PPP2R3A Antibody

PPP2R3A is a gene that codes for a protein with three isoforms, with lengths of 1150, 529, and 414 amino acids and weights of approximately 130, 61, and 48 kDa respectively. PPP2R3A is thought to modulate substrate selectivity and catalytic activity, as well as facilitate in the localization of catalytic enzymes. Current studies are being done on diseases and disorders related to this gene including retinoblastoma, ataxia, immunodeficiency, malaria, neuronitis, and breast cancer. PPP2R3A has also been shown to have interactions with ATXN7L2, PPP2CA, PPP5C, CDC6, and PPP2R1A in pathways such as the signal transduction PKA signaling, CDK5, mTOR, cell cycle regulation, Wnt signaling, glycogen metabolism, and IL-6 signaling pathways.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 2 applications: WB, Western Blot.

Showing Publications 1 - 5 of 5.

Publications using NBP1-87233	Applications	Species
Nguyen A, Leydecker A, Mustafa A et al. The protein phosphatase-2A subunit PR130 is linked to cytotoxic protein aggregate formation in mesenchymal pancreatic ductal adenocarcinoma cells bioRxiv 2023-09-05 (WB, Human)	WB	Human
Nguyen A, Dzulko M, Murr J et al. Class 1 Histone Deacetylases and Ataxia-Telangiectasia Mutated Kinase Control the Survival of Murine Pancreatic Cancer Cells upon dNTP Depletion Cells 2021-09-23 [PMID: 34685500] (Western Blot)	Western Blot
DeGrande ST, Little SC, Nixon DJ et al. Molecular Mechanisms Underlying Cardiac Protein Phosphatase 2A Regulation in Heart. J Biol Chem 2013-01-11 [PMID: 23204520]
Nguyen A, Leydecker A, Mustafa A et al. The protein phosphatase-2A subunit PR130 is involved in the formation of cytotoxic protein aggregates in pancreatic ductal adenocarcinoma cells Research Square 2023-11-15
Goder A, Emmerich C, Nikolova T, Kiweler N. HDAC1 and HDAC2 integrate checkpoint kinase phosphorylation and cell fate through the phosphatase-2A subunit PR130. Nat Commun. 2018-02-22 [PMID: 29472538]

Array NBP1-87233

• PPP2R3A Antibodies
• PPP2R3A Lysate
• PPP2R3A Proteins