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PTGER2 Antibody (607077)

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PTGER2 was detected in immersion fixed paraffin-embedded sections of human bladder using Human PTGER2 Monoclonal Antibody (Catalog # MAB6656) at 25 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Mouse ...read more
Western blot shows lysates of MCF-7 human breast cancer cell line. PVDF Membrane was probed with 2 µg/mL of Human PTGER2 Monoclonal Antibody (Catalog # MAB6656) followed by HRP-conjugated Anti-Mouse IgG Secondary ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clone
607077
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
LYOPH

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PTGER2 Antibody (607077) Summary

Immunogen
NS0 mouse myeloma cell line transfected with human PTGER2
Accession # P43116
Specificity
Detects human PTGER2 in direct ELISAs.
Source
N/A
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
PTGER2
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 8-25 ug/mL
  • Western Blot 2 ug/mL
Reviewed Applications
Read 1 Review rated 4
using
MAB6656 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Sterile PBS to a final concentration of 0.5 mg/mL.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for PTGER2 Antibody (607077)

  • EP2
  • PGE receptor EP2 subtype
  • PGE2 receptor EP2 subtype
  • prostaglandin E receptor 2 (subtype EP2), 53kD
  • prostaglandin E receptor 2 (subtype EP2), 53kDa
  • prostaglandin E2 receptor EP2 subtype
  • Prostanoid EP2 receptor
  • PTGER2

Background

Prostaglandin E2 receptor (PTGER2) is a 53 kDa member of the G-protein coupled receptor family of proteins. Human PTGER2 is 358 amino acids (aa) in length and has the seven putative transmembrane domains characteristic of G-protein coupled receptors. In addition, there are four potential sites for N-linked glycosylation.  Human PTGER2 shares 86% and 83% aa sequence identity with mouse and rat PTGER2, respectively. PTGER2 is present in the vasculature, the gastrointestinal, tracheobronchial, and reproductive tracts, the kidney, and also in the sphincter, dilator, and ciliary muscles in the eye.  PTGER2 is linked to prostaglandin E2-mediated vasodilation and smooth muscle relaxation. It is also involved in the stimulation of secretion in the stomach and small intestine, the control of intraocular pressure, and the regulation of bone resorption.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for PTGER2 Antibody (MAB6656) (0)

There are no publications for PTGER2 Antibody (MAB6656).
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Review for PTGER2 Antibody (MAB6656) (1) 41

Average Rating: 4
(Based on 1 review)
We have 1 review tested in 1 species: Human.

Reviews using MAB6656:
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IF
(1)
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(1)
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Images Ratings Applications Species Date Details
Immunofluorescence PTGER2 MAB6656
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4
reviewed by:
Jan Martinek
IF Human 01/17/2018
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Summary

ApplicationImmunofluorescence
Sample TestedHuman Tonsil tissue
SpeciesHuman
LotCEISO21712A

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Recent Reviews

4
5
0
4
1
3
0
2
0
1
0

Jan Martinek
01/17/2018
Application: IF
Species: Human

Bioinformatics

Gene Symbol PTGER2
Uniprot