Plasminogen Antibody [Biotin]

Plasminogen is a plasma protein synthesised mostly in the liver. Plasma concentration is usually in the range of 70 to 200mg/l. Plasminogen is activated by tissue plasminogen activator, urokinase and streptokinase, to form plasmin. Activation results from the cleavage and release of the preactivation peptide. Angiostatin, an internal fragment of plasminogen, is a potent inhibitor of angiogenesis, which selectively inhibits endothelial cell proliferation. Angiostatin potently inhibits tumor growth and can maintain metastatic and primary tumors in a dormant state. It is defined by a balance of proliferation and apoptosis of the tumor cells and is composed of plasminogen first four cringle structures. This molecule is generated by proteolytic cleavage of plasminogen.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publication using NB120-7336	Applications	Species
Basile DP, Fredrich K, Weihrauch D, Hattan N, Chilian WM Angiostatin and matrix metalloprotease expression following ischemic acute renal failure. Am J Physiol Renal Physiol. 2004-01-01 [PMID: 15075185]

Array NB120-7336

• Plasminogen Antibodies
• Plasminogen ELISA Kits
• Plasminogen Lysate
• Plasminogen Protein
• Plasminogen Proteins and Enzyme
• Plasminogen ELISA