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Myelin PLP Antibody

Images

 
Orthogonal Strategies: Immunohistochemistry-Paraffin: Myelin PLP Antibody [NBP1-87781] - Staining in human cerebral cortex and pancreas tissues using anti-PLP1 antibody. Corresponding PLP1 RNA-seq data are ...read more
Immunohistochemistry-Paraffin: Myelin PLP Antibody [NBP1-87781] - Border of a demyelinated lesion. Image submitted by a verified customer review.
Immunohistochemistry-Paraffin: Myelin PLP Antibody [NBP1-87781] - Staining of human cerebral cortex shows high expression.
Immunohistochemistry-Paraffin: Myelin PLP Antibody [NBP1-87781] - Staining of human pancreas shows low expression as expected.
Loss of AnkB440 does not change levels of myelination of CC axons. (H) Western blot analysis of the expression of AnkB isoforms and multiple proteins (MBP, myelin-PLP, CNPase, MAG, MOG) associated with myelination in ...read more

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
       

Orthogonal Strategies

 

Order Details

Myelin PLP Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: LLLAEGFYTTGAVRQIFGDYKTTICGKGLSATVTGGQKGRGSRGQHQAHSLERVCHCLGKWLGHPDKFVGI
Marker
Oligodendrocyte Marker
Predicted Species
Rat (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PLP1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:500 - 1:1000
  • Immunohistochemistry-Paraffin 1:500 - 1:1000
  • Western Blot Reactivity reported in literature (PMID: 26209807)
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
Myelin PLP Protein (NBP1-87781PEP)
Reviewed Applications
Read 1 Review rated 5
using
NBP1-87781 in the following applications:

Publications
Read Publications using
NBP1-87781 in the following applications:

  • B/N
    1 publication
  • 2 publications
  • WB
    2 publications

Reactivity Notes

Mouse reactivity reported in scientific literature (PMID: 26209807).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Myelin PLP Antibody

  • DM-20
  • HLD1
  • Lipophilin
  • major myelin proteolipid protein
  • MMPL
  • Myelin PLP
  • myelin proteolipid protein
  • PLP
  • PLP/DM20
  • PLP1
  • PMD
  • proteolipid protein 1
  • spastic paraplegia 2, uncomplicated
  • SPG2

Background

Human PLP (also known as lipophilin) is a 30 kDa protein (277 amino acids) found in myelin of the CNS and PNS. Expressed by oligodendrocytes and Schwann cells, PLP stabilizes myelin by preventing lipid bilayer fusion, and aids in compaction. Different mutations of the human PLP gene product result in two neurological disorders - Pelizaeus-Merzbacher disease and Spastic Paraplegia type 2.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Myelin PLP Antibody (NBP1-87781)(5)

Review for Myelin PLP Antibody (NBP1-87781) (1) 51

Average Rating: 5
(Based on 1 review)
We have 1 review tested in 1 species: Other.

Reviews using NBP1-87781:
Filter by Applications
IHC-P
(1)
All Applications
Filter by Species
Other
(1)
All Species
Images Ratings Applications Species Date Details
Immunohistochemistry-Paraffin Myelin PLP NBP1-87781
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5
reviewed by:
Verified Customer
IHC-P Other 04/25/2014
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Summary

ApplicationImmunohistochemistry-Paraffin
SpeciesOther

Product General Protocols

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Video Protocols

WB Video Protocol

FAQs for Myelin PLP Antibody (NBP1-87781) (0)

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Secondary Antibodies

 

Isotype Controls

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Blogs on Myelin PLP

There are no specific blogs for Myelin PLP, but you can read our latest blog posts.
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Contact Information

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Calculators

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Recent Reviews

5
5
1
4
0
3
0
2
0
1
0

Verified Customer
04/25/2014
Application: IHC-P
Species: Other

Bioinformatics

Gene Symbol PLP1