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PCYT1B Antibody (F39 P7 F11) [Janelia Fluor® 549]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clone
F39 P7 F11
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 549

Order Details

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PCYT1B Antibody (F39 P7 F11) [Janelia Fluor® 549] Summary

Immunogen
Synthetic Peptide corresponding to the C-Terminus of Human CCT-beta.
Specificity
CCT-beta.
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Mouse
Gene
PCYT1B
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Human

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for PCYT1B Antibody (F39 P7 F11) [Janelia Fluor® 549]

  • CCT B
  • CCTB
  • CCT-betaEC 2.7.7.15
  • choline-phosphate cytidylyltransferase B
  • CT B
  • CTB
  • CTP:phosphocholine cytidylyltransferase B
  • EC 2.7.7
  • phosphate cytidylyltransferase 1, choline, beta isoform
  • phosphate cytidylyltransferase 1, choline, beta
  • Phosphorylcholine transferase B

Background

TCP1 beta is a subunit of a cytosolic hetero-oligomer chaperon that is known to be involved in the folding of actin and tubulin. This protein is a member of the chaperonin family, which includes Escherichia coli GroEL, the mitochondrial heat-shock protein Hsp60, the plastid Rubisco-subunit-binding protein and the archaebacterial protein TF55. These chaperonins assist the folding of proteins upon ATP hydrolysis. Nine different subunits of TCP-1 containing chaperonin complexes from mammalian testis and seven different subunits of mouse F9 cells have been identified. It has been suggested that each CCT subunit has a specific, independent function, as they are highly diverged from each other but conserved from mammals to yeast. The expansion in the number of types of CCT subunit, compared with other chaperonins, has allowed CCT to carry out more complex functions that are required for the folding and assembly of highly evolved eukaryotic proteins.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol PCYT1B