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Myelin PLP Antibody - BSA Free

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Orthogonal Strategies: Immunohistochemistry-Paraffin: Myelin PLP Antibody [NBP1-87781] - Staining in human cerebral cortex and pancreas tissues using anti-PLP1 antibody. Corresponding PLP1 RNA-seq data are ...read more
Immunohistochemistry-Paraffin: Myelin PLP Antibody [NBP1-87781] - Border of a demyelinated lesion. Image submitted by a verified customer review.
Immunohistochemistry-Paraffin: Myelin PLP Antibody [NBP1-87781] - Staining of human cerebral cortex shows high expression.
Immunohistochemistry-Paraffin: Myelin PLP Antibody [NBP1-87781] - Staining of human pancreas shows low expression as expected.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free
Validated by:
       

Orthogonal Strategies

 

Order Details

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Catalog# & Formulation Size Price

Myelin PLP Antibody - BSA Free Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: LLLAEGFYTTGAVRQIFGDYKTTICGKGLSATVTGGQKGRGSRGQHQAHSLERVCHCLGKWLGHPDKFVGI
Marker
Oligodendrocyte Marker
Predicted Species
Rat (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PLP1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:500 - 1:1000
  • Immunohistochemistry-Paraffin 1:500 - 1:1000
  • Western Blot Reactivity reported in literature (PMID: 26209807)
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
Myelin PLP Protein (NBP1-87781PEP)
Reviewed Applications
Read 1 Review rated 5
using
NBP1-87781 in the following applications:

Publications
Read Publications using
NBP1-87781 in the following applications:

Reactivity Notes

Mouse reactivity reported in scientific literature (PMID: 26209807).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Myelin PLP Antibody - BSA Free

  • DM-20
  • HLD1
  • Lipophilin
  • major myelin proteolipid protein
  • MMPL
  • Myelin PLP
  • myelin proteolipid protein
  • PLP
  • PLP/DM20
  • PLP1
  • PMD
  • proteolipid protein 1
  • spastic paraplegia 2, uncomplicated
  • SPG2

Background

Human PLP (also known as lipophilin) is a 30 kDa protein (277 amino acids) found in myelin of the CNS and PNS. Expressed by oligodendrocytes and Schwann cells, PLP stabilizes myelin by preventing lipid bilayer fusion, and aids in compaction. Different mutations of the human PLP gene product result in two neurological disorders - Pelizaeus-Merzbacher disease and Spastic Paraplegia type 2.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Myelin PLP Antibody (NBP1-87781)(6)

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 5 applications: Block/Neutralize, ICC/IF, Immunocytochemistry/ Immunofluorescence, WB, Western Blot.


Filter By Application
Block/Neutralize
(1)
ICC/IF
(1)
Immunocytochemistry/ Immunofluorescence
(1)
WB
(1)
Western Blot
(1)
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Human
(1)
Mouse
(1)
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Showing Publications 1 - 6 of 6.
Publications using NBP1-87781 Applications Species
Cifuentes-Diaz C, Canali G, Garcia M et al. Differential impacts of Cntnap2 heterozygosity and Cntnap2 null homozygosity on axon and myelinated fiber development in mouse Frontiers in Neuroscience 2023-01-30 [PMID: 36793543] (Western Blot, Block/Neutralize) Western Blot, Block/Neutralize
Kornelius E, Tsou SH, Chang CC et al. Liraglutide Attenuates Glucolipotoxicity-Induced RSC96 Schwann Cells' Inflammation and Dysfunction Biomolecules 2022-09-21 [PMID: 36291547] (Immunocytochemistry/ Immunofluorescence) Immunocytochemistry/ Immunofluorescence
Gomez-Pinedo U, MatIas-Guiu JA, Torre-Fuentes L et al. Variant rs4149584 (R92Q) of the TNFRSF1A gene in patients with familial multiple sclerosis Neurologia (Barcelona, Spain) 2022-08-10 [PMID: 35963536] (ICC/IF, Human) ICC/IF Human
Creighton BA, Afriyie S, Ajit D Et al. Giant ankyrin-B mediates transduction of axon guidance and collateral branch pruning factor sema 3A eLife 2021-11-23 [PMID: 34812142]
M Horiuchi, Y Suzuki-Hor, T Akiyama, A Itoh, D Pleasure, E Carstens, T Itoh Differing intrinsic biological properties between forebrain and spinal oligodendroglial lineage cells J. Neurochem., 2017-06-09;0(0):. 2017-06-09 [PMID: 28512742]
Li Q, Tsuneki M, Krauthammer M et al. Modulation of Sox10, HIF-1a, Survivin, and YAP by Minocycline in the Treatment of Neurodevelopmental Handicaps following Hypoxic Insult. Am. J. Pathol. 2015-07-22 [PMID: 26209807] (WB, Mouse) WB Mouse

Review for Myelin PLP Antibody (NBP1-87781) (1) 51

Average Rating: 5
(Based on 1 review)
We have 1 review tested in 1 species: Other.

Reviews using NBP1-87781:
Filter by Applications
IHC-P
(1)
All Applications
Filter by Species
Other
(1)
All Species
Images Ratings Applications Species Date Details
Immunohistochemistry-Paraffin Myelin PLP NBP1-87781
Enlarge
5
reviewed by:
Verified Customer
IHC-P Other 04/25/2014
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Summary

ApplicationImmunohistochemistry-Paraffin
SpeciesOther

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for Myelin PLP Antibody (NBP1-87781) (0)

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Secondary Antibodies

 

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Recent Reviews

5
5
1
4
0
3
0
2
0
1
0

Verified Customer
04/25/2014
Application: IHC-P
Species: Other

Bioinformatics

Gene Symbol PLP1