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PPP2CB Antibody

Images

 
Western Blot: PPP2CB Antibody [H00005516-B01P] - Analysis of PPP2CB expression in transfected 293T cell line by PPP2CB polyclonal antibody. Lane 1: PPP2CB transfected lysate(34.1 KDa). Lane 2: Non-transfected lysate.
Immunocytochemistry/ Immunofluorescence: PPP2CB Antibody [H00005516-B01P] - Analysis of purified antibody to PPP2CB on HeLa cell. (antibody concentration 10 ug/ml)

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ICC/IF
Clonality
Polyclonal
Host
Mouse
Conjugate
Unconjugated

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PPP2CB Antibody Summary

Description
Quality control test: Antibody reactive against mammalian transfected lysate.
Immunogen
PPP2CB (AAH12022, 1 a.a. - 309 a.a.) full-length human protein. MDDKAFTKELDQWVEQLNECKQLNENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYFL
Isotype
IgG
Clonality
Polyclonal
Host
Mouse
Gene
PPP2CB
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot
Application Notes
It has been used for WB and Functional.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
Protein G purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for PPP2CB Antibody

  • EC 3.1.3.16
  • PP2Abeta
  • PP2A-beta
  • PP2CB
  • protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform
  • protein phosphatase 2, catalytic subunit, beta isoform
  • protein phosphatase 2, catalytic subunit, beta isozyme
  • protein phosphatase 2A catalytic subunit, beta isoform
  • protein phosphatase type 2A catalytic subunit
  • serine/threonine protein phosphatase 2A, catalytic subunit, beta isoform
  • serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

Background

PPP2CB also known as Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform, is a 309 amino acid protein that is 36 kDa, localizes in cytoplasm and nucleus, is implicated in the negative control of cell growth and division and modulates the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Studies of this protein are being done on the following diseases and disorders: cerebral cavernous malformations, cavernous malformation, cerebral cavernous malformations 3, Werner syndrome, Chagas disease, hepatitis c, trypanosomiasis, cerebritis, Alzheimer's disease, prostate cancer, hepatitis, prostatitis, immunodeficiency, malaria, neuronitis, and breast cancer. PPP2CB protein has been linked to Neurophysiological process Glutamate regulation of Dopamine D1A receptor signaling, Signal transduction Calcium signaling, Development Beta-adrenergic receptors signaling via cAMP,Cell cycle Regulation of G1/S transition (part 1), Cell cycle Start of DNA replication in early S phase, Cell Cycle Control by BTG Proteins, CDK5 Pathway, mTOR Pathway, AMPK Enzyme Complex Pathway, Cyclins and Cell Cycle Regulation, Akt Pathway, Insulin Pathway, TGF-beta Pathway, Wnt Pathway, Apoptosis and survival BAD phosphorylation, and many other pathways where interacts with HIST1H4B , HIST1H4A, HIST1H4C, HIST1H4D, HIST1H4E, AXIN2, and over 280 other interacting proteins.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol PPP2CB
Uniprot