p70 S6 Kinase beta/S6K2 Antibody Summary
Immunogen |
The immunogen recognized by this antibody maps to a region between residue 430 and the C-terminus (residue 482) of human Ribosomal Protein S6 Kinase, 70kda, polypeptide 2 using the numbering given in entry NP_003943.2 (GeneID 6199). |
Isotype |
IgG |
Clonality |
Polyclonal |
Host |
Rabbit |
Gene |
RPS6KB2 |
Purity |
Immunogen affinity purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Immunoprecipitation 2 -6 ug/mg of lysate
- Western Blot 1:2000-1:10000
|
Theoretical MW |
53 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Control |
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Publications |
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Packaging, Storage & Formulations
Storage |
Store at 4C. Do not freeze. |
Buffer |
TBS and 0.1% BSA |
Preservative |
0.09% Sodium Azide |
Concentration |
0.2 mg/ml |
Purity |
Immunogen affinity purified |
Alternate Names for p70 S6 Kinase beta/S6K2 Antibody
Background
This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates the S6 ribosomal protein and eucaryotic translation initiation factor 4B (eIF4B). Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Publications for p70 S6 Kinase beta/S6K2 Antibody (NB100-1545)(2)
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Product General Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
Video Protocols
FAQs for p70 S6 Kinase beta/S6K2 Antibody (NB100-1545). (Showing 1 - 1 of 1 FAQs).
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I wondered if your S6k2 antibody cross reacted with S6K1 or is it specific to S6K2 NB100-1545
- There is no mention of specifically crossreacting with any other protein but the epitope recognized by this antibody is found between aa430 and 482 of the human Ribosomal protein S6 kinase. Our lab said that there is some similarity between S6K1 and S6K2 in the sequences of the immunizing peptide. This antibody preferentially binds to S6K2 (as seen in data sheet) and it is possible under certain conditions that it would cross-react with S6K1.
Control Lysate(s)
Secondary Antibodies
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Isotype Controls
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