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Myoferlin Antibody [DyLight 550]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
DyLight 550

Order Details

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Myoferlin Antibody [DyLight 550] Summary

Immunogen
The immunogen this antibody was made to, maps to a region between residue 700 to 750 of human Myoferlin using the numbering given in entry NP_038479.1 (GeneID 26509).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
MYOF
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunoprecipitation
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Myoferlin Antibody [DyLight 550]

  • fer-1 (C.elegans)-like 3 (myoferlin)
  • FER1L3
  • fer-1-like 3, myoferlin (C. elegans)
  • fer-1-like 3, myoferlin
  • Fer-1-like protein 3
  • FLJ36571
  • FLJ90777
  • KIAA1207
  • myoferlin

Background

Myoferlin belongs to the ferlin family and contains five C2 domains. It is a calcium/phospholipid binding protein that plays a role in the plasmalemma repair mechanism of endothelial cells that permits rapid resealing of membranes disrupted by mechanical stress. It is also involved in endocytic recycling and implicated in VEGF signal transduction by regulating the levels of the receptor KDR. Myoferlin is expressed in myoblast and endothelial cells (at protein level), highly expressed in cardiac and skeletal muscles, also present in lung and at very low levels in kidney, placenta and brain. There are eight named isoforms.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol MYOF