potirat, M Wattanapan, V Viprakasit, P Kheolamai, S Issaragris An integration-free iPSC line (MUSIi008-A) derived from a patient with severe hemolytic anemia carrying compound heterozygote mutations in KLF1 gene for disease modeling Stem Cell Res, 2018-12-14;34(0):101344. 2018-12-14 [PMID: 30605837] (Bioassay, Human) |
Bioassay |
Human |
| S Poldee, C Metheetrai, S Nugoolsuks, J Frayne, K Trakarnsan Optimization of an erythroid culture system to reduce the cost of in vitro production of red blood cells MethodsX, 2018-11-30;5(0):1626-1632. 2018-11-30 [PMID: 30560064] (Bioassay, Human) |
Bioassay |
Human |
| AC Glembotsky, D Sliwa, D Bluteau, N Balayn, CP Marin Oyar, A Raimbault, M Bordas, N Droin, I Pirozhkova, V Washington, NP Goette, RF Marta, R Favier, H Raslova, PG Heller Downregulation of TREM-like transcript-1 and collagen receptor ?2 subunit, two novel RUNX1-targets, contributes to platelet dysfunction in familial platelet disorder with predisposition to acute myelogenous leukemia Haematologica, 2018-12-13;104(6):1244-1255. 2018-12-13 [PMID: 30545930] (Bioassay, Human) |
Bioassay |
Human |
| A Hyder, S Ehnert, F Fändrich, H Ungefroren Transfection of Peripheral Blood Monocytes with SOX2 Enhances Multipotency, Proliferation, and Redifferentiation into Neohepatocytes and Insulin-Producing Cells Stem Cells Int, 2018-10-04;2018(0):4271875. 2018-10-04 [PMID: 30402109] (Bioassay, Human) |
Bioassay |
Human |
| N Brookhouse, P Zhang, R Caselli, JJ Kim, DA Brafman Generation and characterization of two human induced pluripotent stem cell (hiPSC) lines homozygous for the Apolipoprotein e4 (APOE4) risk variant-Alzheimer's disease (ASUi005-A) and healthy non-demented control (ASUi006-A) Stem Cell Res, 2018-09-21;32(0):145-149. 2018-09-21 [PMID: 30296667] (Bioassay, Human) |
Bioassay |
Human |
| Karina T Barretto, Calvin M Swanson, Christopher L Nguyen, Douglas S Annis, Stephane J Esnault, Deane F Mosher, Mats W Johansson Control of cytokine-driven eosinophil migratory behavior by TGF-beta-induced protein (TGFBI) and periostin. PLoS ONE, 2018-07-26;0(0):1932-6203. 2018-07-26 [PMID: 30048528] (Bioassay, Human) |
Bioassay |
Human |
| Y Heshmati, S Kharazi, G Türköz, D Chang, E Kamali Dol, J Boström, A Krstic, T Boukoura, E Wagner, N Kadri, R Månsson, M Altun, H Qian, J Walfridsso The histone chaperone NAP1L3 is required for haematopoietic stem cell maintenance and differentiation Sci Rep, 2018-07-25;8(1):11202. 2018-07-25 [PMID: 30046127] (Bioassay, Human) |
Bioassay |
Human |
| Park S, Mostoslavsky G Generation of Human Induced Pluripotent Stem Cells Using a Defined, Feeder-Free Reprogramming System. Curr Protoc Stem Cell Biol, 2018-05-04;45(1):e48. 2018-05-04 [PMID: 30040234] (Bioassay, Human) |
Bioassay |
Human |
| J Zhang, Z Xiang, PA Malaviarac, Y Yan, NJ Baltz, PD Emanuel, YL Liu PTEN is indispensable for cells to respond to MAPK inhibitors in myeloid leukemia Cell. Signal., 2018-06-28;50(0):72-79. 2018-06-28 [PMID: 29964149] (Bioassay, Human) |
Bioassay |
Human |
| A Camgoz, M Paszkowski, S Satpathy, M Wermke, MV Hamann, M von Bonin, C Choudhary, S Knapp, F Buchholz STK3 is a therapeutic target for a subset of acute myeloid leukemias Oncotarget, 2018-05-22;9(39):25458-25473. 2018-05-22 [PMID: 29876001] (Bioassay, Human) |
Bioassay |
Human |
| R Berndt, L Hummitzsch, K He beta , M Albrecht, K Zitta, R Rusch, B Sarras, A Bayer, J Cremer, F Faendrich, J Gro beta Allogeneic transplantation of programmable cells of monocytic origin (PCMO) improves angiogenesis and tissue recovery in critical limb ischemia (CLI): a translational approach Stem Cell Res Ther, 2018-04-27;9(1):117. 2018-04-27 [PMID: 29703251] (Bioassay, Human) |
Bioassay |
Human |
| JM Orengo, AR Radin, V Kamat, A Badithe, LH Ben, BL Bennett, S Zhong, D Birchard, A Limnander, A Rafique, J Bautista, A Kostic, D Newell, X Duan, MC Franklin, W Olson, T Huang, NA Gandhi, L Lipsich, N Stahl, NJ Papadopoul, AJ Murphy, GD Yancopoulo Treating cat allergy with monoclonal IgG antibodies that bind allergen and prevent IgE engagement Nat Commun, 2018-04-12;9(1):1421. 2018-04-12 [PMID: 29650949] (Bioassay, Human) |
Bioassay |
Human |
| M Cesana, MH Guo, D Cacchiarel, L Wahlster, J Barragan, S Doulatov, LT Vo, B Salvatori, C Trapnell, K Clement, P Cahan, KM Tsanov, PM Sousa, B Tazon-Vega, A Bolondi, FM Giorgi, A Califano, JL Rinn, A Meissner, JN Hirschhorn, GQ Daley A CLK3-HMGA2 Alternative Splicing Axis Impacts Human Hematopoietic Stem Cell Molecular Identity throughout Development Cell Stem Cell, 2018-04-05;22(4):575-588.e7. 2018-04-05 [PMID: 29625070] (Bioassay, Human) |
Bioassay |
Human |
| S Kotha, S Sun, A Adams, B Hayes, KT Phong, R Nagao, JA Reems, D Gao, B Torok-Stor, JA López, Y Zheng Microvasculature-directed thrombopoiesis in a 3D in vitro marrow microenvironment PLoS ONE, 2018-04-04;13(4):e0195082. 2018-04-04 [PMID: 29617409] (Bioassay, Human) |
Bioassay |
Human |
| CM Ferrer, M Alders, AV Postma, S Park, MA Klein, M Cetinbas, E Pajkrt, A Glas, S van Koning, VM Christoffe, MMAM Mannens, L Knegt, JP Etchegaray, RI Sadreyev, JM Denu, G Mostoslavs, MC van Maarle, R Mostoslavs An inactivating mutation in the histone deacetylase SIRT6 causes human perinatal lethality Genes Dev., 2018-03-19;32(5):373-388. 2018-03-19 [PMID: 29555651] (Bioassay, Human) |
Bioassay |
Human |
| A Palau, AK Garz, J Diesch, A Zwick, R Malinverni, V Valero, K Lappin, R Casquero, A Lennartsso, J Zuber, T Navarro, KI Mills, KS Götze, M Buschbeck Polycomb protein RING1A limits hematopoietic differentiation in myelodysplastic syndromes Oncotarget, 2017-12-01;8(70):115002-115017. 2017-12-01 [PMID: 29383137] (Bioassay, Human) |
Bioassay |
Human |
