Bovine Plasminogen ELISA Kit (Colorimetric) Summary
Description |
This assay employs a quantitative enzyme immunoassay technique that measures the specified antigen in samples. |
Standard Curve Range |
0.75-24 ug/ml (example only; lot dependent) |
Sensitivity |
0.45 ug/ml (example only; lot dependent) |
Assay Type |
Competitive ELISA |
Inter-Assay |
CV% < 10.10% (example only; lot dependent) |
Intra-Assay |
CV% < 5.20% (example only; lot dependent) |
Spike Recovery |
97.00% (example only; lot dependent) |
Kit Type |
ELISA Kit (Colorimetric) |
Gene |
PLG |
Applications/Dilutions
Packaging, Storage & Formulations
Storage |
Storage is content dependent. |
Alternate Names for Bovine Plasminogen ELISA Kit (Colorimetric)
Background
Plasminogen is a plasma protein synthesised mostly in the liver. Plasma concentration is usually in the range of 70 to 200mg/L. Plasminogen is activated by tissue plasminogen activator, urokinase and streptokinase, to form plasmin. Activation results from the cleavage and release of the preactivation peptide. Angiostatin, an internal fragment of plasminogen, is a potent inhibitor of angiogenesis, which selectively inhibits endothelial cell proliferation. Angiostatin potently inhibits tumor growth and can maintain metastatic and primary tumors in a dormant state. It is defined by a balance of proliferation and apoptosis of the tumor cells and is composed of plasminogen first four cringle structures. This molecule is generated by proteolytic cleavage of plasminogen.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are
guaranteed for 6 months from date of receipt.
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