PTH Antibody (BGN/1F8) [HRP] Summary
Description |
This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet. |
Immunogen |
Synthetic peptide corresponding to amino acids 1-34 of mature PTH conjugated to a proprietary carrier molecule |
Specificity |
2 x 10^7with 1-34 PTH, 5 x 10^8 with 1-84 PTH |
Isotype |
IgG1 |
Clonality |
Monoclonal |
Host |
Mouse |
Gene |
PTH |
Purity |
Protein A purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- ELISA
- Immunocytochemistry/ Immunofluorescence
- Immunohistochemistry
- Immunohistochemistry-Frozen
- Immunohistochemistry-Paraffin
|
Application Notes |
Optimal dilution of this antibody should be experimentally determined. |
Publications |
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Reactivity Notes
Predicted cross-reactivities: Mouse, Rat
Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.
Packaging, Storage & Formulations
Storage |
Store at 4C in the dark. |
Buffer |
PBS |
Preservative |
No Preservative |
Purity |
Protein A purified |
Alternate Names for PTH Antibody (BGN/1F8) [HRP]
Background
Parathyroid hormone (PTH), which is also designated parathyrin, is an 84 amino acid single chain peptide that functions to regulate calcium metabolism by raising blood levels of calcium through various mechanisms. PTH stimulates bone formation to increase bone mass and strength in rats and humans. Within the PTH molecule, the essential activity is associated with the first 34 amino acids at the amino-terminus of the molecule. The gene encoding PTH maps to human chromosome 11p15.3-p15.1. Parathyroid hormone-related protein (PTH-rP) is an autocrine factor that is structurally related to PTH yet, unlike PTH, which is synthesized only by the parathyroid cells, PTH-rP is synthesized by several cell types. PTH-rP regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. Isolated from the culture medium of a human lung cancer cell line, PTH-rP produces PTH-like effects that are characterized as humoral hypercalcemia of malignancy.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Publications for PTH Antibody (NB100-65676H)(1)
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Product General Protocols
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Video Protocols
FAQs for PTH Antibody (NB100-65676H). (Showing 1 - 1 of 1 FAQ).
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I was wondering if you would be able to confirm that the epitopes of your PTH antibodies NBP2-54320H and NB100-65676H are in the AA 7-33 region?
- Both NB100-65676H & NBP2-54320H are generated against a synthetic peptide corresponding to amino acids 1 to 34 of mature PTH conjugated to a carrier molecule. Although we havent done any epitope mapping analysis, based on the immunogen sequence, we can confirm you that the epitopes of these antibodies are within AA 1-33 of parathyroid hormone (PTH) protein.
Secondary Antibodies
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