| K Schmitt, P Charlins, M Veselinovi, L Kinner-Bib, S Hu, J Curlin, L Remling-Mu, KE Olson, T Aboellail, R Akkina Zika viral infection and neutralizing human antibody response in a BLT humanized mouse model Virology, 2018-01-06;515(0):235-242. 2018-01-06 [PMID: 29310105] (Bioassay, Human) |
Bioassay |
Human |
| M Carretta, AZ Brouwers-V, M Bosman, SJ Horton, JHA Martens, E Vellenga, JJ Schuringa BRD3/4 inhibition and FLT3-ligand deprivation target pathways that are essential for the survival of human MLL-AF9+ leukemic cells PLoS ONE, 2017-12-14;12(12):e0189102. 2017-12-14 [PMID: 29240787] (Bioassay, Human) |
Bioassay |
Human |
| RHP Wilbers, DR van Raaij, LB Westerhof, J Bakker, G Smant, A Schots Re-evaluation of IL-10 signaling reveals novel insights on the contribution of the intracellular domain of the IL-10R2 chain PLoS ONE, 2017-10-10;12(10):e0186317. 2017-10-10 [PMID: 29016674] (Bioassay, Mouse) |
Bioassay |
Mouse |
| S Radecke, K Schwarz, F Radecke Genome-wide Mapping of Off-Target Events in Single-Stranded Oligodeoxynucleotide-Mediated Gene Repair Experiments Mol. Ther., 2017-09-15;26(1):115-131. 2017-09-15 [PMID: 28988714] (Bioassay, Human) |
Bioassay |
Human |
| NJ Palpant, Y Wang, B Hadland, RJ Zaunbreche, M Redd, D Jones, L Pabon, R Jain, J Epstein, WL Ruzzo, Y Zheng, I Bernstein, A Margolin, CE Murry Chromatin and Transcriptional Analysis of Mesoderm Progenitor Cells Identifies HOPX as a Regulator of Primitive Hematopoiesis Cell Rep, 2017-08-15;20(7):1597-1608. 2017-08-15 [PMID: 28813672] (Bioassay, Human) |
Bioassay |
Human |
| L Butcher, M Ahluwalia, T Örd, J Johnston, RH Morris, E Kiss-Toth, T Örd, JD Erusalimsk Evidence for a role of TRIB3 in the regulation of megakaryocytopoiesis Sci Rep, 2017-07-27;7(1):6684. 2017-07-27 [PMID: 28751721] (Bioassay, Human) |
Bioassay |
Human |
| E Varga, C Nemes, I Bock, Z Táncos, S Berzsenyi, G Lévay, V Román, J Kobolák, A Dinnyés Establishment of an induced pluripotent stem cell (iPSC) line from a 9-year old male with autism spectrum disorder (ASD) Stem Cell Res, 2017-03-18;21(0):19-22. 2017-03-18 [PMID: 28677532] (Bioassay, Human) |
Bioassay |
Human |
| H Zhao, S Gulesseria, SK Ganesan, J Ou, K Morrison, Z Zeng, V Robles, J Snyder, L Do, H Aviña, S Karki, DR Stover, F Doñate Inhibition of Megakaryocyte Differentiation by Antibody-Drug Conjugates (ADCs) is Mediated by Macropinocytosis: Implications for ADC Induced Thrombocytopenia Mol. Cancer Ther., 2017-06-27;0(0):. 2017-06-27 [PMID: 28655784] (Bioassay, Human) |
Bioassay |
Human |
| J Huang, A Khan, BC Au, DL Barber, L López-Vásq, NL Prokopishy, M Boutin, M Rothe, JW Rip, M Abaoui, MS Nagree, S Dworski, A Schambach, A Keating, ML West, J Klassen, PV Turner, S Sirrs, CA Rupar, C Auray-Blai, R Foley, JA Medin Lentivector Iterations and Pre-Clinical Scale-Up/Toxicity Testing: Targeting Mobilized CD34(+) Cells for Correction of Fabry Disease Mol Ther Methods Clin Dev, 2017-05-12;5(0):241-258. 2017-05-12 [PMID: 28603745] (Bioassay, Human) |
Bioassay |
Human |
| N Rahman, PM Brauer, L Ho, T Usenko, M Tewary, JC Zúñiga-Pfl, PW Zandstra Engineering the haemogenic niche mitigates endogenous inhibitory signals and controls pluripotent stem cell-derived blood emergence Nat Commun, 2017-05-25;8(0):15380. 2017-05-25 [PMID: 28541275] (Bioassay, Human) |
Bioassay |
Human |
| H Zhao, S Gulesseria, MC Malinao, S Kumar-Gane, J Song, MS Chang, MM Williams, Z Zeng, M Mattie, BA Mendelsohn, DR Stover, F Doñate A Potential Mechanism for ADC-Induced Neutropenia: Role of Neutrophils in Their Own Demise Mol. Cancer Ther., 2017-05-18;0(0):. 2017-05-18 [PMID: 28522588] (Bioassay, Human) |
Bioassay |
Human |
| PA Frischmeye, M Masilamani, W Gu, E Brittain, R Wood, J Kim, K Nadeau, KM Jarvinen, A Grishin, R Lindblad, HA Sampson Mechanistic Correlates of Clinical Responses to Omalizumab in the Setting of Oral Immunotherapy for Milk Allergy J. Allergy Clin. Immunol., 2017-04-13;0(0):. 2017-04-13 [PMID: 28414061] (Bioassay, Human) |
Bioassay |
Human |
| JH Lee, S Laronde, TJ Collins, Z Shapovalov, B Tanasijevi, JD McNicol, A Fiebig-Com, YD Benoit, JB Lee, RR Mitchell, M Bhatia Lineage-Specific Differentiation Is Influenced by State of Human Pluripotency Cell Rep, 2017-04-04;19(1):20-35. 2017-04-04 [PMID: 28380358] (Bioassay, Human) |
Bioassay |
Human |
| DC Thomas, S Clare, JM Sowerby, M Pardo, JK Juss, DA Goulding, L van der We, D Storistean, A Prakash, M Espéli, S Flint, JC Lee, K Hoenderdos, L Kane, K Harcourt, S Mukhopadhy, Y Umrania, R Antrobus, JA Nathan, DJ Adams, A Bateman, JS Choudhary, PA Lyons, AM Condliffe, ER Chilvers, G Dougan, KG Smith Eros is a novel transmembrane protein that controls the phagocyte respiratory burst and is essential for innate immunity J. Exp. Med, 2017-03-28;0(0):. 2017-03-28 [PMID: 28351984] (Bioassay, Human) |
Bioassay |
Human |
| K Trakarnsan, RE Griffiths, MC Wilson, A Blair, TJ Satchwell, M Meinders, N Cogan, S Kupzig, R Kurita, Y Nakamura, AM Toye, DJ Anstee, J Frayne An immortalized adult human erythroid line facilitates sustainable and scalable generation of functional red cells Nat Commun, 2017-03-14;8(0):14750. 2017-03-14 [PMID: 28290447] (Bioassay, Human) |
Bioassay |
Human |
| E Schuh, A Musumeci, FS Thaler, S Laurent, JW Ellwart, R Hohlfeld, A Krug, E Meinl Human Plasmacytoid Dendritic Cells Display and Shed B Cell Maturation Antigen upon TLR Engagement J. Immunol, 2017-03-10;0(0):. 2017-03-10 [PMID: 28283566] (Bioassay, Human) |
Bioassay |
Human |
| SU Liyanage, R Hurren, V Voisin, G Bridon, X Wang, C Xu, N MacLean, TP Siriwarden, M Gronda, D Yehudai, S Sriskantha, D Avizonis, A Shamas-Din, MD Minden, GD Bader, R Laposa, AD Schimmer Leveraging increased cytoplasmic nucleoside kinase activity to target mtDNA and oxidative phosphorylation in AML Blood, 2017-03-10;0(0):. 2017-03-10 [PMID: 28283480] (Bioassay, Human) |
