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Rad21 Antibody (CM110-2C10) [DyLight 550]

Name: Rad21 Antibody (CM110-2C10) [DyLight 550]
Brand: Novus Biologicals
SKU: NB100-386R
Price: 499 USD

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Product Details

Summary

Reactivity	Hu, MuSpecies Glossary
Applications	WB, Simple Western
Clone	CM110-2C10
Clonality	Monoclonal
Host	Mouse
Conjugate	DyLight 550

Order Details

View Available Conjugates

Catalog# & Conjugate	Size	Price
Alexa Fluor 350 NB100-386AF350

Alexa Fluor 405 NB100-386AF405

Alexa Fluor 488 NB100-386AF488

Alexa Fluor 532 NB100-386AF532

Alexa Fluor 594 NB100-386AF594

Alexa Fluor 647 NB100-386AF647

Alexa Fluor 700 NB100-386AF700

Alexa Fluor 750 NB100-386AF750

Allophycocyanin NB100-386APC

Biotin NB100-386B

CoraFluor 1 NB100-386CL1

DyLight 350 NB100-386UV

DyLight 405 NB100-386V

DyLight 488 NB100-386G

DyLight 594 NB100-386DL594

DyLight 650 NB100-386C

DyLight 680 NB100-386FR

DyLight 755 NB100-386IR

HRP NB100-386H

Janelia Fluor 525 NB100-386JF525

Janelia Fluor 549 NB100-386JF549

Janelia Fluor 585 NB100-386JF585

Janelia Fluor 635 NB100-386JF635

Janelia Fluor 646 NB100-386JF646

Janelia Fluor 669 NB100-386JF669

PE NB100-386PE

PerCP NB100-386PCP

Unconjugated NB100-386

mFluor Violet 450 SE NB100-386MFV450

mFluor Violet 500 SE NB100-386MFV500

mFluor Violet 610 SE NB100-386MFV610

View Available Formulations

Catalog# & Formulation	Size	Price
Standard Formulation NB100-386

BSA Free NB100-386

BSA Free NB100-386SS

Azide and BSA Free NBP2-80922

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Conjugate	Catalog #	Availability	Size	Price
Alexa Fluor 350	NB100-386AF350
Alexa Fluor 405	NB100-386AF405
Alexa Fluor 488	NB100-386AF488
Alexa Fluor 532	NB100-386AF532
Alexa Fluor 594	NB100-386AF594
Alexa Fluor 647	NB100-386AF647
Alexa Fluor 700	NB100-386AF700
Alexa Fluor 750	NB100-386AF750
Allophycocyanin	NB100-386APC
Biotin	NB100-386B
CoraFluor 1	NB100-386CL1
DyLight 350	NB100-386UV
DyLight 405	NB100-386V
DyLight 488	NB100-386G
DyLight 594	NB100-386DL594
DyLight 650	NB100-386C
DyLight 680	NB100-386FR
DyLight 755	NB100-386IR
HRP	NB100-386H
Janelia Fluor 525	NB100-386JF525
Janelia Fluor 549	NB100-386JF549
Janelia Fluor 585	NB100-386JF585
Janelia Fluor 635	NB100-386JF635
Janelia Fluor 646	NB100-386JF646
Janelia Fluor 669	NB100-386JF669
PE	NB100-386PE
PerCP	NB100-386PCP
Unconjugated	NB100-386
mFluor Violet 450 SE	NB100-386MFV450
mFluor Violet 500 SE	NB100-386MFV500
mFluor Violet 610 SE	NB100-386MFV610

Rad21 Antibody (CM110-2C10) [DyLight 550] Summary

Immunogen	An N-terminal fusion protein of the C-terminal fragment of Scc1 subunit human cohesin (amino acids 544-631 of hRad21).
Localization	Nuclear and cytoplasm
Specificity	NB100-386 is specific for both the nuclear hRad21 protein and the cleaved cytoplasmic hRad21 protein.
Isotype	IgG1 Kappa
Clonality	Monoclonal
Host	Mouse
Gene	RAD21
Purity	Protein G purified
Innovator's Reward	Test in a species/application not listed above to receive a full credit towards a future purchase. Learn about the Innovator's Reward

