Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for Phospho-JNK2 (T183/Y185) DuoSet IC ELISA, 2 Plate
c-Jun kinase 2
c-Jun N-terminal kinase 2
EC 2.7.11
EC 2.7.11.24
JNK2
JNK2A
JNK2BETA
JNK2JNK2ALPHA
JNK-55
Jun kinase
MAP kinase 9
MAPK 9
MAPK9
mitogen-activated protein kinase 9
p54a
p54aSAPK
PRKM9JNK2B
SAPK
SAPK1 alpha
Stress-activated protein kinase JNK2
Background
Members of the MAPK family, the c-Jun N-terminal kinases (JNKs) are activated by environmental stresses and inflammatory cytokines. Ten JNK isoforms are created by alternative splicing of mRNA transcripts derived from three genes: JNK1, JNK2, and JNK3. All JNKs are activated by dual phosphorylation; at T183/Y185 for JNK1 and 2, and T221/Y223 for JNK3. Activated JNKs translocate to the nucleus where they regulate the activity of several transcription factors; including the c-Jun component of AP-1 and ATF-2.