PAK7 Antibody (444703)

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

PAK7 (p21-activated kinase 7), also called PAK5, is a neuronal member of the PAK-II subfamily within the STE Ser/Thr protein kinase family. In the portion used as immunogen, human PAK7 shares 95% aa sequence identity with rat PAK7. This portion contains a CDC42/Rac1 interactive binding (CRIB) motif and potential phosphorylation sites at Ser104 and Thr107. In addition, PAK7 also interacts with RhoD and RhoH, directing its subcellular localization. PAK7 can be located in the mitochondrion, where it protects cells from apoptosis, or in the nucleus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 2 applications: IHC, Western Blot.

Showing Publications 1 - 3 of 3.

Publications using MAB4696	Applications	Species
Y Xing, Y Li, B Hu, F Han, X Zhao, H Zhang, Y Li, D Li, J Li, F Jin, F Li PAK5-mediated AIF phosphorylation inhibits its nuclear translocation and promotes breast cancer tumorigenesis International journal of biological sciences, 2021-03-27;17(5):1315-1327. 2021-03-27 [PMID: 33867848] (IHC, Human)	IHC	Human
Y Wang, C Gratzke, A Tamalunas, N Wiemer, A Ciotkowska, B Rutz, R Waidelich, F Strittmatt, C Liu, CG Stief, M Hennenberg P21-Activated Kinase Inhibitors FRAX486 and IPA3: Inhibition of Prostate Stromal Cell Growth and Effects on Smooth Muscle Contraction in the Human Prostate PLoS ONE, 2016-04-12;11(4):e0153312. 2016-04-12 [PMID: 27071060] (Western Blot, Human)	Western Blot	Human
G Zhu, X Li, B Guo, Q Ke, M Dong, F Li PAK5-mediated E47 phosphorylation promotes epithelial–mesenchymal transition and metastasis of colon cancer Oncogene 4/14/2016 [PMID: 26212009]

Array MAB4696

• PAK7 Antibodies
• PAK7 Lysates
• PAK7 Proteins