Bioassay |
Human |
| JA Schwartz, KL Clayton, S Mujib, H Zhang, AK Rahman, J Liu, FY Yue, E Benko, C Kovacs, MA Ostrowski Tim-3 is a Marker of Plasmacytoid Dendritic Cell Dysfunction during HIV Infection and Is Associated with the Recruitment of IRF7 and p85 into Lysosomes and with the Submembrane Displacement of TLR9 J. Immunol, 2017-03-06;0(0):. 2017-03-06 [PMID: 28264968] (Bioassay, Human) |
Bioassay |
Human |
| CY Chiu, SC Su, WL Fan, SH Lai, MH Tsai, SH Chen, KS Wong, WH Chung Whole-Genome Sequencing of a Family with Hereditary Pulmonary Alveolar Proteinosis Identifies a Rare Structural Variant Involving CSF2RA/CRLF2/IL3RA Gene Disruption Sci Rep, 2017-02-24;7(0):43469. 2017-02-24 [PMID: 28233860] (Bioassay, Human) |
Bioassay |
Human |
| AG Kotini, CJ Chang, A Chow, H Yuan, TC Ho, T Wang, S Vora, A Solovyov, C Husser, M Olszewska, J Teruya-Fel, D Perumal, VM Klimek, A Spyridonid, RK Rampal, L Silverman, EP Reddy, E Papaemmanu, S Parekh, BD Greenbaum, CS Leslie, MG Kharas, EP Papapetrou Stage-Specific Human Induced Pluripotent Stem Cells Map the Progression of Myeloid Transformation to Transplantable Leukemia Cell Stem Cell, 2017-02-16;0(0):. 2017-02-16 [PMID: 28215825] (Bioassay, Human) |
Bioassay |
Human |
| Ivan Carcamo-Or Analysis of Transcriptional Variability in a Large Human iPSC Library Reveals Genetic and Non-genetic Determinants of Heterogeneity Cell Stem Cell, 2016-12-22;0(0):. 2016-12-22 [PMID: 28017796] (Bioassay, Human) |
Bioassay |
Human |
| Ras oncogene-independent activation of RALB signaling is a targetable mechanism of escape from NRAS(V12) oncogene addiction in acute myeloid leukemia Oncogene, 2016-12-19;0(0):. 2016-12-19 [PMID: 27991934] (Bioassay, Human) |
Bioassay |
Human |
| Preclinical validation: LV/IL-12 transduction of patient leukemia cells for immunotherapy of AML Mol Ther Methods Clin Dev, 2016-12-07;3(0):16074. 2016-12-07 [PMID: 27933304] (Bioassay, Human) |
Bioassay |
Human |
| Amber N Stratman Mural-Endothelial cell-cell interactions stabilize the developing zebrafish dorsal aorta Development, 2016-12-02;0(0):. 2016-12-02 [PMID: 27913637] (Bioassay, Human) |
Bioassay |
Human |
| Leucine-Rich Repeat Kinase 2 Influences Fate Decision of Human Monocytes Differentiated from Induced Pluripotent Stem Cells PLoS ONE, 2016-11-03;11(11):e0165949. 2016-11-03 [PMID: 27812199] (Bioassay, Human) |
Bioassay |
Human |
| Improved hematopoietic differentiation of human pluripotent stem cells via estrogen receptor signaling pathway Cell Biosci, 2016-08-30;6(1):50. 2016-08-30 [PMID: 27583127] (Bioassay, Human) |
Bioassay |
Human |
| Polyurethane scaffolds seeded with CD34(+) cells maintain early stem cells whilst also facilitating prolonged egress of haematopoietic progenitors Sci Rep, 2016-08-30;6(0):32149. 2016-08-30 [PMID: 27573994] (Bioassay, Human) |
Bioassay |
Human |
| Functional IL-33 receptors are expressed in early progenitor stages of allergy-related granulocytes Immunology, 2016-09-30;0(0):. 2016-09-30 [PMID: 27568595] (Bioassay, Human) |
Bioassay |
Human |
| A New Glucocerebrosidase Chaperone Reduces ?-Synuclein and Glycolipid Levels in iPSC-Derived Dopaminergic Neurons from Patients with Gaucher Disease and Parkinsonism J Neurosci, 2016-07-13;36(28):7441-52. 2016-07-13 [PMID: 27413154] (Bioassay, Human) |
Bioassay |
Human |
| Decitabine enhances anti-CD33 monoclonal antibody BI 836858-mediated natural killer ADCC against AML blasts Blood, 2016-03-24;127(23):2879-89. 2016-03-24 [PMID: 27013443] (Bioassay, Human) |
Bioassay |
Human |
| Isabela Pedroza-Pa, Divya Shah, Anna Domogala, Martha Luevano, Michael Blundell, Nicola Jackson, Adrian Thrasher, Alejandro Madrigal, Aurore Saudemont Regulatory T cells inhibit CD34+ cell differentiation into NK cells by blocking their proliferation. Scientific Reports, 2016-02-26;0(0):2045-2322. 2016-02-26 [PMID: 26915707] (In Vivo, Xenograft) |
In Vivo |
Xenograft |
| Park I, Mundy-Bosse B, Whitman S, Zhang X, Warner S, Bearss D, Blum W, Marcucci G, Caligiuri M Receptor tyrosine kinase Axl is required for resistance of leukemic cells to FLT3-targeted therapy in acute myeloid leukemia. Leukemia, 2015-06-19;29(12):2382-9. 2015-06-19 [PMID: 26172401] (Bioassay, Human) |
Bioassay |
Human |
| Shima T, Iwasaki H, Yamauchi T, Kadowaki M, Kiyosuke M, Mochimaru T, Takenaka K, Miyamoto T, Akashi K, Teshima T Preserved in vivo reconstitution ability of PBSCs cryopreserved for a decade at -80 degrees C. Bone Marrow Transplant, 2015-06-22;50(9):1195-200. 2015-06-22 [PMID: 26098951] (Bioassay, Human) |
Bioassay |
Human |
| Jiang X, Lim C, Li Z, Lee P, Yatim S, Guan P, Li J, Zhou J, Pan J, Chng W, Chai C, Yu Q Functional Characterization of D9, a Novel Deazaneplanocin A (DZNep) Analog, in Targeting Acute Myeloid Leukemia (AML). PLoS ONE, 2015-04-30;10(4):e0122983. 2015-04-30 [PMID: 25928216] (Bioassay, Human) |
Bioassay |
Human |
| Sterba P, Hamilton R, Saini S Suppression of basophil FcvarepsilonRI activation by serum from active chronic idiopathic/spontaneous urticaria (CIU/CSU) subjects. J Invest Dermatol, 2015-02-03;135(5):1454-6. 2015-02-03 [PMID: 25885681] (Bioassay, Human) |
Bioassay |
Human |
| Patterson , Scott D, Rossi , John M, Paweletz , Katherin, Fitzpatrick , V Dan, Begley , C Glenn, Busse , Leigh, Elliott , Steve, McCaffery , Ian Functional EpoR pathway utilization is not detected in primary tumor cells isolated from human breast, non-small cell lung, colorectal, and ovarian tumor tissues. PLoS ONE, 2015-03-25;10(3):e0122149. 2015-03-25 [PMID: 25807104] (Bioassay, Human) |
