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NKp44/NCR2 Antibody (253415) [CoraFluor™ 1]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, CyTOF-ready, Func
Clone
253415
Clonality
Monoclonal
Host
Mouse
Conjugate
CoraFluor 1

Order Details

NKp44/NCR2 Antibody (253415) [CoraFluor™ 1] Summary

Description
CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.
Immunogen
Mouse myeloma cell line NS0-derived recombinant human NKp44/NCR2
Gln22-Pro190
Accession # CAB52289
Specificity
Detects human NKp44/NCR2 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) NKp30, rhNKp46, rhNKp80, or recombinant mouse NKp46 is observed.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
NCR2
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Agonist Activity
  • CyTOF-reported
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
No Preservative
Purity
Protein A or G purified

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for NKp44/NCR2 Antibody (253415) [CoraFluor™ 1]

  • CD336 antigen
  • CD336
  • LY95
  • LY95lymphocyte antigen 95 homolog (activating NK-receptor; NK-p44)
  • lymphocyte antigen 95 (activating NK-receptor; NK-p44)
  • Lymphocyte antigen 95 homolog
  • natural cytotoxicity triggering receptor 2
  • Natural killer cell p44-related protein
  • NCR2
  • NK cell activating receptor (NKp44)
  • NK cell-activating receptor
  • NKp44
  • NK-p44dJ149M18.1

Background

NKp44 (NCR2) is a member of the natural cytotoxicity receptor (NCR) family that is expressed on activated human NK cells. NKp44 displays a single extracellular Ig-like V domain and a transmembrane portion containing the charged residue (Lysine), likely involved in the association with KARAP/DAP12 molecules. Gene coding for NKp44 maps on human chromosome 6p21.1.This antibody is specific for NKp44 and does not cross react with NKp30 and NKp46.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol NCR2