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Myocilin Antibody (2B4)

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Western Blot: Myocilin Antibody (2B4) [H00004653-M02] - Analysis of MYOC expression in transfected 293T cell line by MYOC monoclonal antibody (M02), clone 2B4.Lane 1: MYOC transfected lysate(57 KDa).Lane 2: Non-transfected lysate.
Western Blot: Myocilin Antibody (2B4) [H00004653-M02] - Analysis of MYOC expression in transfected 293T cell line by MYOC monoclonal antibody (M02), clone 2B4.Lane 1: MYOC transfected lysate(57 KDa).Lane 2: ...read more
Sandwich ELISA: Myocilin Antibody (2B4) [H00004653-M02] - Detection limit for recombinant GST tagged MYOC is approximately 0.3ng/ml as a capture antibody.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clone
2B4
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

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Myocilin Antibody (2B4) Summary

Description
Quality control test: Antibody Reactive Against Recombinant Protein.
Immunogen
MYOC (AAH29261, 1 a.a. ~ 504 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MRFFCARCCSFGPEMPAVQLLLLACLVWDVGARTAQLRKANDQSGRCQYTFSVASPNESSCPEQSQAMSVIHNLQRDSSTQRLDLEATKARLSSLESLLHQLTLDQAARPQETQEGLQRELGTLRRERDQLETQTRELETAYSNLLRDKSVLEEEKKRLRQENENLARRLESSSQEVARLRRGQCPQTRDTARAVPPGSREVSTWNLDTLAFQELKSELTEVPASRILKESPSGYLRSGEGDTGCGELVWVGEPLTLRTAETITGKYGVWMRDPKPTYPYTQETTWRIDTVGTDVRQVFEYDLISQFMQGYPSKVHILPRPLESTGAVVYSGSLYFQGAESRTVIRYELNTETVKAEKEIPGAGYHGQFPYSWGGYTDIDLAVDEAGLWVIYSTDEAKGAIVLSKLNPENLELEQTWETNIRKQSVANAFIICGTLYTVSSYTSADATVNFAYDTGTGISKTLTIPFKNRYKYSSMIDYNPLEKKLFAWDNLNMVTYDIKLSKM
Specificity
MYOC - myocilin, trabecular meshwork inducible glucocorticoid response (2B4)
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
MYOC
Purity
IgG purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Sandwich ELISA
  • Western Blot 1:500
Application Notes
Antibody reactivity against transfected lysate and recombinant protein for WB. It has been used for ELISA.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
In 1x PBS, pH 7.4
Preservative
No Preservative
Purity
IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Myocilin Antibody (2B4)

  • GLC1A
  • GLC1Amyocilin
  • GPOA
  • JOAG
  • JOAG1
  • MYOC
  • Myocilin
  • myocilin, trabecular meshwork inducible glucocorticoid response
  • TIGR
  • TIGRmutated trabecular meshwork-induced glucocorticoid response protein
  • Trabecular meshwork-induced glucocorticoid response protein

Background

MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol MYOC
Entrez
Uniprot