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mtTFA Antibody (18G102B2E11) [DyLight 550]

 
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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, Simple Western, ICC/IF, IHC, KD, KO
Clone
18G102B2E11
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 550

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP1-71648AF350
Alexa Fluor 405
NBP1-71648AF405
Alexa Fluor 488
NBP1-71648AF488
Alexa Fluor 532
NBP1-71648AF532
Alexa Fluor 594
NBP1-71648AF594
Alexa Fluor 647
NBP1-71648AF647
Alexa Fluor 700
NBP1-71648AF700
Alexa Fluor 750
NBP1-71648AF750
Biotin
NBP1-71648B
DyLight 350
NBP1-71648UV
DyLight 405
NBP1-71648V
DyLight 488
NBP1-71648G
DyLight 594
NBP1-71648DL594
DyLight 650
NBP1-71648C
DyLight 680
NBP1-71648FR
DyLight 755
NBP1-71648IR
FITC
NBP1-71648F
HRP
NBP1-71648H
Janelia Fluor 549
NBP1-71648JF549
Janelia Fluor 646
NBP1-71648JF646
Unconjugated
NBP1-71648
mFluor Violet 450 SE
NBP1-71648MFV450
mFluor Violet 500 SE
NBP1-71648MFV500
mFluor Violet 610 SE
NBP1-71648MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP1-71648
Azide and BSA Free
NBP2-80858
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mtTFA Antibody (18G102B2E11) [DyLight 550] Summary

Immunogen
Human mtTFA [Swiss-Prot# Q00059]
Localization
Mitochondrion.
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
TFAM
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Knockdown Validated
  • Knockout Validated
  • Simple Western
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Mouse reactivity reported in scientific literature (PMID: 28053692)

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for mtTFA Antibody (18G102B2E11) [DyLight 550]

  • mitochondrial transcription factor A
  • MtTF1
  • mtTFA
  • TCF-6
  • TCF6L1
  • TCF6L2Mitochondrial transcription factor 1
  • TCF6TCF6L3
  • Transcription factor 6
  • Transcription factor 6-like 2 (mitochondrial transcription factor)
  • Transcription factor 6-like 2
  • transcription factor A, mitochondrial

Background

Mitochondrial transcription factor A (mtTFA) is one of the most important transcription factors related to mitochondrial genes. In turn, mtTFA regulates several pathways for metabolism and energy storage in cells. In several metabolic diseases, including insulin-resistance related diabetes, the activity of mtTFA is directly linked to interactions with oxidative stress and fat cell differentiation. In cancers, mtTFA is important in supporting the energy requirements of the fast-growing cells. When dysfunctions in mitochondrial activity occur, mtTFA and its relationship to other proteins is often to blame; mtTFA is known to interact with TNF-alpha, PPAR, UCP4, POLRMT and others. Increased expression of mtTFA might be a good biomarker for Arsenic-induced Bowen's disease.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Species: Hu, Mu, Rt
Applications: WB, Simple Western, ICC/IF, IHC, KD, KO

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Bioinformatics

Gene Symbol TFAM