Bioassay |
Human |
| Baharom F, Thomas S, Bieder A, Hellmer M, Volz J, Sandgren K, McInerney G, Karlsson Hedestam G, Mellman I, Smed-Sorensen A Protection of human myeloid dendritic cell subsets against influenza A virus infection is differentially regulated upon TLR stimulation. J Immunol, 2015-03-23;194(9):4422-30. 2015-03-23 [PMID: 25801434] (Bioassay, Human) |
Bioassay |
Human |
| Dyer , Kimberly, Rosenberg , Helene F Physiologic concentrations of HMGB1 have no impact on cytokine-mediated eosinophil survival or chemotaxis in response to Eotaxin-2 (CCL24). PLoS ONE, 2015-03-16;10(3):e0118887. 2015-03-16 [PMID: 25774667] (Bioassay, Human) |
Bioassay |
Human |
| Ungefroren H, Hyder A, Hinz H, Groth S, Lange H, El-Sayed K, Ehnert S, Nussler A, Fandrich F, Gieseler F Pluripotency gene expression and growth control in cultures of peripheral blood monocytes during their conversion into programmable cells of monocytic origin (PCMO): evidence for a regulatory role of autocrine activin and TGF-beta. PLoS ONE, 2015-02-23;10(2):e0118097. 2015-02-23 [PMID: 25707005] (Bioassay, Human) |
Bioassay |
Human |
| Lee J, Graham M, Collins T, Lee J, Hong S, McNicol A, Shapovalova Z, Bhatia M Reversible lineage-specific priming of human embryonic stem cells can be exploited to optimize the yield of differentiated cells. Stem Cells, 2015-04-01;33(4):1142-52. 2015-04-01 [PMID: 25639500] (Bioassay, Human) |
Bioassay |
Human |
| Scheuplein V, Seifried J, Malczyk A, Miller L, Hocker L, Vergara-Alert J, Dolnik O, Zielecki F, Becker B, Spreitzer I, Konig R, Becker S, Waibler Z, Muhlebach M High secretion of interferons by human plasmacytoid dendritic cells upon recognition of Middle East respiratory syndrome coronavirus. J Virol, 2015-01-21;89(7):3859-69. 2015-01-21 [PMID: 25609809] (Bioassay, Human) |
Bioassay |
Human |
| Baldwin K, Urbinati F, Romero Z, Campo-Fernandez B, Kaufman M, Cooper A, Masiuk K, Hollis R, Kohn D Enrichment of human hematopoietic stem/progenitor cells facilitates transduction for stem cell gene therapy. Stem Cells, 2015-05-01;33(5):1532-42. 2015-05-01 [PMID: 25588820] (Bioassay, Human) |
Bioassay |
Human |
| Purushothaman P, Thakker S, Verma S Transcriptome analysis of Kaposi's sarcoma-associated herpesvirus during de novo primary infection of human B and endothelial cells. J Virol, 2014-12-31;89(6):3093-111. 2014-12-31 [PMID: 25552714] (Bioassay, Human) |
Bioassay |
Human |
| Matsuoka Y, Nakatsuka R, Sumide K, Kawamura H, Takahashi M, Fujioka T, Uemura Y, Asano H, Sasaki Y, Inoue M, Ogawa H, Takahashi T, Hino M, Sonoda Y Prospectively Isolated Human Bone Marrow Cell-Derived MSCs Support Primitive Human CD34-Negative Hematopoietic Stem Cells. Stem Cells, 2015-05-01;33(5):1554-65. 2015-05-01 [PMID: 25537923] (Bioassay, Human) |
Bioassay |
Human |
| Gallagher K, Joshi A, Carson W, Schaller M, Allen R, Mukerjee S, Kittan N, Feldman E, Henke P, Hogaboam C, Burant C, Kunkel S Epigenetic changes in bone marrow progenitor cells influence the inflammatory phenotype and alter wound healing in type 2 diabetes. Diabetes, 2014-11-03;64(4):1420-30. 2014-11-03 [PMID: 25368099] (Bioassay, Human) |
Bioassay |
Human |
| Li B, Baylink D, Walter M, Lau K, Meng X, Wang J, Cherkas A, Tang X, Qin X Targeted 25-hydroxyvitamin D3 1alpha-hydroxylase adoptive gene therapy ameliorates dss-induced colitis without causing hypercalcemia in mice. Mol Ther, 2014-10-20;23(2):339-51. 2014-10-20 [PMID: 25327179] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Lederle A, Su B, Holl V, Penichon J, Schmidt S, Decoville T, Laumond G, Moog C Neutralizing antibodies inhibit HIV-1 infection of plasmacytoid dendritic cells by an FcgammaRIIa independent mechanism and do not diminish cytokines production. Sci Rep, 2014-08-18;4(0):5845. 2014-08-18 [PMID: 25132382] (Bioassay, Human) |
Bioassay |
Human |
| Xia C, Peng R, Chernatynskaya A, Yuan L, Carter C, Valentine J, Sobel E, Atkinson M, Clare-Salzler M Increased IFN-alpha-producing plasmacytoid dendritic cells (pDCs) in human Th1-mediated type 1 diabetes: pDCs augment Th1 responses through IFN-alpha production. J Immunol, 2014-06-27;193(3):1024-34. 2014-06-27 [PMID: 24973447] (Bioassay, Human) |
Bioassay |
Human |
| Lin A, Burrascano C, Pettersson P, Ibanez C, Gruber H, Jolly D Blockade of type I interferon (IFN) production by retroviral replicating vectors and reduced tumor cell responses to IFN likely contribute to tumor selectivity. J Virol, 2014-06-25;88(17):10066-77. 2014-06-25 [PMID: 24965455] (Bioassay, Human) |
Bioassay |
Human |
| Smith , Laura J, Ul-Hasan , Taihra, Carvaines , Sarah K, Van Vliet , Kim, Yang , Ethel, Wong , Kamehame, Agbandje-McKenna , Mavis, Chatterjee , Saswati Gene transfer properties and structural modeling of human stem cell-derived AAV. Mol Ther, 2014-06-13;22(9):1625-34. 2014-06-13 [PMID: 24925207] (Bioassay, Human) |
Bioassay |
Human |
| Jitkova , Yulia, Gronda , Marcela, Hurren , Rose, Wang , Xiaoming, Goard , Carolyn, Jhas , Bozhena, Schimmer , Aaron D A novel formulation of tigecycline has enhanced stability and sustained antibacterial and antileukemic activity. PLoS ONE, 2014-05-28;9(5):e95281. 2014-05-28 [PMID: 24871339] (Bioassay, Human) |
Bioassay |
Human |
| Yang C, French A, Goh P, Pagnamenta A, Mettananda S, Taylor J, Knight S, Nathwani A, Roberts D, Watt S, Carpenter L Human induced pluripotent stem cell derived erythroblasts can undergo definitive erythropoiesis and co-express gamma and beta globins. Br J Haematol, 2014-05-16;166(3):435-48. 2014-05-16 [PMID: 24837254] (Bioassay, Human) |
Bioassay |
Human |
