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Pax7 Antibody (PAX7/1187)

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Immunohistochemistry-Paraffin: Pax7 Antibody (PAX7/1187) [NBP2-44588] - Human Testicular Carcinoma stained with PAX7 Monoclonal Antibody (PAX7/1187).
Immunohistochemistry-Paraffin: Pax7 Antibody (PAX7/1187) [NBP2-44588] - Human Testicular Carcinoma stained with PAX7 Monoclonal Antibody (PAX7/1187).
Immunohistochemistry-Paraffin: Pax7 Antibody (PAX7/1187) [NBP2-44588] - Human Rhabdomyosarcoma stained with PAX7 Monoclonal Antibody (PAX7/1187).

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clone
PAX7/1187
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
0.2 mg/ml

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-47922AF350
Alexa Fluor 405
NBP2-47922AF405
Alexa Fluor 488
NBP2-47922AF488
Alexa Fluor 532
NBP2-47922AF532
Alexa Fluor 594
NBP2-47922AF594
Alexa Fluor 647
NBP2-47922AF647
Alexa Fluor 700
NBP2-47922AF700
Alexa Fluor 750
NBP2-47922AF750
Biotin
NBP2-47922B
DyLight 350
NBP2-47922UV
DyLight 405
NBP2-47922V
DyLight 488
NBP2-47922G
DyLight 550
NBP2-47922R
DyLight 594
NBP2-47922DL594
DyLight 650
NBP2-47922C
DyLight 680
NBP2-47922FR
DyLight 755
NBP2-47922IR
FITC
NBP2-47922F
HRP
NBP2-47922H
Janelia Fluor 549
NBP2-47922JF549
Janelia Fluor 646
NBP2-47922JF646
View Available Formulations
Catalog# & Formulation Size Price
Azide and BSA Free
NBP2-47922-0.1mg
IHC-Prediluted
NBP2-48248
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Pax7 Antibody (PAX7/1187) Summary

Description
200ug/ml of antibody purified from Bioreactor Concentrate by Protein A or G. Prepared in 10 mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0 mg/ml. (NBP2-47922)

Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80 C.
Immunogen
Recombinant fragment (aa301-505) of human Pax7 protein (exact sequence is proprietary) (Uniprot: P23759)
Localization
Nuclear
Marker
Rhabdomyosarcoma Marker
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
PAX7
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1-2 ug/ml
Application Notes
Immunohistochemistry (Formalin-fixed): 1-2ug/ml for 30 minutes at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris Buffer with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes.
Optimal dilution for a specific application should be determined.
Theoretical MW
57 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Publications
Read Publication using
NBP2-44588 in the following applications:

Packaging, Storage & Formulations

Storage
Store at 4C.
Buffer
10 mM PBS with 0.05% BSA
Preservative
0.05% Sodium Azide
Concentration
0.2 mg/ml
Purity
Protein A or G purified

Alternate Names for Pax7 Antibody (PAX7/1187)

  • FLJ37460
  • HUP1
  • paired box 7
  • paired box gene 7
  • paired box homeotic gene 7
  • paired box protein Pax-7
  • paired domain gene 7
  • PAX7 transcriptional factor
  • Pax7
  • PAX7B
  • RMS2

Background

PAX7 is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box 7 gene is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Alternative splicing in this gene has produced two known products but the biological significance of the variants is unknown.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Pax7 Antibody (NBP2-44588)(1)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: IF/IHC.


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Bioinformatics

Gene Symbol PAX7
Uniprot