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NKG2A/CD159a/KLRC1 Antibody (131411) [Phycoerythrin]

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Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human NCAM-1/CD56 APC-conjugated Monoclonal Antibody (Catalog # FAB2408A) and either (A) Mouse Anti-Human NKG2A/CD159a PE-conjugated ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
131411
Clonality
Monoclonal
Host
Mouse
Conjugate
Phycoerythrin

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NKG2A/CD159a/KLRC1 Antibody (131411) [Phycoerythrin] Summary

Immunogen
BaF3 mouse pro-B cell line transfected with human NKG2A and CD94
Specificity
Recognizes the human NKG2A/CD94 heterodimer. It does not recognize the NKG2C/CD94 heterodimer or the CD94 homodimer.
Source
N/A
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
KLRC1
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 10 uL/10^6 cells
Reviewed Applications
Read 2 Reviews rated 4
using
FAB1059P in the following application:

Publications
Read Publications using
FAB1059P in the following applications:

Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for NKG2A/CD159a/KLRC1 Antibody (131411) [Phycoerythrin]

  • CD159 antigen-like family member A
  • CD159a antigen
  • CD159a
  • C-lectin type II protein
  • killer cell lectin-like receptor subfamily C, member 1
  • Klrc1
  • MGC13374
  • natural killer cell lectin
  • natural killer group protein 2
  • NK cell receptor A
  • NKG2
  • NKG2-1/B activating NK receptor
  • NKG2A
  • NKG2-A
  • NKG2-A/B type II integral membrane protein
  • NKG2-A/B-activating NK receptor
  • NKG2-A/NKG2-B type II integral membrane protein
  • NKG2AMGC59791
  • NKG2-B

Background

NKG2A, also known as CD159a, is a type II transmembrane receptor having a single extracellular lectin-like domain and a cytoplasmic ITIM motif. It associates with CD94 and is expressed on NK cells and some activated T cell populations. The NKG2A/CD94 complex delivers an inhibitory signal upon recognition of its ligand, HLA-E.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for NKG2A/CD159a/KLRC1 Antibody (FAB1059P)(39)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 2 applications: FLOW, Flow Cytometry.