| Morshed M, Hlushchuk R, Simon D, Walls A, Obata-Ninomiya K, Karasuyama H, Djonov V, Eggel A, Kaufmann T, Simon H, Yousefi S NADPH oxidase-independent formation of extracellular DNA traps by basophils. J Immunol, 2014-04-25;192(11):5314-23. 2014-04-25 [PMID: 24771850] (Bioassay, Human) |
Bioassay |
Human |
| Chaurasia P, Gajzer D, Schaniel C, D'Souza S, Hoffman R Epigenetic reprogramming induces the expansion of cord blood stem cells. J Clin Invest, 2014-04-24;124(6):2378-95. 2014-04-24 [PMID: 24762436] (Bioassay, Human) |
Bioassay |
Human |
| Drewes J, Szeto G, Engle E, Liao Z, Shearer G, Zink M, Graham D Attenuation of pathogenic immune responses during infection with human and simian immunodeficiency virus (HIV/SIV) by the tetracycline derivative minocycline. PLoS ONE, 2014-04-14;9(4):e94375. 2014-04-14 [PMID: 24732038] (Bioassay, Human) |
Bioassay |
Human |
| Williams M, Yousafzai Y, Cox C, Blair A, Carmody R, Sai S, Chapman K, McAndrew R, Thomas A, Spence A, Gibson B, Graham G, Halsey C Interleukin-15 enhances cellular proliferation and upregulates CNS homing molecules in pre-B acute lymphoblastic leukemia. Blood, 2014-04-03;123(20):3116-27. 2014-04-03 [PMID: 24700781] (Bioassay, Human) |
Bioassay |
Human |
| Li X, Romain R, Park D, Scadden D, Merchant J, Arnaout M Stress hematopoiesis is regulated by the Kruppel-like transcription factor ZBP-89. Stem Cells, 2014-03-01;32(3):791-801. 2014-03-01 [PMID: 24549639] (Bioassay, Human) |
Bioassay |
Human |
| Jensen B, Frandsen P, Raaby E, Schiotz P, Skov P, Poulsen L Molecular and stimulus-response profiles illustrate heterogeneity between peripheral and cord blood-derived human mast cells. J Leukoc Biol, 2014-02-03;95(6):893-901. 2014-02-03 [PMID: 24493825] (Bioassay, Human) |
Bioassay |
Human |
| van Wilgenburg , Bonnie, Moore , Michael, James , William, Cowley , Sally A The productive entry pathway of HIV-1 in macrophages is dependent on endocytosis through lipid rafts containing CD4. PLoS ONE, 2014-01-22;9(1):e86071. 2014-01-22 [PMID: 24465876] (Bioassay, Human) |
Bioassay |
Human |
| Kamat V, Paluru P, Myint M, French D, Gadue P, Diamond S MicroRNA screen of human embryonic stem cell differentiation reveals miR-105 as an enhancer of megakaryopoiesis from adult CD34+ cells. Stem Cells, 2014-05-01;32(5):1337-46. 2014-05-01 [PMID: 24446170] (Bioassay, Human) |
Bioassay |
Human |
| Smith A, Bowers S, Stratman A, Davis G Hematopoietic stem cell cytokines and fibroblast growth factor-2 stimulate human endothelial cell-pericyte tube co-assembly in 3D fibrin matrices under serum-free defined conditions. PLoS ONE, 2013-12-31;8(12):e85147. 2013-12-31 [PMID: 24391990] (Bioassay, Human) |
Bioassay |
Human |
| Klimenkova O, Ellerbeck W, Klimiankou M, Unalan M, Kandabarau S, Gigina A, Hussein K, Zeidler C, Welte K, Skokowa J A lack of secretory leukocyte protease inhibitor (SLPI) causes defects in granulocytic differentiation. Blood, 2013-12-18;123(8):1239-49. 2013-12-18 [PMID: 24352879] (Bioassay, Human) |
Bioassay |
Human |
| Voskamp A, Prickett S, Mackay F, Rolland J, O'Hehir R MHC class II expression in human basophils: induction and lack of functional significance. PLoS ONE, 2013-12-09;8(12):e81777. 2013-12-09 [PMID: 24349126] (Cell Culture, Human) |
Cell Culture |
Human |
| Thanunchai , Maytawan, Kanrai , Pumaree, Wiboon-Ut , Suwimon, Puthavathana , Pilaipan, Hongeng , Suradej, Thitithanyanont , Arunee Tropism of avian influenza A (H5N1) virus to mesenchymal stem cells and CD34+ hematopoietic stem cells. PLoS ONE, 2013-12-10;8(12):e81805. 2013-12-10 [PMID: 24339969] (Bioassay, Human) |
Bioassay |
Human |
| Tolar J, McGrath J, Xia L, Riddle M, Lees C, Eide C, Keene D, Liu L, Osborn M, Lund T, Blazar B, Wagner J Patient-specific naturally gene-reverted induced pluripotent stem cells in recessive dystrophic epidermolysis bullosa. J Invest Dermatol, 2013-12-06;134(5):1246-54. 2013-12-06 [PMID: 24317394] (Bioassay, Human) |
Bioassay |
Human |
| Jia X, Cong B, Zhang J, Li H, Liu W, Chang H, Dong M, Ma C CCK8 negatively regulates the TLR9-induced activation of human peripheral blood pDCs by targeting TRAF6 signaling. Eur J Immunol, 2013-12-02;44(2):489-99. 2013-12-02 [PMID: 24301797] (Bioassay, Human) |
Bioassay |
Human |
| Liu , Suiyang, Yin , Li, Stroopinsky , Dina, Rajabi , Hasan, Puissant , Alexandr, Stegmaier , Kimberly, Avigan , David, Kharbanda , Surender, Kufe , Donald, Stone , Richard MUC1-C oncoprotein promotes FLT3 receptor activation in acute myeloid leukemia cells. Blood, 2013-11-26;123(5):734-42. 2013-11-26 [PMID: 24282218] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Takahashi , M, Matsuoka , Y, Sumide , K, Nakatsuka , R, Fujioka , T, Kohno , H, Sasaki , Y, Matsui , K, Asano , H, Kaneko , K, Sonoda , Y CD133 is a positive marker for a distinct class of primitive human cord blood-derived CD34-negative hematopoietic stem cells. Leukemia, 2013-11-05;28(6):1308-15. 2013-11-05 [PMID: 24189293] (Bioassay, Human) |
Bioassay |
Human |
| Doulatov S, Vo L, Chou S, Kim P, Arora N, Li H, Hadland B, Bernstein I, Collins J, Zon L, Daley G Induction of multipotential hematopoietic progenitors from human pluripotent stem cells via respecification of lineage-restricted precursors. Cell Stem Cell, 2013-10-03;13(4):459-70. 2013-10-03 [PMID: 24094326] (Bioassay, Human) |
Bioassay |
Human |
| Morishima , Tatsuya, Watanabe , Ken-ichi, Niwa , Akira, Hirai , Hideyo, Saida , Satoshi, Tanaka , Takayuki, Kato , Itaru, Umeda , Katsutsu, Hiramatsu , Hidefumi, Saito , Megumu K, Matsubara , Kousaku, Adachi , Souichi, Kobayashi , Masao, Nakahata , Tatsutos, Heike , Toshio Genetic correction of HAX1 in induced pluripotent stem cells from a patient with severe congenital neutropenia improves defective granulopoiesis. Haematologica, 2013-08-23;99(1):19-27. 2013-08-23 [PMID: 23975175] (Bioassay, Human) |
