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Podoplanin Antibody (PDPN/4009R) [FITC]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA, ICC/IF, IHC
Clone
PDPN/4009R
Clonality
Monoclonal
Host
Rabbit
Conjugate
FITC

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Podoplanin Antibody (PDPN/4009R) [FITC] Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
Synthetic peptide corresponding to residues within aa1-100 of Podoplanin (Uniprot: Q86YL7)
Localization
Cell Surface
Marker
Lymphatic Endothelial & Mesothelial Marker
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
PDPN
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Alternate Names for Podoplanin Antibody (PDPN/4009R) [FITC]

  • 36-KD
  • Aggrus
  • Gp36
  • Gp38
  • GP40
  • HT1A-1
  • hT1alpha-1
  • hT1alpha-2
  • lung type I cell membrane associated glycoprotein
  • lung type-I cell membrane-associated glycoprotein (T1A-2)
  • OTS 8
  • OTS8
  • PA2.26 antigen
  • PDPN
  • Podoplanin
  • RANDAM-2
  • T1A
  • T1A-2
  • T1-alpha

Background

Podoplanin is a well-recognized lymphatic endothelium marker, which can be used to reliably distinguish lymphatic vessels from blood vessels. Podoplanin is a 38 kDa membrane mucoprotein that was originally detected on the surface of rat glomerular epithelial cells (podocytes) and was found to be linked to flattening of foot processes that occurs in glomerular diseases. Podoplanin shows features of a membrane mucoprotein with several conserved O-glycosylation sites. Currently, it is of unknown biological function. Because heavily O-glycosylated mucoproteins were identified recently as counterreceptors for selectins that mediate adhesion of inflammatory cells, it is possible that podoplanin plays a similar role in lymphatic endothelia.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol PDPN