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Quantikine Immunoassay Control Set 651 for Human TIMP-1

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA, Ctrl
Conjugate
Unconjugated

Order Details

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Quantikine Immunoassay Control Set 651 for Human TIMP-1 Summary

Additional Information
For use with catalog numbers DTM100, STM100, PDTM100
Source
N/A
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
TIMP1

Applications/Dilutions

Dilutions
  • Control
  • ELISA

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Quantikine Immunoassay Control Set 651 for Human TIMP-1

  • CLGI
  • Collagenase inhibitor
  • collagenase inhibitor)
  • EPATIMP-1
  • EPO
  • erythroid potentiating activity
  • Erythroid-potentiating activity
  • Fibroblast collagenase inhibitor
  • FLJ90373
  • HCI
  • metalloproteinase inhibitor 1
  • TIMP metallopeptidase inhibitor 1
  • TIMP1
  • TIMP-1
  • TIMPtissue inhibitor of metalloproteinase 1 (erythroid potentiating activity
  • Tissue inhibitor of metalloproteinases 1

Background

TIMPs-1 through -4 regulate the activity of zinc metalloproteases known as MMPs, ADAMs and ADAMTSs. Structurally, TIMPs contain two domains. The N-terminal domain binds to the active site of mature metalloproteases via a 1:1 non-covalent interaction, blocking access of substrates to the catalytic site. In addition, The C-terminal domain of TIMP-1 and TIMP-2 binds to the hemopexin- like domain of pro-MMP-9 and pro-MMP-2, respectively. The latter binding is essential for the cell surface activation of MMP-2 by MMP-14.

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Immunohistochemistry MMP-1 Antibody (36665) [Unconjugated]
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N/A MMP-3 [HRP]
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IL-3 [Unconjugated]
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Erythropoietin R
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SCF/c-kit Ligand
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GM-CSF
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7954-GM/CF
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Applications: BA
Quantikine
Immunoassay Control S ...
QC173
Quantikine Immunoassay Control Set 651 for Human TIMP-1
Species: Hu
Applications: ELISA, Ctrl

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Product General Protocols

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FAQs for TIMP-1 (QC173) (0)

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Western blot shows lysates of PC-3 human prostate cancer cell line, HT-29 human colon adenocarcinoma cell line, and SK-OV-3 human ovarian adenocarcinoma cell line. PVDF membrane was probed with 5 µg/mL of Goat Anti-Human TIMP-1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF970) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF017). A specific band was detected for TIMP-1 at approximately 26 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.
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Bioinformatics

Gene Symbol TIMP1