Bioassay |
Human |
| Einwallner E, Jaeger E, Mitterbauer-Hohendanner G, Bilban M, Simonitsch-Klupp I, Steiner I, Pernicka E, Hoermann G, Herndlhofer S, Sillaber C, Valent P, Schwarzinger I Endogenous erythroid colony formation in chronic myeloid leukemia: a recurrent finding associated with persistent minimal residual disease under imatinib. Stem Cells Dev, 2013-09-04;22(23):3043-51. 2013-09-04 [PMID: 23883175] (Bioassay, Human) |
Bioassay |
Human |
| Rosen L, Freeman A, Yang L, Jutivorakool K, Olivier K, Angkasekwinai N, Suputtamongkol Y, Bennett J, Pyrgos V, Williamson P, Ding L, Holland S, Browne S Anti-GM-CSF autoantibodies in patients with cryptococcal meningitis. J Immunol, 2013-03-18;190(8):3959-66. 2013-03-18 [PMID: 23509356] (Bioassay, Human) |
Bioassay |
Human |
| Yu , Jianhua, Peng , Yong, Wu , Lai-Chu, Xie , Zhiliang, Deng , Youcai, Hughes , Tiffany, He , Shun, Mo , XiaoKui, Chiu , Ming, Wang , Qi-En, He , Xiaoming, Liu , Shujun, Grever , Michael, Chan , Kenneth, Liu , Zhongfa Curcumin down-regulates DNA methyltransferase 1 and plays an anti-leukemic role in acute myeloid leukemia. PLoS ONE, 2013-02-13;8(2):e55934. 2013-02-13 [PMID: 23457487] (Bioassay, Human) |
Bioassay |
Human |
| Giannoni F, Hardee C, Wherley J, Gschweng E, Senadheera S, Kaufman M, Chan R, Bahner I, Gersuk V, Wang X, Gjertson D, Baltimore D, Witte O, Economou J, Ribas A, Kohn D Allelic exclusion and peripheral reconstitution by TCR transgenic T cells arising from transduced human hematopoietic stem/progenitor cells. Mol Ther, 2013-02-05;21(5):1044-54. 2013-02-05 [PMID: 23380815] (Bioassay, Human) |
Bioassay |
Human |
| Alysandratos K, Asadi S, Angelidou A, Zhang B, Sismanopoulos N, Yang H, Critchfield A, Theoharides T Neurotensin and CRH interactions augment human mast cell activation. PLoS ONE, 2012-11-14;7(11):e48934. 2012-11-14 [PMID: 23155429] (Bioassay, Human) |
Bioassay |
Human |
| Targeting of CD34+CD38- cells using Gemtuzumab ozogamicin (Mylotarg) in combination with tipifarnib (Zarnestra) in Acute Myeloid Leukaemia. BMC Cancer, 2012-09-26;12(0):431. 2012-09-26 [PMID: 23013471] (Bioassay, Human) |
Bioassay |
Human |
| Stromal cells expressing hedgehog-interacting protein regulate the proliferation of myeloid neoplasms. Blood Cancer J, 2012-09-07;2(0):e87. 2012-09-07 [PMID: 22961059] (Bioassay, Human) |
Bioassay |
Human |
| Li Q, Ramirez-Bergeron D, Dunwoodie S, Yang Y Cited2 gene controls pluripotency and cardiomyocyte differentiation of murine embryonic stem cells through Oct4 gene. J Biol Chem, 2012-07-03;287(34):29088-100. 2012-07-03 [PMID: 22761414] (Bioassay, Human) |
Bioassay |
Human |
| Donhauser N, Pritschet K, Helm M, Harrer T, Schuster P, Ries M, Bischof G, Vollmer J, Smola S, Schmidt B Chronic immune activation in HIV-1 infection contributes to reduced interferon alpha production via enhanced CD40:CD40 ligand interaction. PLoS ONE, 2012-03-21;7(3):e33925. 2012-03-21 [PMID: 22470494] (Bioassay, Human) |
Bioassay |
Human |
| Torrano V, Procter J, Cardus P ETV6-RUNX1 promotes survival of early B lineage progenitor cells via a dysregulated erythropoietin receptor. Blood, 2011-09-07;118(18):4910-8. 2011-09-07 [PMID: 21900195] (Bioassay, Human) |
Bioassay |
Human |
| Bond E, Liang F, Sandgren KJ, Smed-Sorensen A, Bergman P, Brighenti S, Adams WC, Betemariam SA, Rangaka MX, Lange C, Wilkinson RJ, Andersson J, Lore K Plasmacytoid dendritic cells infiltrate the skin in positive tuberculin skin test indurations. J. Invest. Dermatol., 2011-08-18;132(1):114-23. 2011-08-18 [PMID: 21850028] (Bioassay, Human) |
Bioassay |
Human |
| Niwa A, Heike T, Umeda K A novel serum-free monolayer culture for orderly hematopoietic differentiation of human pluripotent cells via mesodermal progenitors. PLoS ONE, 2011-07-27;6(7):e22261. 2011-07-27 [PMID: 21818303] (Bioassay, Human) |
Bioassay |
Human |
| Uchida N, Hsieh MM, Hayakawa J, Madison C, Washington KN, Tisdale JF Optimal conditions for lentiviral transduction of engrafting human CD34+ cells. Gene Ther., 2011-05-05;18(11):1078-86. 2011-05-05 [PMID: 21544097] (Bioassay, Human) |
Bioassay |
Human |
| Perier A, Fregni G, Wittnebel S, Gad S, Allard M, Gervois N, Escudier B, Azzarone B, Caignard A Mutations of the von Hippel-Lindau gene confer increased susceptibility to natural killer cells of clear-cell renal cell carcinoma. Oncogene, 2011-01-24;30(23):2622-32. 2011-01-24 [PMID: 21258414] (Bioassay, Human) |
Bioassay |
Human |
| Tolar J, Park I, Xia L, Lees C, Peacock B, Webber B, McElmurry R, Eide C, Orchard P, Kyba M, Osborn M, Lund T, Wagner J, Daley G, Blazar B Hematopoietic differentiation of induced pluripotent stem cells from patients with mucopolysaccharidosis type I (Hurler syndrome). Blood, 2010-10-29;117(3):839-47. 2010-10-29 [PMID: 21037085] (Bioassay, Human) |
Bioassay |
Human |
| Kirouac DC, Ito C, Csaszar E, Roch A, Yu M, Sykes EA, Bader GD, Zandstra PW Dynamic interaction networks in a hierarchically organized tissue. Mol. Syst. Biol., 2010-10-05;6(0):417. 2010-10-05 [PMID: 20924352] (Bioassay, Human) |
Bioassay |
Human |
| Gupta N, Barhanpurkar AP, Tomar GB IL-3 inhibits human osteoclastogenesis and bone resorption through downregulation of c-Fms and diverts the cells to dendritic cell lineage. J. Immunol., 2010-07-19;185(4):2261-72. 2010-07-19 [PMID: 20644169] (Bioassay, Human) |
Bioassay |
Human |
| Ghirelli C, Zollinger R, Soumelis V Systematic cytokine receptor profiling reveals GM-CSF as a novel TLR-independent activator of human plasmacytoid predendritic cells. Blood, 2010-04-09;115(24):5037-40. 2010-04-09 [PMID: 20382843] (Bioassay, Human) |
