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MUCDHL Antibody

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Mouse kidney single‑cell suspension was stained with Goat Anti-Mouse MUCDHL Antigen Affinity-purified Polyclonal Antibody (Catalog # AF4159, filled histogram) or isotype control antibody (Catalog # AB-108-C, open ...read more

Product Details

Summary
Reactivity MuSpecies Glossary
Applications WB, Flow, CyTOF-ready
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
LYOPH

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Catalog# & Formulation Size Price
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MUCDHL Antibody Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse MUCDHL
Gln29-Ala479
Accession # NP_082345
Specificity
Detects mouse MUCDHL in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 5% cross-reactivity with recombinant human MUCDHL is observed.
Source
N/A
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
CDHR5
Purity Statement
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry 2.5 ug/10^6 cells
  • Western Blot 0.1 ug/mL

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for MUCDHL Antibody

  • cadherin-related family member 5
  • CDHR5
  • FLJ20219
  • MUCDHL
  • MUCDHLmucin-like protocadherin
  • Mucin and cadherin-like protein
  • mucin and cadherin-like
  • MUPCDH
  • MU-PCDH
  • mu-protocadherin

Background

Mucin and cadherin-like protein (MUCDHL), also known as μ-protocadherin, is a 100 kDa type I transmembrane protein belonging to the protocadherin family of cell adhesion molecules. It is found apically on the brush border of renal proximal tubule epithelial cells. The extracellular domain of mature mouse MUCDHL contains four cadherin domains plus three repeat regions that constitute a mucin stalk (aa 541‑614). At least one splice variant exists in mouse that shows a deletion of aa’s 459‑620. Over aa’s 29‑479, mouse MUCDHL shares 63% and 79% aa identity with human and rat MUCDHL, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol CDHR5
Uniprot