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NFkB1/NFkB p105 Antibody [CoraFluor™ 1]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
CoraFluor 1

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP3-05867AF350
Alexa Fluor 405
NBP3-05867AF405
Alexa Fluor 488
NBP3-05867AF488
Alexa Fluor 532
NBP3-05867AF532
Alexa Fluor 594
NBP3-05867AF594
Alexa Fluor 647
NBP3-05867AF647
Alexa Fluor 700
NBP3-05867AF700
Alexa Fluor 750
NBP3-05867AF750
Allophycocyanin
NBP3-05867APC
Biotin
NBP3-05867B
DyLight 350
NBP3-05867UV
DyLight 405
NBP3-05867V
DyLight 488
NBP3-05867G
DyLight 550
NBP3-05867R
DyLight 594
NBP3-05867DL594
DyLight 650
NBP3-05867C
DyLight 680
NBP3-05867FR
DyLight 755
NBP3-05867IR
FITC
NBP3-05867F
HRP
NBP3-05867H
Janelia Fluor 525
NBP3-05867JF525
Janelia Fluor 549
NBP3-05867JF549
Janelia Fluor 585
NBP3-05867JF585
Janelia Fluor 635
NBP3-05867JF635
Janelia Fluor 646
NBP3-05867JF646
Janelia Fluor 669
NBP3-05867JF669
PE
NBP3-05867PE
PerCP
NBP3-05867PCP
Unconjugated
NBP3-05867-100ul
mFluor Violet 450 SE
NBP3-05867MFV450
mFluor Violet 500 SE
NBP3-05867MFV500
mFluor Violet 610 SE
NBP3-05867MFV610
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NFkB1/NFkB p105 Antibody [CoraFluor™ 1] Summary

Description
CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.
Immunogen
Produced in rabbits immunized with a synthetic peptide corresponding to the N-terminus of the Human NFkB1/NFkB p105.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
NFKB1
Purity
Antigen and protein A Affinity-purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
No Preservative
Purity
Antigen and protein A Affinity-purified

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for NFkB1/NFkB p105 Antibody [CoraFluor™ 1]

  • DNA-binding factor KBF1
  • EBP-1
  • NF-kappa-B
  • NFkB1
  • NF-kB1
  • NFKB-p105
  • Nuclear factor NF-kappa-B p105 subunit
  • Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
  • p105

Background

Nuclear factor kappa beta (NFKB) is a transcription factor that is highly influenced by stress, free-radicals, UV light and hypoxia. Unsurprisingly, NFKB is essential for many human cancers, as it regulates the expression of many downstream proteins that regulate or modify cellular growth and development. NFKB effects on angiogenic pathways and reactive mechanisms to stress and damage are well established throughout literature. Atherosclerosis is partly attributed to the mis-regulation of NFKB in hypoxia. Arthritis is related to inflammation proteins regulated through NFKB. It also has been shown to be important in synapses in brain, leading to memory and cognitive ability or impairment. In all, NFKB is one of the fastest responding transcription factors in humans, and is likely to mediate many responsive events in diseases and injury recovery.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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NFkB1/NFkB p105 Antibody [CoraFluor™ 1]
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Bioinformatics

Gene Symbol NFKB1