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Mouse Pentraxin 3/TSG-14 Quantikine ELISA Kit

 (5 Publications)
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Summary
Reactivity MuSpecies Glossary
Applications ELISA
Conjugate
HRP

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Mouse Pentraxin 3/TSG-14 Quantikine ELISA Kit Summary

Background
The Quantikine Mouse Pentraxin 3 Immunoassay is a 4.5 hour solid-phase ELISA designed to measure mouse PTX3 in cell culture supernates, serum, and plasma. It contains NS0-expressed recombinant mouse PTX3 and antibodies raised against the recombinant factor. This immunoassay has been shown to accurately quantitate the recombinant factor. Results obtained using natural mouse PTX3 showed linear... curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for naturally occurring mouse PTX3.
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Specificity
Natural and recombinant mouse PTX3
Source
N/A
Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
Ptx3

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using MPTX30.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mouse Pentraxin 3/TSG-14 Quantikine ELISA Kit

  • alpha-induced protein 5
  • pentaxin-related gene, rapidly induced by IL-1 beta, tumor necrosis factor
  • Pentaxin-related protein PTX3
  • Pentraxin 3
  • pentraxin 3, long
  • pentraxin-3
  • pentraxin-related gene, rapidly induced by IL-1 beta
  • pentraxin-related protein PTX3
  • PTX3
  • TNF alpha-induced protein 5
  • TNFAIP5
  • TSG14
  • TSG-14
  • TSG-14pentaxin-related gene, rapidly induced by IL-1 beta
  • Tumor necrosis factor alpha-induced protein 5
  • tumor necrosis factor, alpha-induced protein 5
  • Tumor necrosis factor-inducible gene 14 protein
  • tumor necrosis factor-inducible protein TSG-14

Background

Pentraxin 3 (PTX3), also known as TNF-stimulated gene 14 (TSG-14), is a secreted glycoprotein belonging to the Pentraxin family of proteins. It is the prototypical long Pentraxin, exhibiting a C-terminal Pentraxin domain characteristic of the family, and a unique N-terminal domain. It is produced by several cell types including endothelial and mononuclear cells. PTX3 acts as a pattern recognition receptor with non-redundant roles in the innate immune response to several microbial agents including the fungal pathogen Aspergillus fumigatus. Overexpression leads to enhanced pro-inflammatory responses. PTX3 is induced in response to LPS and inflammatory cytokines including TNF-alpha and IL-1 beta.

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⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for Pentraxin 3/TSG-14 (MPTX30)(5)

We have publications tested in 1 confirmed species: Mouse.


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Mouse
(5)
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Showing Publications 1 - 5 of 5.
Publications using MPTX30 Applications Species
D Coltrini, AMK Chandran, M Belleri, PL Poliani, M Cominelli, F Pagani, M Capra, S Calza, S Prioni, L Mauri, A Prinetti, JK Kofler, ML Escolar, M Presta beta-Galactosylceramidase Deficiency Causes Upregulation of Long Pentraxin-3 in the Central Nervous System of Krabbe Patients and Twitcher Mice International Journal of Molecular Sciences, 2022-08-21;23(16):. 2022-08-21 [PMID: 36012705] (Mouse) Mouse
Y Takahashi, R Watanabe, Y Sato, N Ozawa, M Kojima, K Watanabe-K, R Shirai, K Sato, T Hirano, T Watanabe Novel phytopeptide osmotin mimics preventive effects of adiponectin on vascular inflammation and atherosclerosis Metab. Clin. Exp., 2018-02-02;0(0):. 2018-02-02 [PMID: 29410350] (Mouse) Mouse
Yao G, Liang M, Liang N, Yin M, Lu M, Lian J, Wang Y, Sun F MicroRNA-224 is involved in the regulation of mouse cumulus expansion by targeting Ptx3. Mol Cell Endocrinol, 2013-10-18;382(1):244-53. 2013-10-18 [PMID: 24145127] (Mouse) Mouse
Chen , Jianlin, Matzuk , Martin M, Zhou , Xin J, Lu , Christop Endothelial pentraxin 3 contributes to murine ischemic acute kidney injury. Kidney Int, 2012-08-15;82(11):1195-207. 2012-08-15 [PMID: 22895517] (Mouse) Mouse
Han , Bing, Ma , Xuezhong, Zhang , Jianhua, Zhang , Yu, Bai , Xiaohui, Hwang , David M, Keshavjee , Shaf, Levy , Gary A, McGilvray , Ian, Liu , Mingyao Protective effects of long pentraxin PTX3 on lung injury in a severe acute respiratory syndrome model in mice. Lab Invest, 2012-06-25;92(9):1285-96. 2012-06-25 [PMID: 22732935] (Mouse) Mouse

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Bioinformatics

Gene Symbol Ptx3