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NTB-A/SLAMF6/CD352 Antibody

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Immunohistochemistry-Paraffin: NTB-A/SLAMF6/CD352 Antibody [NBP2-49002] - Staining of human tonsil shows moderate positivity in germinal center and non-germinal center cells.
Immunohistochemistry-Paraffin: NTB-A/SLAMF6/CD352 Antibody [NBP2-49002] - Staining of human tonsil shows moderate positivity in germinal center and non-germinal center cells.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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NTB-A/SLAMF6/CD352 Antibody Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to amino acids: LPLEFPAGEKVNFITWLFNETSLAFIVPHETKSPEIHVTNPKQGKRLNFTQSYSLQLSNLKMEDTGSYRAQISTKT
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SLAMF6
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
NTB-A/SLAMF6/CD352 Recombinant Protein Antigen (NBP2-49002PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for NTB-A/SLAMF6/CD352 Antibody

  • Activating NK receptor
  • CD352 antigen
  • CD352
  • KALIFLJ50657
  • Ly108
  • NK-T-B-antigen
  • NTBA receptor
  • NTBA
  • NTB-A
  • NTB-AMGC104953
  • NTBAT- and B-cell antigen
  • SF2000
  • SLAM family member 6
  • SLAMF6

Background

NTBA (NK-, T-, and B-cell Antigen) is a 60 kD type I transmembrane glycoprotein. It is a member of Ig superfamily belonging to CD2/CD150 subfamily, also known as SLAMF6 (SLAM family member 6), LY108, TCOM, or SF2000. This antigen is expressed on NK cells, T cells (upregulated upon activation), and B cells. NTBA is its own ligand. The homophilic interaction of NTBA is involved in the induction of NK cytotoxicity, CD28 independent T cell costimulation, triggering Th1 cytokines production, and regulation of B cell tolerance. It may play a role in the regulation of autoimmune diseases.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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NTB-A/SLAMF6/CD352
Antibody
NBP2-49002
NTB-A/SLAMF6/CD352 Antibody
Species: Hu
Applications: IHC

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Bioinformatics

Gene Symbol SLAMF6