Plexin C1 Antibody (544232)

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Plexin C1 (also VESPR and CD232) is a 210 kDa member of the plexin-C subfamily, plexin family of proteins. It is a type I transmembrane glycoprotein that is found on monocytes, dendritic cells and neutrophils. Plexin C1 binds Sema7A, and its viral counterpart, vaccinia semaphorin A39R. Ligation induces actin cytoskeletal rearrangement and cell immobilization. Mature human Plexin C1 is 1534 amino acids (aa) in length. It contains a 910 aa extracellular domain (ECD) and a 603 aa cytoplasmic region. The ECD contains one Sema-domain (aa 49-440), two PSI domains (aa 454-605) and two IPT regions (aa 664-842). Over aa 49-161, human Plexin C1 shares 92% aa identity with mouse Plexin C1.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Mouse, Bovine.

We have publications tested in 2 applications: Flow Cytometry, Neutralization.

Showing Publications 1 - 5 of 5.

Publications using MAB3887	Applications	Species
Viventi S, Frausin S, Howden SE et al. In vivo survival and differentiation of Friedreich ataxia iPSC-derived sensory neurons transplanted in the adult dorsal root ganglia Stem cells translational medicine 3/18/2021 [PMID: 33734599]
de Haan W, Oie CI, Benkheil M et al. Unraveling the transcriptional determinants of Liver Sinusoidal Endothelial Cell specialization Am. J. Physiol. Gastrointest. Liver Physiol. 3/2/2020 [PMID: 32116021]
AJ Alshawaf, S Viventi, W Qiu, G D'Abaco, B Nayagam, M Erlichster, G Chana, I Everall, J Ivanusic, E Skafidas, M Dottori Phenotypic and Functional Characterization of Peripheral Sensory Neurons derived from Human Embryonic Stem Cells Sci Rep, 2018-01-12;8(1):603. 1/12/2018 [PMID: 29330377]
Myster F, Palmeira L, Sorel O, Bouillenne F, DePauw E, Schwartz-Cornil I, Vanderplasschen A, Dewals B Viral semaphorin inhibits dendritic cell phagocytosis and migration but is not essential for gammaherpesvirus-induced lymphoproliferation in malignant catarrhal fever. J Virol, 2015-01-14;89(7):3630-47. 2015-01-14 [PMID: 25589653] (Flow Cytometry, Bovine)	Flow Cytometry	Bovine
Kang S, Okuno T, Takegahara N, Takamatsu H, Nojima S, Kimura T, Yoshida Y, Ito D, Ohmae S, You DJ, Toyofuku T, Jang MH, Kumanogoh A Intestinal epithelial cell-derived semaphorin 7A negatively regulates development of colitis via alphavbeta1 integrin. J. Immunol., 2011-12-23;188(3):1108-16. 2011-12-23 [PMID: 22198947] (Flow Cytometry, Neutralization, Mouse)	Flow Cytometry, Neutralization	Mouse

Array MAB3887

• Plexin C1 Antibodies
• Plexin C1 Protein
• Plexin C1 Proteins and Enzymes