NG2/MCSP Antibody (LHM 2)

NG2 (Neuron Glial Antigen 2), also known as MCSP, and CSPG4 is a chondroitin surface proteoglycan. Chondroitin surface proteoglycans play a role in stabilizing cell-substratum interactions during early events of cell spreading. At large, proteoglycans are important for cell proliferation and migration, and may act as signal transducers through C-terminal cytoplasmic binding to scaffolding or signaling proteins. The NG2 glycoprotein is a type I membrane protein expressed in the developing and adult central nervous system (CNS) by subpopulations of glia including oligodendroglial precursor cells (OPCs), and in the developing CNS additionally by pericytes. NG2 is located at the apical cell membrane, however it has also been shown to localize to the lamellipodia of astrocytoma upon phosphorylation by PRKCA. Research has found that NG2 may inhibit neuronal growth (PMC1571583), and also acts as a proapoptotic receptor.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 4 applications: ICC/IF, IF/IHC, IHC-P, WB.

Showing Publications 1 - 10 of 13. Show All 13 Publications. Collapse Publications.

Publications using NB100-2688	Applications	Species
Koivunotko E, Snirvi J, Merivaara A Et al. Angiogenic Potential of Human Adipose-Derived Mesenchymal Stromal Cells in Nanofibrillated Cellulose Hydrogel Biomedicines 2022-10-27 [PMID: 36289846] (WB, Human) Details: Citation using the Azide and BSA Free version of this antibody.	WB	Human
Lin Z, Zhang X, Fritch MR Et al. Engineering pre-vascularized bone-like tissue from human mesenchymal stem cells through simulating endochondral ossification Biomaterials 2022-03-08 [PMID: 35259584] (IHC-P, Human) Details: Citation using the Alexa Fluor 594 version of this antibody.	IHC-P	Human
Liu HY, Koch C, Haller A Et al. Evaluation of Microfluidic Ceiling Designs for the Capture of Circulating Tumor Cells on a Microarray Platform Adv Biosyst 2020-04-16 [PMID: 32293134] Details: Citation using the PE version of this antibody.
Arrigoni C, Bongio M, Talo G et al. Rational Design of Prevascularized Large 3D Tissue Constructs Using Computational Simulations and Biofabrication of Geometrically Controlled Microvessels. Adv Healthc Mater. 2016-05-18 [PMID: 27191352] (ICC/IF, Human)	ICC/IF	Human
Stoyanov D The Role of Transcription Factor ZBTB20 in the Development of Interneurons in the Neocortex of Mice Thesis 2023-01-01
Dey D, Tyagi S, Shrivastava V et al. Using human fetal neural stem cells to elucidate the role of the JAK-STAT cell signaling pathway in oligodendrocyte differentiation in vitro Research Square 2023-11-01 [PMID: 38227271] (ICC/IF, Human)	ICC/IF	Human
Monica Nanni, Dominic Rütsche, Curdin Bächler, Luca Pontiggia, Agnes S. Klar, Ueli Moehrlen, Thomas Biedermann CD146 expression profile in human skin and pre-vascularized dermo-epidermal skin substitutes in vivo Journal of Biological Engineering 2023-01-31 [PMID: 36721239]
Li X, Guo W, Zha K et al. Enrichment of CD146+ Adipose-Derived Stem Cells in Combination with Articular Cartilage Extracellular Matrix Scaffold Promotes Cartilage Regeneration Theranostics 2019-07-09 [PMID: 31410204] (WB, Human)	WB	Human
Kinney HC, Haynes RL, Xu G, Andiman SE, Folkerth RD, Sleeper LA, Volpe JJ. Neuron deficit in the white matter and subplate in periventricular leukomalacia. Ann Neurol;71(3):397-406. 2012-03-01 [PMID: 22451205] (IF/IHC, ICC/IF, Human)	IF/IHC, ICC/IF	Human
Pierce GL, Donato AJ, LaRocca TJ, Eskurza I, Silver AE, Seals DR. Habitually exercising older men do not demonstrate age-associated vascular endothelial oxidative stress. Aging Cell;10(6):1032-7. 2011-12-01 [PMID: 21943306] (ICC/IF, Human)	ICC/IF	Human
Wang Y-C, Nakagawa M, Garitaonandia I et al. Specific lectin biomarkers for isolation of human pluripotent stem cells identified through array-based glycomic analysis. Cell Research. 2011-09-06 [PMID: 21894191]
Kose O, Kutulola AO, Odell EW, Waseem A. Changes in the expression of stem cell markers in oral lichen planus and hyperkeratotic lesions. J Oral Sci. 2007-06-01 [PMID: 17634726] (IF/IHC, Human)	IF/IHC	Human
Legg J, Jensen UB, Broad S et al. Role of melanoma chondroitin sulphate proteoglycan in patterning stem cells in human interfollicular epidermis. Development. 2003-12-01 [PMID: 14573520] (ICC/IF, Human)	ICC/IF	Human
Show All 13 Publications. Collapse Publications.

Array NB100-2688

• NG2/MCSP Antibodies
• NG2/MCSP ELISA Kits
• NG2/MCSP Proteins
• NG2/MCSP Proteins and Enzyme