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PP14/Glycodelin Antibody (16) [Janelia Fluor® 525]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA, IHC
Clone
16
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 525

Order Details

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PP14/Glycodelin Antibody (16) [Janelia Fluor® 525] Summary

Immunogen
Placental protein 14 (glycodelin A) purified from second trimester amniotic fluid
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
PAEP
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for PP14/Glycodelin Antibody (16) [Janelia Fluor® 525]

  • alpha uterine protein
  • GdF
  • GdS
  • Glycodelin
  • glycodelin-A
  • glycodelin-F
  • glycodelin-S
  • MGC138509
  • MGC142288
  • PAEP
  • PEP
  • Placental protein 14
  • PP14 protein (placental protein 14)
  • PP14
  • PP14GDPAEGGdA
  • pregnancy-associated endometrial a
  • Pregnancy-associated endometrial alpha-2 globulin
  • pregnancy-associated endometrial alpha-2-globulin
  • progestagen-associated endometrial protein (placental protein 14
  • progestagen-associated endometrial proteinPEG
  • Progesterone-associated endometrial protein

Background

PAEP (Progesterone-associated endometrial protein, glycodelin, PEG, PP14) is a glycoprotein belonging to lipocalin structural superfamily. It shares a sequence homology to beta-lactoglobulins containing a retinol-binding motif and it is mainly produced by secretory and decidualized endometrium in women and by seminal vesicle epithelium in men (1). PAEP function is not clearly understood. However, glycosylated version of PAEP (GdA) has been associated to contraceptive and immunosuppressive activities during reproduction. PAEP is the main protein produced by secretory endometrium during mid-luteal phase of the menstrual cycle and during the first semester of pregnancy. Therefore, PAEP has been linked as an ideal biomarker of endometrial activity and function for in vitro fertilization treated women (2).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol PAEP