Mouse Pentraxin 3/TSG-14 DuoSet ELISA, 15 Plate

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Pentraxin 3 (PTX3), also known as TNF-stimulated gene 14 (TSG-14), is a secreted glycoprotein belonging to the Pentraxin family of proteins. It is the prototypical long Pentraxin, exhibiting a C-terminal Pentraxin domain characteristic of the family, and a unique N-terminal domain. It is produced by several cell types including endothelial and mononuclear cells. PTX3 acts as a pattern recognition receptor with non-redundant roles in the innate immune response to several microbial agents including the fungal pathogen Aspergillus fumigatus. Overexpression leads to enhanced pro-inflammatory responses. PTX3 is induced in response to LPS and inflammatory cytokines including TNF-alpha and IL-1 beta.

We have publications tested in 1 confirmed species: Mouse.

Showing Publications 1 - 8 of 8.

Publications using DY2166	Applications	Species
M Oggioni, D Mercurio, D Minuta, S Fumagalli, K Popiolek-B, M Sironi, A Ciechanows, S Ippati, D De Blasio, C Perego, J Mika, C Garlanda, MG De Simoni Long pentraxin PTX3 is upregulated systemically and centrally after experimental neurotrauma, but its depletion leaves unaltered sensorimotor deficits or histopathology Scientific Reports, 2021-05-05;11(1):9616. 2021-05-05 [PMID: 33953334] (Mouse)		Mouse
V Ciancarell, L Lembo-Fazi, I Paciello, AK Bruno, S Jaillon, S Berardi, M Barbagallo, S Meron-Suda, D Cohen, A Molinaro, G Rossi, C Garlanda, ML Bernardini Role of a fluid-phase PRR in fighting an intracellular pathogen: PTX3 in Shigella infection PLoS Pathog., 2018-12-07;14(12):e1007469. 2018-12-07 [PMID: 30532257] (Mouse)		Mouse
D Gr?evi?, M Sironi, S Valentino, L Deban, H Cvija, A Inforzato, N Kova?i?, V Katavi?, T Kelava, I Kalajzi?, A Mantovani, B Bottazzi The Long Pentraxin 3 Plays a Role in Bone Turnover and Repair Front Immunol, 2018-03-05;9(0):417. 2018-03-05 [PMID: 29556234] (Mouse)		Mouse
S Ainsworth, PM Ketter, JJ Yu, RC Grimm, HC May, AP Cap, JP Chambers, MN Guentzel, BP Arulananda Vaccination with a live attenuated Acinetobacter baumannii deficient in thioredoxin provides protection against systemic Acinetobacter infection Vaccine, 2017-05-15;0(0):. 2017-05-15 [PMID: 28522011] (Mouse)		Mouse
Foo , Suan-Sin, Chen , Weiqiang, Taylor , Adam, Sheng , Kuo-Chin, Yu , Xing, Teng , Terk-Shi, Reading , Patrick, Blanchard , Helen, Garlanda , Cecilia, Mantovani , Alberto, Ng , Lisa F P, Herrero , Lara J, Mahalingam , Suresh Role of pentraxin 3 in shaping arthritogenic alphaviral disease: from enhanced viral replication to immunomodulation. PLoS Pathog, 2015-02-19;11(2):e1004649. 2015-02-19 [PMID: 25695775] (Mouse)		Mouse
Ketter P, Guentzel M, Schaffer B, Herzig M, Wu X, Montgomery R, Parida B, Fedyk C, Yu J, Jorgensen J, Chambers J, Cap A, Arulanandam B Severe Acinetobacter baumannii sepsis is associated with elevation of pentraxin 3. Infect Immun, 2014-07-07;82(9):3910-8. 2014-07-07 [PMID: 25001601] (Mouse)		Mouse
D'Angelo C, D'Angelo C, De Luca A, Zelante T, Bonifazi P, Moretti S, Giovannini G, Iannitti RG, Zagarella S, Bozza S, Campo S, Salvatori G, Romani L Exogenous pentraxin 3 restores antifungal resistance and restrains inflammation in murine chronic granulomatous disease. J. Immunol., 2009-09-04;183(7):4609-18. 2009-09-04 [PMID: 19734205] (Mouse)		Mouse
Souza DG, Amaral FA, Fagundes CT, Coelho FM, Arantes RM, Sousa LP, Matzuk MM, Garlanda C, Mantovani A, Dias AA, Teixeira MM The long pentraxin PTX3 is crucial for tissue inflammation after intestinal ischemia and reperfusion in mice. Am. J. Pathol., 2009-03-12;174(4):1309-18. 2009-03-12 [PMID: 19286566] (Mouse)		Mouse

Array DY2166

• Pentraxin 3/TSG-14 Antibodies
• Pentraxin 3/TSG-14 Antibody Pair
• Pentraxin 3/TSG-14 Proteins
• Pentraxin 3/TSG-14 ELISAs
• Pentraxin 3/TSG-14 Proteins and Enzymes