Pax2 Antibody (2E4)

This product is produced by and distributed for Abnova, a company based in Taiwan.

PAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor supressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia. Alternative splicing of this gene results in multiple transcript variants.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Showing Publications 1 - 3 of 3.

Publications using H00005076-M02	Applications	Species
Hou L, Du Y, Zhao C et al. PAX2 may induce ADAM10 expression in renal tubular epithelial cells and contribute to epithelial-to-mesenchymal transition. Int Urol Nephrol 2018-08-16 [PMID: 30117015]
Albanito L, Reddy CE, Musti AM. c-Jun is essential for the induction of Il-1b gene expression in in vitro activated Bergmann glial cells. Glia. 2011-09-21 [PMID: 21948257]
Doberstein K, Pfeilschifter J, Gutwein P. The transcription factor PAX2 regulates ADAM10 expression in renal cell carcinoma. Carcinogenesis. 2011-09-16 [PMID: 21880579]

Array H00005076-M02

• Pax2 Antibodies
• Pax2 Lysates
• Pax2 Proteins