Applications/Dilutions

Dilutions	Simple Western Western Blot
Application Notes	Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage	Store at 4C in the dark.
Buffer	50mM Sodium Borate
Preservative	0.05% Sodium Azide
Purity	Protein G purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Rad21 Antibody (CM110-2C10) [DyLight 550]

double-strand-break repair protein rad21 homolog
hHR21FLJ25655
HR21
KIAA0078RAD21 (S. pombe) homolog
MCD1
Nuclear matrix protein 1
NXP-1
NXP1HRAD21
protein involved in DNA double-strand break repair
RAD21 homolog (S. pombe)
SCC1 homolog
SCC1FLJ40596

Background

The cohesin complex plays an important role in tethering sister chromatids during the prophase through anaphase stages of mitosis, making certain that genomic information is replicated accurately. As the cellular division process continues, separase destroys the cohesin complex by means of cleavaging its Scc1 subunit (Mcd1/Scc1/hRad21), allowing the chromatids to separate and divide with the cell. During apoptosis the C-terminal portion of hRad21 is cleaved and translocated to the cytoplasm. This cleavage and translocation may act as a nuclear signal that promotes and accelerates subsequent events of apoptosis (2).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Rad21 Antibody
(CM110-2C10) [DyLight ...

NB100-386R

Species: Hu, Mu

Applications: WB, Simple Western

Publications for Rad21 Antibody (NB100-386R) (0)

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Bioinformatics

Gene Symbol

RAD21

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At	=	A. thaliana	SyHa	=	Golden Syrian Hamster
All	=	All Species	Ha	=	Hamster
An	=	Animal	Hu	=	Human
ArHa	=	Armenian Hamster	I	=	Insect
Av	=	Avian	Ll	=	Llama
Bb	=	Baboon	Ma	=	Mammal
Ba	=	Bacteria	Mk	=	Monkey
Bv	=	Bovine	Mu	=	Mouse
Ca	=	Canine	Multi	=	Multi-species
Ce	=	C. Elegans	NA	=	Non-species specific
Ch	=	Chicken	Or	=	Orangutan
ChHa	=	Chinese Hamster	Pl	=	Plant
Cm	=	Cynomolgus Monkey	Pm	=	Primate
Do	=	Donkey	Po	=	Porcine
Dr	=	Drosophilia	Rb	=	Rabbit
Ec	=	E. Coli	Rt	=	Rat
Eq	=	Equine	RM	=	Rhesus Macaque
Fe	=	Feline	Sh	=	Sheep
Ft	=	Ferret	Vb	=	Vertebrate
Fi	=	Fish	Vi	=	Virus
Fu	=	Fungi	Xp	=	Xenopus
Ge	=	Gerbil	Ye	=	Yeast
GP	=	Guinea Pig	Ze	=	Zebrafish
Gt	=	Goat

Rad21 Antibody (CM110-2C10) [DyLight 550]

Species Glossary

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Product Details

Order Details

Rad21 Antibody (CM110-2C10) [DyLight 550] Summary

Applications/Dilutions

Packaging, Storage & Formulations

Notes

Alternate Names for Rad21 Antibody (CM110-2C10) [DyLight 550]

Background

Limitations

Customers Who Viewed This Item Also Viewed...

Publications for Rad21 Antibody (NB100-386R) (0)

Reviews for Rad21 Antibody (NB100-386R) (0)

Product General Protocols

Video Protocols

FAQs for Rad21 Antibody (NB100-386R) (0)

Secondary Antibodies

Isotype Controls

Additional Rad21 Products

Research Areas for Rad21 Antibody (NB100-386R)

Blogs on Rad21

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Bioinformatics