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MOG Antibody (CL2852)

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Western Blot: MOG Antibody (2852) [NBP2-46633] - Lane 1: Marker [kDa] 250, 130, 100, 70, 55, 35, 25, 15, 10. Lane 2: Human Cerebral Cortex tissue
Western Blot: MOG Antibody (2852) [NBP2-46633] - Lane 1: Marker [kDa] 250, 130, 100, 70, 55, 35, 25, 15, 10. Lane 2: Human Cerebral Cortex tissue
Immunohistochemistry-Paraffin: MOG Antibody (2852) [NBP2-46633] - Staining of human liver shows absence of immunoreactivity (negative control).
Immunohistochemistry: MOG Antibody (2852) [NBP2-46633] - Staining of rat cerebellum shows strong immunoreactivity in myelinated neural fibers.
Immunohistochemistry: MOG Antibody (2852) [NBP2-46633] - Staining of mouse cerebellum shows strong immunoreactivity in myelinated neural processes.
Immunohistochemistry-Paraffin: MOG Antibody (2852) [NBP2-46633] - Staining of human cerebral cortex shows strong immunoreactivity in myelinated neural fibers.
Immunohistochemistry: MOG Antibody (2852) [NBP2-46633] - Staining of rat striatum shows strong positivity in myelinated neural processes.
Immunohistochemistry: MOG Antibody (2852) [NBP2-46633] - Staining of mouse corpus callosum shows strong immunoreactivity in myelinated neural fibers.
Immunohistochemistry-Paraffin: MOG Antibody (2852) [NBP2-46633] - Staining of human cerebellum shows strong immunoreactivity in myelinated neural processes.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, IHC
Clone
CL2852
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

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MOG Antibody (CL2852) Summary

Immunogen
Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence ALVGDEVELPCRISPGKNATGMEVGWYRPPFSRVVHLYRNGKDQDGDQAPEYRGRTELLKDAIGEGKVTLRIRNVRFSDEGGFTCFFRDHSYQEEAAMELKVEDPFYWVSPG
Epitope
FSRVVHLYRNGKDQD
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
MOG
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:1000 - 1:2500
  • Immunohistochemistry-Paraffin 1:1000 - 1:2500
  • Western Blot 1 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
MOG Recombinant Protein Antigen (NBP2-46633PEP)

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Protein A purified

Alternate Names for MOG Antibody (CL2852)

  • MGC26137
  • MOG Ig-AluB
  • MOG
  • MOGIG2
  • myelin oligodendrocyte glycoprotein
  • myelin-oligodendrocyte glycoprotein

Background

The product of this gene is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. Due to this localization, it is a primary target antigen involved in immune-mediated demyelination. This protein may be involved in completion and maintenance of the myelin sheath and in cell-cell communication. Alternatively spliced transcript variants encoding different isoforms have been identified.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol MOG
Entrez
Uniprot