Filter By Application
FLOW
(1)
Flow Cytometry
(31)
All Applications
Filter By Species
Human
(32)
All Species
Showing Publications 1 - 10 of 39. Show All 39 Publications.
Publications using FAB1059P Applications Species
Rubino, V;Carriero, F;Palatucci, AT;Giovazzino, A;Leone, S;Nicolella, V;Calabrò, M;Montanaro, R;Brancaleone, V;Pane, F;Chiurazzi, F;Ruggiero, G;Terrazzano, G; Adaptive and Innate Cytotoxic Effectors in Chronic Lymphocytic Leukaemia (CLL) Subjects with Stable Disease International journal of molecular sciences 2023-05-31 [PMID: 37298547] (Flow Cytometry, Human) Flow Cytometry Human
Thi-Anh-Thuy Tran, Young-Hee Kim, Thi-Hoang-Oanh Duong, JayaLakshmi Thangaraj, Tan-Huy Chu, Shin Jung et al. Natural killer cell therapy potentially enhances the antitumor effects of bevacizumab plus irinotecan in a glioblastoma mouse model Frontiers in Immunology 2023-01-10 [PMID: 36703992]
Marisa Market, Gayashan Tennakoon, Marlena Scaffidi, David P. Cook, Leonard Angka, Juliana Ng et al. Preventing Surgery-Induced NK Cell Dysfunction Using Anti-TGF-beta Immunotherapeutics International Journal of Molecular Sciences 11/23/2022 [PMID: 36498937]
A Teramo, A Binatti, E Ciabatti, G Schiavoni, G Tarrini, G Barilà, G Calabretto, C Vicenzetto, VR Gasparini, M Facco, I Petrini, R Grossi, N Pisanti, S Bortoluzzi, B Falini, E Tiacci, S Galimberti, G Semenzato, R Zambello Defining TCRgammadelta lymphoproliferative disorders by combined immunophenotypic and molecular evaluation Nature Communications, 2022-06-08;13(1):3298. 2022-06-08 [PMID: 35676278] (Flow Cytometry, Human) Flow Cytometry Human
Z Wang, HP McWilliams, H Reza, JR Ostberg, W Chen, X Wang, C Huynh, V Vyas, WC Chang, R Starr, JR Wagner, B Aguilar, X Yang, X Wu, J Wang, W Chen, E Koelker-Wo, CS Seet, A Montel-Hag, GM Crooks, SJ Forman, CE Brown 3D-organoid culture supports differentiation of human CAR+ iPSCs into highly functional CAR T�cells Cell Stem Cell, 2022-03-11;0(0):. 2022-03-11 [PMID: 35278370] (Flow Cytometry, Human) Flow Cytometry Human
Charly R. Good, M. Angela Aznar, Shunichiro Kuramitsu, Parisa Samareh, Sangya Agarwal, Greg Donahue et al. An NK-like CAR T cell transition in CAR T cell dysfunction Cell 2021-12-02 [PMID: 34861191]
MA Streltsova, MO Ustiuzhani, EV Barsov, SA Kust, RA Velichinsk, EI Kovalenko Telomerase Reverse Transcriptase Increases Proliferation and Lifespan of Human NK Cells without Immortalization Biomedicines, 2021-06-09;9(6):. 2021-06-09 [PMID: 34207853] (Flow Cytometry, Human) Flow Cytometry Human
JH Ruth, M Gurrea-Rub, KS Athukorala, SM Rasmussen, D Weber, PM Randon, RJ Gedert, ME Lind, MA Amin, PL Campbell, PS Tsou, Y Mao-Draaye, Q Wu, TM Lanigan, VG Keshamouni, NG Singer, F Lin, DA Fox CD6 is a target for cancer immunotherapy JCI Insight, 2021-03-08;0(0):. 2021-03-08 [PMID: 33497367] (Flow Cytometry, Human) Flow Cytometry Human
TN Dao, S Utturkar, N Atallah La, S Matosevic TIM-3 Expression Is Downregulated on Human NK Cells in Response to Cancer Targets in Synergy with Activation Cancers (Basel), 2020-08-26;12(9):. 2020-08-26 [PMID: 32858904] (Flow Cytometry, Human) Flow Cytometry Human
Marisa Market, Gayashan Tennakoon, Juliana Ng, Marlena Scaffidi, Christiano Tanese de Souza, Michael A. Kennedy et al. A Method of Assessment of Human Natural Killer Cell Phenotype and Function in Whole Blood Frontiers in Immunology 5/20/2020 [PMID: 32508837]
Show All 39 Publications.

Reviews for NKG2A/CD159a/KLRC1 Antibody (FAB1059P) (2) 42

Average Rating: 4
(Based on 2 reviews)
We have 2 reviews tested in 1 species: Human.

Reviews using FAB1059P:
Filter by Applications
Flow
(2)
All Applications
Filter by Species
Human
(2)
All Species
Images Ratings Applications Species Date Details
  4
reviewed by:
Verified Customer
Flow Human 01/21/2015
View

Summary

ApplicationFlow Cytometry
Sample TestedSee PMID: 20167234
SpeciesHuman
  4
reviewed by:
Verified Customer
Flow Human 01/21/2015
View

Summary

ApplicationFlow Cytometry
Sample TestedSee PMID: 20167234
SpeciesHuman

Product General Protocols

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FAQs for NKG2A/CD159a/KLRC1 Antibody (FAB1059P) (0)

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Secondary Antibodies

 

Isotype Controls

Additional NKG2A/CD159a/KLRC1 Products

Blogs on NKG2A/CD159a/KLRC1.

Harnessing Natural Killer Cell Activity for Anti-Tumor Immunotherapy
By Victoria Osinski, PhDWhat’s “Natural” About Natural Killer (NK) Cells?For immunologists, the term cytotoxicity often conjures up images of an army of antigen specific CD8+ T cells deploying to ...  Read full blog post.

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Recent Reviews

4
5
0
4
2
3
0
2
0
1
0

 
Verified Customer
01/21/2015
Application: Flow
Species: Human

 
Verified Customer
01/21/2015
Application: Flow
Species: Human

Bioinformatics

Gene Symbol KLRC1