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p70 S6 Kinase beta/S6K2 Antibody

Images

 
Western Blot: p70 S6 Kinase beta/S6K2 Antibody [NBP1-87805] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells) Lane 2: NBT-II cell lysate (Rat Wistar bladder tumour cells)
Immunohistochemistry-Paraffin: p70 S6 Kinase beta/S6K2 Antibody [NBP1-87805] - Staining of human esophagus shows nuclear and cytoplasmic positivity in squamous epithelial cells.
Western Blot: p70 S6 Kinase beta/S6K2 Antibody [NBP1-87805] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-412

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

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p70 S6 Kinase beta/S6K2 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: VDSPDDTALSESANQAFLGFTYVAPSVLDSIKEGFSFQPKLRSPRRLNSSPRAPVSPLKFSPFEGFRPSPSLPEPTELPLPPLLPPPPPSTTAPLPIRPPSGTKK
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
RPS6KB2
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:20 - 1:50
  • Immunohistochemistry-Paraffin 1:20 - 1:50
  • Western Blot 0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
p70 S6 Kinase beta/S6K2 Protein (NBP1-87805PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for p70 S6 Kinase beta/S6K2 Antibody

  • EC 2.7.11
  • EC 2.7.11.1
  • KLS
  • p70 ribosomal S6 kinase beta
  • p70 S6 Kinase beta
  • p70 S6KB
  • p70 S6K-beta
  • p70(S6K)-beta
  • p70-beta
  • P70-beta-1
  • P70-beta-2
  • p70-S6K 2
  • P70S6K2
  • p70S6Kb
  • ribosomal protein S6 kinase beta-2
  • ribosomal protein S6 kinase, 70kD, polypeptide 2,70 kDa ribosomal protein S6 kinase 2
  • ribosomal protein S6 kinase, 70kDa, polypeptide 2
  • RPS6KB2
  • S6K2
  • S6K-beta
  • S6K-beta2
  • S6K-beta-2
  • serine/threonine-protein kinase 14 beta
  • Serine/threonine-protein kinase 14B
  • SRK
  • STK14B
  • STK14BS6 kinase-related kinase

Background

S6K2 encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates the S6 ribosomal protein and eucaryotic translation initiation factor 4B (eIF4B). Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol RPS6KB2