NKG2E/KLRC3 Antibody (3D5)

This product is produced by and distributed for Abnova, a company based in Taiwan.

Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. KLRC3 is a member of the NKG2 group which are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. Alternative splicing results in multiple transcript variants encoding different isoforms.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Showing Publications 1 - 2 of 2.

Publications using H00003823-M01	Applications	Species
Orbelyan GA, Tang F, Sally B et al. Human NKG2E Is Expressed and Forms an Intracytoplasmic Complex with CD94 and DAP12. J Immunol. 2014-06-16 [PMID: 24935923]
Cheray M, Petit D, Forestier L et al. Glycosylation-related gene expression is linked to differentiation status in glioblastomas undifferentiated cells. Cancer Lett 2011-09-09 [PMID: 21899947]

Array H00003823-M01

• NKG2E/KLRC3 Antibodies
• NKG2E/KLRC3 Lysate
• NKG2E/KLRC3 Proteins
• NKG2E/KLRC3 Proteins and Enzyme