PAK6 Antibody - BSA Free

PAK6, a PAK (STE20) type protein kinase, contains a N-terminal Cdc42/Rac interactive binding (CRIB) motif and a C-terminal kinase domain. The protein has been shown to bind to GTP-Cdc42 and GTP-Rac; however, in contrast to most PAKs, kinase activity was not stimulated by Cdc42 or Rac, but could be stimulated by androgen receptor (AR) binding. PAK6 protein also has been shown to bind to estrogen receptor alpha. PAK6 expression has been documented in normal human brain, breast, prostate and testis. ESTs have been isolated from several tissue libraries, including normal brain and testis and cancerous cervix and smooth muscle. Caution: PAK6 also has been called P21-Activated Kinase 5 (PAK5); however, PAK5 is a distinct gene found on chromosome 20 p12.2.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: IF/IHC.

Showing Publication 1 - 1 of 1.

Publication using NLS6942	Applications	Species
Kwek SS, Dao V, Roy R et al. Diversity of Antigen-Specific Responses Induced In Vivo with CTLA-4 Blockade in Prostate Cancer Patients J Immunol 2012-10-01 [PMID: 22956585] (IF/IHC, Human)	IF/IHC	Human

Array NLS6942

• PAK6 Antibodies
• PAK6 Lysates
• PAK6 Proteins