Podoplanin Products

Description

Podoplanin is a well-recognized lymphatic endothelium marker, which can be used to reliably distinguish lymphatic vessels from blood vessels. Podoplanin is a 38 kDa membrane mucoprotein that was originally detected on the surface of rat glomerular epithelial cells (podocytes) and was found to be linked to flattening of foot processes that occurs in glomerular diseases. Podoplanin shows features of a membrane mucoprotein with several conserved O-glycosylation sites. Currently, it is of unknown biological function. Because heavily O-glycosylated mucoproteins were identified recently as counterreceptors for selectins that mediate adhesion of inflammatory cells, it is possible that podoplanin plays a similar role in lymphatic endothelia.

Bioinformatics

Entrez	10630 Human 14726 Mouse 54320 Rat
Uniprot	AAH22812.2 Human NM_198389 Human NP_006465 Human NP_006465.3 Human Q62011 Mouse Q64294 Rat Q86YL7 Human Q86YL7-3 Human
Product By Gene ID	10630
Alternate Names	36-KD Aggrus AGGRUS aggrus Gp36 GP40 HT1A-1 hT1alpha-1 hT1alpha-2 lung type I cell membrane associated glycoprotein lung type-I cell membrane-associated glycoprotein (T1A-2) OTS 8 OTS8 PA2.26 antigen podoplanin T1A T1-alpha

Research Areas for Podoplanin

Find related products by research area and learn more about each of the different research areas below.

Core ESC-Like Genes
Signal Transduction
Stem Cell Markers

Related Podoplanin Blog Posts

Check out the latest blog posts on Podoplanin.

Meningeal lymphatics: recent discovery defying the concept of central nervous system 'immune privilege' By Jennifer Sokolowski, MD, PhD. Identification and characterization of meningeal lymphaticsThe recent discovery of a lymphatic system in the meninges surrounding the brain and spinal cord has spurred a surge of int...    Read more.

Podoplanin (OST8, Glycoprotein (Gp) 36 or 38, Lung Type I Cell Membrane Associated Glycoprotein) Podoplanin is a mucin-type 1 transmembrane glycoprotein found in a wide range of tissues. It appears to be differentially expressed in endothelial cells of lymphatic but not blood vessel origin. In normal skin and kidney, podoplanin co-localizes with ...    Read more.

Spheroids vs. Organoids: Which 3D Cell Culture Model is Best for You? By Jennifer Jones, M.S.Spheroids and organoids are two words that, like “butter” and “margarine”, are often referred to interchangeably but have distinct meanings. The progression and adopt...    Read more.

Read more Podoplanin related blogs.