Home » Osteoprotegerin/TNFRSF11B » Osteoprotegerin/TNFRSF11B Antibodies » Osteoprotegerin/TNFRSF11B Antibody (98A1071) [Janelia Fluor® 635]
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Osteoprotegerin/TNFRSF11B Antibody (98A1071) [Janelia Fluor® 635]

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Product Details

Summary
Reactivity Hu, Mu, Rt, RbSpecies Glossary
Applications WB, ELISA, Flow, ICC/IF, IHC, IP, CyTOF-ready
Clone
98A1071
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 635

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB100-56505AF350
Alexa Fluor 405
NB100-56505AF405
Alexa Fluor 488
NB100-56505AF488
Alexa Fluor 532
NB100-56505AF532
Alexa Fluor 594
NB100-56505AF594
Alexa Fluor 647
NB100-56505AF647
Alexa Fluor 700
NB100-56505AF700
Alexa Fluor 750
NB100-56505AF750
Allophycocyanin
NB100-56505APC
Allophycocyanin/Cy7
NB100-56505APCCY7
Biotin
NB100-56505B
CoraFluor 1
NB100-56505CL1
DyLight 350
NB100-56505UV
DyLight 405
NB100-56505V
DyLight 488
NB100-56505G
DyLight 550
NB100-56505R
DyLight 594
NB100-56505DL594
DyLight 650
NB100-56505C
DyLight 680
NB100-56505FR
DyLight 755
NB100-56505IR
FITC
NB100-56505F
HRP
NB100-56505H
Janelia Fluor 525
NB100-56505JF525
Janelia Fluor 549
NB100-56505JF549
Janelia Fluor 585
NB100-56505JF585
Janelia Fluor 646
NB100-56505JF646
Janelia Fluor 669
NB100-56505JF669
PE
NB100-56505PE
PE/Atto594
NB100-56505PEATT594
PE/Cy5.5
NB100-56505PECY55
PE/Cy7
NB100-56505PECY7
PerCP
NB100-56505PCP
Unconjugated
NB100-56505
mFluor Violet 450 SE
NB100-56505MFV450
mFluor Violet 500 SE
NB100-56505MFV500
mFluor Violet 610 SE
NB100-56505MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NB100-56505
BSA Free
NB100-56505SS
Azide Free
NBP2-33211
BSA Free
NB100-56505
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Osteoprotegerin/TNFRSF11B Antibody (98A1071) [Janelia Fluor® 635] Summary

Immunogen
A peptide corresponding to the amino acids 20-37 TQETFPPKYLHYDEETSH of human Osteoprotegerin was used as immunogen for this antibody.
Specificity
The Osteoprotegerin antibody, clone 98A1071, detects all forms of Osteoprotegerin including monomeric, dimeric and Osteoprotegerin bound to RANKL (Vandooren, 2008) as well as Osteoprotegerin bound to TRAIL (Sandra, 2006).
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
TNFRSF11B
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • ELISA
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
  • Immunoprecipitation
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Rabbit reactivity reported in scientific literature (PMID: 31658685).

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Osteoprotegerin/TNFRSF11B Antibody (98A1071) [Janelia Fluor® 635]

  • OCIF
  • OCIFMGC29565
  • OPG
  • OPGtumor necrosis factor receptor superfamily member 11B
  • Osteoclastogenesis inhibitory factor
  • Osteoprotegerin
  • TNFRSF11B
  • TR1
  • tumor necrosis factor receptor superfamily, member 11b

Background

Osteoprotegerin is encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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PTH Antibody
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Western Blot PTH Antibody (918462) [Unconjugated]
Species: Hu
Applications: IHC, WB
IL-6 [HRP]
M6000B
N/A IL-6 [HRP]
N/A IL-6 [HRP]
N/A IL-6 [HRP]
(650 Publications)
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Dystrophin Antibody
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Immunohistochemistry-Paraffin Dystrophin Antibody
Immunohistochemistry-Paraffin Dystrophin Antibody
Immunohistochemistry-Paraffin Dystrophin Antibody
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Applications: ICC/IF, IHC, IHC-P
Bestrophin 1
Antibody (E6-6) - BSA
NB300-164
Knockout Validated Bestrophin 1 Antibody (E6-6) - BSA Free
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Immunohistochemistry-Paraffin Bestrophin 1 Antibody (E6-6) - BSA Free
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(49 Publications)
Species: Ca, Hu, Mu, Po, Pm, Rt(-)
Applications: Dual ISH-IHC, ICC/IF, IHC, IHC-Fr, IHC-P, IP, KO, PLA, WB
Osteopontin/OPN
Antibody [Unconjugate
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Immunocytochemistry Osteopontin/OPN Antibody [Unconjugated]
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(2 Reviews)
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TRAIL/TNFSF10
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TRAIL/TNFSF10 [Unconjugated]
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CD40 Ligand/TNFSF5
[HRP]
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N/A CD40 Ligand/TNFSF5 [HRP]
N/A CD40 Ligand/TNFSF5 [HRP]
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NBP1-87315
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IL-10 [Biotin]
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(299 Publications)
Species: Mu
Applications: ELISA
SLPI [HRP]
DPI00
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N/A SLPI [HRP]
(37 Publications)
Species: Hu
Applications: ELISA
RUNX2/CBFA1
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MAB2006
Immunocytochemistry RUNX2/CBFA1 Antibody (232902) [Unconjugated]
(1 Review)
(28 Publications)
Species: Hu
Applications: ICC

Osteoprotegerin/TNFRSF ...
NB100-56505JF635
Osteoprotegerin/TNFRSF11B Antibody (98A1071) [Janelia Fluor® 635]
Species: Hu, Mu, Rt, Rb
Applications: WB, ELISA, Flow, ICC/IF, IHC, IP, CyTOF-ready

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol TNFRSF11B