Bioassay |
Human |
| Stratman AN, Malotte KM, Mahan RD, Davis MJ, Davis GE Pericyte recruitment during vasculogenic tube assembly stimulates endothelial basement membrane matrix formation. Blood, 2009-10-12;114(24):5091-101. 2009-10-12 [PMID: 19822899] (Bioassay, Human) |
Bioassay |
Human |
| Ye L, Chang JC, Lin C, Sun X, Yu J, Kan YW Induced pluripotent stem cells offer new approach to therapy in thalassemia and sickle cell anemia and option in prenatal diagnosis in genetic diseases. Proc. Natl. Acad. Sci. U.S.A., 2009-05-29;106(24):9826-30. 2009-05-29 [PMID: 19482945] (Bioassay, Human) |
Bioassay |
Human |
| Cattaruzza L, Gloghini A, Olivo K, Di Francia R, Lorenzon D, De Filippi R, Carbone A, Colombatti A, Pinto A, Aldinucci D Functional coexpression of Interleukin (IL)-7 and its receptor (IL-7R) on Hodgkin and Reed-Sternberg cells: Involvement of IL-7 in tumor cell growth and microenvironmental interactions of Hodgkin's lymphoma. Int. J. Cancer, 2009-09-01;125(5):1092-101. 2009-09-01 [PMID: 19391137] (Bioassay, Human) |
Bioassay |
Human |
| Sorrentino A, Ferracin M, Castelli G, Biffoni M, Tomaselli G, Baiocchi M, Fatica A, Negrini M, Peschle C, Valtieri M Isolation and characterization of CD146+ multipotent mesenchymal stromal cells. Exp. Hematol., 2008-05-27;36(8):1035-46. 2008-05-27 [PMID: 18504067] (Bioassay, Human) |
Bioassay |
Human |
| Fernandez L, Rodriguez S, Huang H, Chora A, Fernandes J, Mumaw C, Cruz E, Pollok K, Cristina F, Price JE, Ferkowicz MJ, Scadden DT, Clauss M, Cardoso AA, Carlesso N Tumor necrosis factor-alpha and endothelial cells modulate Notch signaling in the bone marrow microenvironment during inflammation. Exp. Hematol., 2008-05-01;36(5):545-558. 2008-05-01 [PMID: 18439488] (Bioassay, Human) |
Bioassay |
Human |
| McCullar V, Oostendorp R, Panoskaltsis-Mortari A, Yun G, Lutz CT, Wagner JE, Miller JS Mouse fetal and embryonic liver cells differentiate human umbilical cord blood progenitors into CD56-negative natural killer cell precursors in the absence of interleukin-15. Exp. Hematol., 2008-03-04;36(5):598-608. 2008-03-04 [PMID: 18295962] (Bioassay, Human) |
Bioassay |
Human |
| Rajesh</LastName><ForeNam D</Initial, Rajesh D, Chinnasamy N, Mitalipov SM, Wolf DP, Slukvin I, Thomson JA, Shaaban AF Differential requirements for hematopoietic commitment between human and rhesus embryonic stem cells. Stem Cells, 2007-02-01;25(2):490-9. 2007-02-01 [PMID: 17284653] (Bioassay, Human, Mouse, Primate - Macaca mulatta (Rhesus Macaque)) |
Bioassay |
Human, Mouse, Primate - Macaca mulatta (Rhesus Macaque) |
| Pontikoglou C, Liapakis G, Pyrovolaki K, Papadakis M, Bux J, Eliopoulos GD, Papadaki HA Evidence for downregulation of erythropoietin receptor in bone marrow erythroid cells of patients with chronic idiopathic neutropenia. Exp. Hematol., 2006-10-01;34(10):1312-22. 2006-10-01 [PMID: 16982324] (Bioassay, Human) |
Bioassay |
Human |
| Munitz A, Bachelet I, Eliashar R, Khodoun M, Finkelman FD, Rothenberg ME, Levi-Schaffer F CD48 is an allergen and IL-3-induced activation molecule on eosinophils. J. Immunol., 2006-07-01;177(1):77-83. 2006-07-01 [PMID: 16785501] (Bioassay, Human) |
Bioassay |
Human |
| Vassina EM, Yousefi S, Simon D, Zwicky C, Conus S, Simon HU cIAP-2 and survivin contribute to cytokine-mediated delayed eosinophil apoptosis. Eur. J. Immunol., 2006-07-01;36(7):1975-84. 2006-07-01 [PMID: 16761316] (Bioassay, Human) |
Bioassay |
Human |
| Hiroyama T, Miharada K, Aoki N, Fujioka T, Sudo K, Danjo I, Nagasawa T, Nakamura Y Long-lasting in vitro hematopoiesis derived from primate embryonic stem cells. Exp. Hematol., 2006-06-01;34(6):760-9. 2006-06-01 [PMID: 16728281] (Bioassay, Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque)) |
Bioassay |
Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque) |
| Yokoi H, Myers A, Matsumoto K, Crocker PR, Saito H, Bochner BS Alteration and acquisition of Siglecs during in vitro maturation of CD34+ progenitors into human mast cells. Allergy, 2006-06-01;61(6):769-76. 2006-06-01 [PMID: 16677248] (Bioassay, Human) |
Bioassay |
Human |
| Gemelli C, Montanari M, Tenedini E, Zanocco Marani T, Vignudelli T, Siena M, Zini R, Salati S, Tagliafico E, Manfredini R, Grande A, Ferrari S Virally mediated MafB transduction induces the monocyte commitment of human CD34+ hematopoietic stem/progenitor cells. Cell Death Differ., 2006-02-03;13(10):1686-96. 2006-02-03 [PMID: 16456583] (Bioassay, Human) |
Bioassay |
Human |
| Hanley MB, Napolitano LA, McCune JM Growth hormone-induced stimulation of multilineage human hematopoiesis. Stem Cells, 2005-06-13;23(8):1170-9. 2005-06-13 [PMID: 15955828] (Bioassay, Human) |
Bioassay |
Human |
| Congote LF, DiFalco MR, Gibbs BF Thrombospondin 1, produced by endothelial cells under the action of erythropoietin, stimulates thymidine incorporation into erythroid cells and counteracts the inhibitory action of insulin-like growth factor binding protein 3. Cytokine, 2005-03-23;30(5):248-53. 2005-03-23 [PMID: 15927849] (Bioassay, Human) |
Bioassay |
Human |
| Femenia F, Arock M, Leriche L, Delouis C, Millet G, Ben Hamouda N, Cote M, Alliot A, Lilin T, Pinton A, Iannucceli N, Parodi AL, Boireau P Establishment and characterization of continuous hematopoietic progenitors-derived pig normal mast cell lines. Life Sci., 2005-07-01;77(7):808-23. 2005-07-01 [PMID: 15896811] (Bioassay, Porcine) |
Bioassay |
Porcine |
| Kao CY, Chen Y, Thai P, Wachi S, Huang F, Kim C, Harper RW, Wu R IL-17 markedly up-regulates beta-defensin-2 expression in human airway epithelium via JAK and NF-kappaB signaling pathways. J. Immunol., 2004-09-01;173(5):3482-91. 2004-09-01 [PMID: 15322213] (Bioassay, Human) |
