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Plexin A1 Antibody (708954) [Janelia Fluor® 646]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, ICC/IF
Clone
708954
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 646

Order Details

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Plexin A1 Antibody (708954) [Janelia Fluor® 646] Summary

Immunogen
E. coli-derived recombinant human Plexin A1
Tyr964-Leu1152
Accession # Q9UIW2
Specificity
Detects human Plexin A1 in direct ELISAs.
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunocytochemistry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Plexin A1 Antibody (708954) [Janelia Fluor® 646]

  • NOV
  • NOVP
  • Plexin A1
  • PLEXIN-A1
  • PLXN1
  • PLXNA1

Background

Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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