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Podoplanin Antibody (8.1.1) [Biotin]

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Product Details

Summary
Reactivity Mu, Hu(-)Species Glossary
Applications WB, Flow, ICC/IF, IHC, IP, MS, CyTOF-ready
Clone
8.1.1
Clonality
Monoclonal
Host
Golden Syrian Hamster
Conjugate
Biotin

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB600-1015AF350
Alexa Fluor 405
NB600-1015AF405
Alexa Fluor 488
NB600-1015AF488
Alexa Fluor 532
NB600-1015AF532
Alexa Fluor 594
NB600-1015AF594
Alexa Fluor 647
NB600-1015AF647
Alexa Fluor 700
NB600-1015AF700
Alexa Fluor 750
NB600-1015AF750
Allophycocyanin
NB600-1015APC
CoraFluor 1
NB600-1015CL1
DyLight 350
NB600-1015UV
DyLight 405
NB600-1015V
DyLight 488
NB600-1015G
DyLight 550
NB600-1015R
DyLight 594
NB600-1015DL594
DyLight 650
NB600-1015C
DyLight 680
NB600-1015FR
DyLight 755
NB600-1015IR
FITC
NB600-1015F
HRP
NB600-1015H
Janelia Fluor 525
NB600-1015JF525
Janelia Fluor 549
NB600-1015JF549
Janelia Fluor 646
NB600-1015JF646
Janelia Fluor 669
NB600-1015JF669
PE
NB600-1015PE
PerCP
NB600-1015PCP
Unconjugated
NB600-1015
mFluor Violet 450 SE
NB600-1015MFV450
mFluor Violet 500 SE
NB600-1015MFV500
mFluor Violet 610 SE
NB600-1015MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NB600-1015
BSA Free
NB600-1015SS
BSA Free
NB600-1015
Azide and BSA Free
NBP2-80916
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Podoplanin Antibody (8.1.1) [Biotin] Summary

Immunogen
Murine thymic stromal cell lines
Localization
Membrane; Single-pass type I membrane protein.
Marker
Lymphatic Endothelium Marker
Isotype
IgG
Clonality
Monoclonal
Host
Golden Syrian Hamster
Gene
PDPN
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Electron Microscopy
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
  • Immunoprecipitation
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Readout System

Reactivity Notes

Does not cross-react with human.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Alternate Names for Podoplanin Antibody (8.1.1) [Biotin]

  • 36-KD
  • Aggrus
  • Gp36
  • Gp38
  • GP40
  • HT1A-1
  • hT1alpha-1
  • hT1alpha-2
  • lung type I cell membrane associated glycoprotein
  • lung type-I cell membrane-associated glycoprotein (T1A-2)
  • OTS 8
  • OTS8
  • PA2.26 antigen
  • PDPN
  • Podoplanin
  • RANDAM-2
  • T1A
  • T1A-2
  • T1-alpha

Background

Podoplanin antibody (Clone 8.1.1) is a well-recognized lymphatic endothelium marker, which can be used to reliably distinguish lymphatic vessels from blood vessels. Podoplanin is specifically expressed in the endothelium of lymphatic capillaries but not in the blood vasculature. In normal skin and kidney, podoplanin colocalized with VEGFR3/FLT4, another marker for lymphatic endothelial cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Research Areas for Podoplanin Antibody (NB600-1015B)

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Blogs on Podoplanin.

Check out the latest blog posts on Podoplanin.
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By Jennifer Jones, M.S.Spheroids and organoids are two words that, like “butter” and “margarine”, are often referred to interchangeably but have distinct meanings. The progression and adopt...  Read full blog post.
Meningeal lymphatics: recent discovery defying the concept of central nervous system 'immune privilege'
By Jennifer Sokolowski, MD, PhD. Identification and characterization of meningeal lymphaticsThe recent discovery of a lymphatic system in the meninges surrounding the brain and spinal cord has spurred a surge of int...  Read full blog post.
Podoplanin (OST8, Glycoprotein (Gp) 36 or 38, Lung Type I Cell Membrane Associated Glycoprotein)
Podoplanin is a mucin-type 1 transmembrane glycoprotein found in a wide range of tissues. It appears to be differentially expressed in endothelial cells of lymphatic but not blood vessel origin. In normal skin and kidney, podoplanin co-localizes with ...  Read full blog post.
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Bioinformatics

Gene Symbol PDPN