Bioassay |
Human |
| Uchida K, Nakata K, Trapnell BC, Terakawa T, Hamano E, Mikami A, Matsushita I, Seymour JF, Oh-Eda M, Ishige I, Eishi Y, Kitamura T, Yamada Y, Hanaoka K, Keicho N High-affinity autoantibodies specifically eliminate granulocyte-macrophage colony-stimulating factor activity in the lungs of patients with idiopathic pulmonary alveolar proteinosis. Blood, 2003-09-25;103(3):1089-98. 2003-09-25 [PMID: 14512323] (SDS-Page, Human) |
SDS-Page |
Human |
| Bug G, Rossmanith T, Henschler R, Kunz-Schughart LA, Schroder B, Kampfmann M, Kreutz M, Hoelzer D, Ottmann OG Rho family small GTPases control migration of hematopoietic progenitor cells into multicellular spheroids of bone marrow stroma cells. J. Leukoc. Biol., 2002-10-01;72(4):837-45. 2002-10-01 [PMID: 12377954] (Bioassay, Human) |
Bioassay |
Human |
| Manz MG, 107325, Miyamoto T, Akashi K, Weissman IL Prospective isolation of human clonogenic common myeloid progenitors. Ultra-Sensitive and Semi-Quantitative Vertical Flow Assay for the Rapid Detection of Interleukin-6 in Inflammatory Diseases, 2002-08-22;99(18):11872-7. 2002-08-22 [PMID: 12193648] (Bioassay, Human) |
Bioassay |
Human |
| Aldinucci D, 2019, Poletto D, Gloghini A, Nanni P, Degan M, Perin T, Ceolin P, Rossi FM, Gattei V, Carbone A, Pinto A Expression of functional interleukin-3 receptors on Hodgkin and Reed-Sternberg cells. 439, 2002-02-01;160(2):585-96. 2002-02-01 [PMID: 11839579] (Bioassay, Human) |
Bioassay |
Human |
| Shih CC, Hu MC, Hu J A secreted and LIF-mediated stromal cell-derived activity that promotes ex vivo expansion of human hematopoietic stem cells. Blood, 2000-03-15;95(6):1957-66. 2000-03-15 [PMID: 10706861] (Bioassay, Human) |
Bioassay |
Human |
| Gomez-Navarro J, ¯&h~²@á, Contreras JL, Arafat W, Jiang XL, Krisky D, Oligino T, Marconi P, Hubbard B, Glorioso JC, Curiel DT, Thomas JM Genetically modified CD34+ cells as cellular vehicles for gene delivery into areas of angiogenesis in a rhesus model. 2000-01-01;7(1):43-52. 2000-01-01 [PMID: 10680015] (Bioassay, Primate - Macaca mulatta (Rhesus Macaque)) |
Bioassay |
Primate - Macaca mulatta (Rhesus Macaque) |
| Barcena A, Park SW, Banapour B, Muench MO, Mechetner E Expression of Fas/CD95 and Bcl-2 by primitive hematopoietic progenitors freshly isolated from human fetal liver. Blood, 1996-09-15;88(6):2013-25. 1996-09-15 [PMID: 8822920] (Bioassay, Human) |
Bioassay |
Human |
| Romani N, Gruner S, Brang D, Kampgen E, Lenz A, Trockenbacher B, Konwalinka G, Fritsch P, Steinman R, Schuler G Proliferating dendritic cell progenitors in human blood. J Exp Med, 1994-07-01;180(1):83-93. 1994-07-01 [PMID: 8006603] (Bioassay, Human) |
Bioassay |
Human |
|
Show All 195 Publications.
Collapse Publications.
|
![Bioactivity GM-CSF [Unconjugated]](https://images.novusbio.com/images/protein/7954-gmcf_recombinant-human-gm-csf-cho-expressed-protein-cf-bioactivity-272020121514.jpg)
![N/A IL-6 [HRP]](https://images.novusbio.com/images2/DATA_IL6_M6000_ELISA_936.jpg)
![N/A IL-6 [HRP]](https://images.novusbio.com/images2/IL-6_M6000_ELISA_415.jpg)
![N/A IL-6 [HRP]](https://images.novusbio.com/images/m6000b_mouse-il-6-quantikine-elisa-kit-44202415433118.jpg)
![Bioactivity IL-4 [Unconjugated]](https://images.novusbio.com/images/protein/6507-ilcf_recombinant-human-il-4-cho-expressed-protein-cf-bioactivity-272020133214.jpg)
![Bioactivity IL-2 [Unconjugated]](https://images.novusbio.com/images/202-il_recombinant-human-il-2-protein-bioactivity-174202314946.jpg)
![N/A Erythropoietin/EPO [HRP]](https://images.novusbio.com/images2/DATA_Erythropoietin_MEP00_ELISA_970.jpg)
![N/A Erythropoietin/EPO [HRP]](https://images.novusbio.com/images2/Erythropoietin_MEP00_ELISA_421.jpg)
![N/A IL-5 [HRP]](https://images.novusbio.com/images2/IL-5_M5000_ELISA_237.jpg)
![N/A IL-5 [HRP]](https://images.novusbio.com/images2/DATA_IL5_M5000_ELISA_935.jpg)
![SDS-PAGE TNF-alpha [Unconjugated]](https://images.novusbio.com/images2/TNF-alpha_210-TA_256.jpg)
![Bioactivity TNF-alpha [Unconjugated]](https://images.novusbio.com/images2/TNFalpha_210TA_1658.jpg)
![SEC-MALS TNF-alpha [Unconjugated]](https://images.novusbio.com/images/210-ta_recombinant-human-tnf-alpha-protein-sec-mals-35202312244..jpg)
![Neutralization G-CSF Antibody (67604) [Unconjugated]](https://images.novusbio.com/images2/G-CSF_MAB414_Block_Neutralize_9188.jpg)
![Immunohistochemistry CD34 Antibody [Unconjugated]](https://images.novusbio.com/images2/CD34_AF4117_Immunohistochemistry_6824.jpg)
![Bioactivity Thrombopoietin/THPO [Unconjugated]](https://images.novusbio.com/images/protein/288-tpncf_recombinant-human-thrombopoietin-ns0-expressed-protein-cf-bioactivity-272020135047.jpg)
![SDS-PAGE IL-1 beta/IL-1F2 [Unconjugated]](https://images.novusbio.com/images2/IL-1_beta_201-LB_304.jpg)
![Bioactivity IL-1 beta/IL-1F2 [Unconjugated]](https://images.novusbio.com/images2/IL-1_beta_201-LB_306.jpg)
![SEC-MALS IL-1 beta/IL-1F2 [Unconjugated]](https://images.novusbio.com/images/201-lb_recombinant-human-il-1-beta-il-1f2-protein-sec-mals-123202491556.jpg)
![Bioactivity IFN-gamma [Unconjugated]](https://images.novusbio.com/images2/IFNgamma_285IF_2848.jpg)
![SDS-PAGE IFN-gamma [Unconjugated]](https://images.novusbio.com/images2/IFN-gamma_285-IF_230.jpg)
![SEC-MALS IFN-gamma [Unconjugated]](https://images.novusbio.com/images/285-if_recombinant-human-ifn-gamma-protein-sec-mals-1520239228..jpg)
![N/A TIMP-1 [HRP]](https://images.novusbio.com/images2/DATA_TIMP1_DTM100_ELISA_847.jpg)
![N/A TIMP-1 [HRP]](https://images.novusbio.com/images2/TIMP-1_DTM100_ELISA_194.jpg)
![Bioactivity CTLA-4 [Unconjugated]](https://images.novusbio.com/images2/CTLA4_7268CT_2293.jpg)